Phenotypic variation: exploration and functional genomics
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Oxford
Oxford University Press
2011
|
| Schlagworte: | |
| Online-Zugang: | DE-1046 DE-1047 Volltext |
| Beschreibung: | Includes bibliographical references (pages 200-227) and index Phenotype and functional genomics : introduction -- Evolution -- Genomic architecture and copy number changes -- Linkage, association, and linkage disequilibrium -- Regulation of transcription, splicing, and translation : impact of perturbation on phenotype -- Mitochondria : genome, functions, and phenotype -- Quality surveillance -- Neurodevelopment and functional genomics -- Neurobehavioral disorders -- Molecular analyses of malformation syndromes -- Multiple pathways including environmental factors that lead to a specific phenotype with later onset During the past two decades international collaborative studies have yielded extensive information on genome sequences, genome architecture and their variations. The challenge we now face is to understand how these variations impact structure and function of organelles, physiological systems and phenotype. The goal of this book is to present steps in the pathways of exploration to connect genotype to phenotype and to consider how alterations in genomes impact disease. In this book the author reviews published research in functional genomics carried out primarily since 2006 that sheds light on |
| Beschreibung: | 1 Online-Ressource (xii, 240 pages) |
| ISBN: | 0195379632 0199702047 9780195379631 9780199702046 |
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Datensatz im Suchindex
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| author | Smith, Moyra |
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| id | DE-604.BV043100074 |
| illustrated | Not Illustrated |
| indexdate | 2024-12-06T17:00:48Z |
| institution | BVB |
| isbn | 0195379632 0199702047 9780195379631 9780199702046 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028524265 |
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| owner_facet | DE-1046 DE-1047 |
| physical | 1 Online-Ressource (xii, 240 pages) |
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| publishDate | 2011 |
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| spelling | Smith, Moyra Verfasser aut Phenotypic variation exploration and functional genomics Moyra Smith Oxford Oxford University Press 2011 1 Online-Ressource (xii, 240 pages) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references (pages 200-227) and index Phenotype and functional genomics : introduction -- Evolution -- Genomic architecture and copy number changes -- Linkage, association, and linkage disequilibrium -- Regulation of transcription, splicing, and translation : impact of perturbation on phenotype -- Mitochondria : genome, functions, and phenotype -- Quality surveillance -- Neurodevelopment and functional genomics -- Neurobehavioral disorders -- Molecular analyses of malformation syndromes -- Multiple pathways including environmental factors that lead to a specific phenotype with later onset During the past two decades international collaborative studies have yielded extensive information on genome sequences, genome architecture and their variations. The challenge we now face is to understand how these variations impact structure and function of organelles, physiological systems and phenotype. The goal of this book is to present steps in the pathways of exploration to connect genotype to phenotype and to consider how alterations in genomes impact disease. In this book the author reviews published research in functional genomics carried out primarily since 2006 that sheds light on Genetic Variation Phenotype Congenital Abnormalities / genetics Genomics Nervous System Diseases / genetics Congenital Abnormalities / Genetics Nervous System Diseases / Genetics Science Natural history SCIENCE / Life Sciences / Genetics & Genomics bisacsh Genomics fast Phenotype fast Phenotypic plasticity fast Naturwissenschaft Phenotypic plasticity Genetische Variabilität (DE-588)4264352-1 gnd rswk-swf Phänotyp (DE-588)4248244-6 gnd rswk-swf Genomik (DE-588)4776397-8 gnd rswk-swf Phänotyp (DE-588)4248244-6 s Genomik (DE-588)4776397-8 s 1\p DE-604 Genetische Variabilität (DE-588)4264352-1 s 2\p DE-604 http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=368816 Aggregator Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Smith, Moyra Phenotypic variation exploration and functional genomics Genetic Variation Phenotype Congenital Abnormalities / genetics Genomics Nervous System Diseases / genetics Congenital Abnormalities / Genetics Nervous System Diseases / Genetics Science Natural history SCIENCE / Life Sciences / Genetics & Genomics bisacsh Genomics fast Phenotype fast Phenotypic plasticity fast Naturwissenschaft Phenotypic plasticity Genetische Variabilität (DE-588)4264352-1 gnd Phänotyp (DE-588)4248244-6 gnd Genomik (DE-588)4776397-8 gnd |
| subject_GND | (DE-588)4264352-1 (DE-588)4248244-6 (DE-588)4776397-8 |
| title | Phenotypic variation exploration and functional genomics |
| title_auth | Phenotypic variation exploration and functional genomics |
| title_exact_search | Phenotypic variation exploration and functional genomics |
| title_full | Phenotypic variation exploration and functional genomics Moyra Smith |
| title_fullStr | Phenotypic variation exploration and functional genomics Moyra Smith |
| title_full_unstemmed | Phenotypic variation exploration and functional genomics Moyra Smith |
| title_short | Phenotypic variation |
| title_sort | phenotypic variation exploration and functional genomics |
| title_sub | exploration and functional genomics |
| topic | Genetic Variation Phenotype Congenital Abnormalities / genetics Genomics Nervous System Diseases / genetics Congenital Abnormalities / Genetics Nervous System Diseases / Genetics Science Natural history SCIENCE / Life Sciences / Genetics & Genomics bisacsh Genomics fast Phenotype fast Phenotypic plasticity fast Naturwissenschaft Phenotypic plasticity Genetische Variabilität (DE-588)4264352-1 gnd Phänotyp (DE-588)4248244-6 gnd Genomik (DE-588)4776397-8 gnd |
| topic_facet | Genetic Variation Phenotype Congenital Abnormalities / genetics Genomics Nervous System Diseases / genetics Congenital Abnormalities / Genetics Nervous System Diseases / Genetics Science Natural history SCIENCE / Life Sciences / Genetics & Genomics Phenotypic plasticity Naturwissenschaft Genetische Variabilität Phänotyp Genomik |
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| work_keys_str_mv | AT smithmoyra phenotypicvariationexplorationandfunctionalgenomics |