Applications of toxicogenomics in safety evaluation and risk assessment:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Hoboken, N.J.
John Wiley & Sons
c2011
|
| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | Includes bibliographical references and index Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment--early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation--activities in Japan -- -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach "This book provides a timely overview of toxicogenomics, with special emphasis on the practical applications of this technology to the risk assessment process. Introductory sections are followed by a series of chapters highlighting practical and systematic applications of toxicogenomics in informing the risk assessment process - including the areas of mutagenicity, carcinogenicity, endocrine toxicity, organ-specific toxicity, population monitoring, and ecotoxicology. The book concludes with approaches for the integration of this technology in safety evaluation studies, and an outlook on how toxicogenomics and complementary technologies can reframe the current risk assessment paradigm"--Provided by publisher |
| Beschreibung: | 1 Online-Ressource (xiii, 377 p.) |
| ISBN: | 1118001036 1118001044 1118008987 9781118001035 9781118001042 9781118008980 |
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| 245 | 1 | 0 | |a Applications of toxicogenomics in safety evaluation and risk assessment |c edited by Darrell R. Boverhof, B. Bhaskar Gollapudi |
| 264 | 1 | |a Hoboken, N.J. |b John Wiley & Sons |c c2011 | |
| 300 | |a 1 Online-Ressource (xiii, 377 p.) | ||
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| 500 | |a "This book provides a timely overview of toxicogenomics, with special emphasis on the practical applications of this technology to the risk assessment process. Introductory sections are followed by a series of chapters highlighting practical and systematic applications of toxicogenomics in informing the risk assessment process - including the areas of mutagenicity, carcinogenicity, endocrine toxicity, organ-specific toxicity, population monitoring, and ecotoxicology. The book concludes with approaches for the integration of this technology in safety evaluation studies, and an outlook on how toxicogenomics and complementary technologies can reframe the current risk assessment paradigm"--Provided by publisher | ||
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| 650 | 7 | |a Genetic toxicology |2 fast | |
| 650 | 7 | |a Health risk assessment |2 fast | |
| 650 | 7 | |a Toxicity testing |2 fast | |
| 650 | 4 | |a Toxicogenetics | |
| 650 | 4 | |a Risk Assessment | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Genetic toxicology | |
| 650 | 4 | |a Toxicity testing | |
| 650 | 4 | |a Health risk assessment | |
| 700 | 1 | |a Boverhof, Darrell R. |e Sonstige |4 oth | |
| 700 | 1 | |a Gollapudi, B. Bhaskar |e Sonstige |4 oth | |
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Datensatz im Suchindex
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| id | DE-604.BV043095691 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:17:17Z |
| institution | BVB |
| isbn | 1118001036 1118001044 1118008987 9781118001035 9781118001042 9781118008980 |
| language | English |
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| owner_facet | DE-1046 DE-1047 |
| physical | 1 Online-Ressource (xiii, 377 p.) |
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| publishDate | 2011 |
| publishDateSearch | 2011 |
| publishDateSort | 2011 |
| publisher | John Wiley & Sons |
| record_format | marc |
| spelling | Applications of toxicogenomics in safety evaluation and risk assessment edited by Darrell R. Boverhof, B. Bhaskar Gollapudi Hoboken, N.J. John Wiley & Sons c2011 1 Online-Ressource (xiii, 377 p.) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment--early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation--activities in Japan -- -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach "This book provides a timely overview of toxicogenomics, with special emphasis on the practical applications of this technology to the risk assessment process. Introductory sections are followed by a series of chapters highlighting practical and systematic applications of toxicogenomics in informing the risk assessment process - including the areas of mutagenicity, carcinogenicity, endocrine toxicity, organ-specific toxicity, population monitoring, and ecotoxicology. The book concludes with approaches for the integration of this technology in safety evaluation studies, and an outlook on how toxicogenomics and complementary technologies can reframe the current risk assessment paradigm"--Provided by publisher HEALTH & FITNESS / Diseases / Genetic bisacsh MEDICAL / Genetics bisacsh Genetic toxicology fast Health risk assessment fast Toxicity testing fast Toxicogenetics Risk Assessment Medizin Genetic toxicology Toxicity testing Health risk assessment Boverhof, Darrell R. Sonstige oth Gollapudi, B. Bhaskar Sonstige oth Erscheint auch als Druck-Ausgabe, Hardcover 0-470-44982-9 Erscheint auch als Druck-Ausgabe, Hardcover 978-0-470-44982-0 http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=390128 Aggregator Volltext |
| spellingShingle | Applications of toxicogenomics in safety evaluation and risk assessment HEALTH & FITNESS / Diseases / Genetic bisacsh MEDICAL / Genetics bisacsh Genetic toxicology fast Health risk assessment fast Toxicity testing fast Toxicogenetics Risk Assessment Medizin Genetic toxicology Toxicity testing Health risk assessment |
| title | Applications of toxicogenomics in safety evaluation and risk assessment |
| title_auth | Applications of toxicogenomics in safety evaluation and risk assessment |
| title_exact_search | Applications of toxicogenomics in safety evaluation and risk assessment |
| title_full | Applications of toxicogenomics in safety evaluation and risk assessment edited by Darrell R. Boverhof, B. Bhaskar Gollapudi |
| title_fullStr | Applications of toxicogenomics in safety evaluation and risk assessment edited by Darrell R. Boverhof, B. Bhaskar Gollapudi |
| title_full_unstemmed | Applications of toxicogenomics in safety evaluation and risk assessment edited by Darrell R. Boverhof, B. Bhaskar Gollapudi |
| title_short | Applications of toxicogenomics in safety evaluation and risk assessment |
| title_sort | applications of toxicogenomics in safety evaluation and risk assessment |
| topic | HEALTH & FITNESS / Diseases / Genetic bisacsh MEDICAL / Genetics bisacsh Genetic toxicology fast Health risk assessment fast Toxicity testing fast Toxicogenetics Risk Assessment Medizin Genetic toxicology Toxicity testing Health risk assessment |
| topic_facet | HEALTH & FITNESS / Diseases / Genetic MEDICAL / Genetics Genetic toxicology Health risk assessment Toxicity testing Toxicogenetics Risk Assessment Medizin |
| url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=390128 |
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