The public health emergency medical countermeasures enterprise: innovative strategies to enhance products from discovery through approval : workshop summary
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Washington
National Academies Press
c2010
|
| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | Includes bibliographical references Background. The public health perspective on medical countermeasure development, acquisition, and use -- The FDA perspective on the countermeasures enterprise: moving forward -- Government procurement of science -- Partners in a single mission, diverse concerns and challenges. The growing threat of bioweapons -- Gaps and barriers to international collaboration -- Issues for federal agencies engaged in countermeasures development -- Challenges facing the innovative biopharmaceutical industry -- Research infrastructure and resources -- Liability -- End users: challenges for public health and providers -- Examples of successful countermeasures development and deployment. Features of successful government countermeasures efforts -- countermeasures development in industry -- Partnerships and alternative business models. Venture philanthropy and orphan product development models -- Pharmaceutical shared-risk approaches -- Planning for failure -- Open innovation business strategies -- Public-private partnerships -- Independent third-party facilitation of collaboration -- Strategic investor model -- Engaging industry. Incentives: Push vs. Pull -- Incentives not needed?: making a strong business case -- New paradigms, strategies, a nd tactics for enhancing the countermeasures development enterprise. Outsourcing program management -- Government as a strategic partner --Platform technologies -- Revised PHEMCE implementation plan -- Existing regulatory tools and approaches that can be applied to advance countermeasures development. Opportunities for accelerating approval of medical countermeasures: evolving the regulatory framework -- The way forward: themes from the workshop "During public health emergencies such as pandemic influenza outbreaks or terrorist attacks, effective vaccines, drugs, diagnostics, and other medical countermeasures are essential to protecting national security and the public's well-being. The Public Health Emergency Medical Countermeasures Enterprise (PHEMCE--a partnership among federal, state, and local governments; industry; and academia) is at the forefront of the effort to develop and manufacture these countermeasures. However, despite the PHEMCE's many successes, there are still serious challenges to overcome. Government-funded medical research is not always focused on countermeasures for the most serious potential threats, and it is difficult to engage pharmaceutical and biotechnology companies to develop and manufacture medical countermeasures that have a limited commercial market. At the request of the Secretary of the U.S. Department of Health and Human Services and the Assistant Secretary for Preparedness and Response, the IOM held a workshop February 22-24, 2010, to address challenges facing the PHEMCE. Workshop participants discussed federal policies and procedures affecting the research, development, and approval of medical countermeasures and explored opportunities to improve the process and protect Americans' safety and health." |
| Beschreibung: | 1 Online-Ressource (xiv, 179 p.) |
| ISBN: | 0309150248 0309150256 9780309150248 9780309150255 |
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| 500 | |a "During public health emergencies such as pandemic influenza outbreaks or terrorist attacks, effective vaccines, drugs, diagnostics, and other medical countermeasures are essential to protecting national security and the public's well-being. The Public Health Emergency Medical Countermeasures Enterprise (PHEMCE--a partnership among federal, state, and local governments; industry; and academia) is at the forefront of the effort to develop and manufacture these countermeasures. However, despite the PHEMCE's many successes, there are still serious challenges to overcome. Government-funded medical research is not always focused on countermeasures for the most serious potential threats, and it is difficult to engage pharmaceutical and biotechnology companies to develop and manufacture medical countermeasures that have a limited commercial market. At the request of the Secretary of the U.S. Department of Health and Human Services and the Assistant Secretary for Preparedness and Response, the IOM held a workshop February 22-24, 2010, to address challenges facing the PHEMCE. Workshop participants discussed federal policies and procedures affecting the research, development, and approval of medical countermeasures and explored opportunities to improve the process and protect Americans' safety and health." | ||
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| spelling | The public health emergency medical countermeasures enterprise innovative strategies to enhance products from discovery through approval : workshop summary Theresa Wizemann, Clare Stroud, and Bruce M. Altevogt, rapporteurs ; Forum on Medical and Public Health Preparedness for Catastrophic Events ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies Washington National Academies Press c2010 1 Online-Ressource (xiv, 179 p.) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references Background. The public health perspective on medical countermeasure development, acquisition, and use -- The FDA perspective on the countermeasures enterprise: moving forward -- Government procurement of science -- Partners in a single mission, diverse concerns and challenges. The growing threat of bioweapons -- Gaps and barriers to international collaboration -- Issues for federal agencies engaged in countermeasures development -- Challenges facing the innovative biopharmaceutical industry -- Research infrastructure and resources -- Liability -- End users: challenges for public health and providers -- Examples of successful countermeasures development and deployment. Features of successful government countermeasures efforts -- countermeasures development in industry -- Partnerships and alternative business models. Venture philanthropy and orphan product development models -- Pharmaceutical shared-risk approaches -- Planning for failure -- Open innovation business strategies -- Public-private partnerships -- Independent third-party facilitation of collaboration -- Strategic investor model -- Engaging industry. Incentives: Push vs. Pull -- Incentives not needed?: making a strong business case -- New paradigms, strategies, a nd tactics for enhancing the countermeasures development enterprise. Outsourcing program management -- Government as a strategic partner --Platform technologies -- Revised PHEMCE implementation plan -- Existing regulatory tools and approaches that can be applied to advance countermeasures development. Opportunities for accelerating approval of medical countermeasures: evolving the regulatory framework -- The way forward: themes from the workshop "During public health emergencies such as pandemic influenza outbreaks or terrorist attacks, effective vaccines, drugs, diagnostics, and other medical countermeasures are essential to protecting national security and the public's well-being. The Public Health Emergency Medical Countermeasures Enterprise (PHEMCE--a partnership among federal, state, and local governments; industry; and academia) is at the forefront of the effort to develop and manufacture these countermeasures. However, despite the PHEMCE's many successes, there are still serious challenges to overcome. Government-funded medical research is not always focused on countermeasures for the most serious potential threats, and it is difficult to engage pharmaceutical and biotechnology companies to develop and manufacture medical countermeasures that have a limited commercial market. At the request of the Secretary of the U.S. Department of Health and Human Services and the Assistant Secretary for Preparedness and Response, the IOM held a workshop February 22-24, 2010, to address challenges facing the PHEMCE. Workshop participants discussed federal policies and procedures affecting the research, development, and approval of medical countermeasures and explored opportunities to improve the process and protect Americans' safety and health." POLITICAL SCIENCE / Government / State & Provincial bisacsh Emergency management fast Emergency management / Planning fast Public health fast Congresses Emergency Medical Services / United States Public Health / United States Program Development / United States Emergency management United States Planning Congresses Public health United States Congresses Emergency management Congresses USA (DE-588)1071861417 Konferenzschrift gnd-content Wizemann, Theresa M. Sonstige oth Stroud, Clare Sonstige oth Altevogt, Bruce M. Sonstige oth Institute of Medicine (U.S.) Forum on Medical and Public Health Preparedness for Catastrophic Events Sonstige oth Institute of Medicine (U.S.) Forum on Drug Discovery, Development, and Translation Sonstige oth http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=326069 Aggregator Volltext |
| spellingShingle | The public health emergency medical countermeasures enterprise innovative strategies to enhance products from discovery through approval : workshop summary POLITICAL SCIENCE / Government / State & Provincial bisacsh Emergency management fast Emergency management / Planning fast Public health fast Congresses Emergency Medical Services / United States Public Health / United States Program Development / United States Emergency management United States Planning Congresses Public health United States Congresses Emergency management Congresses |
| subject_GND | (DE-588)1071861417 |
| title | The public health emergency medical countermeasures enterprise innovative strategies to enhance products from discovery through approval : workshop summary |
| title_auth | The public health emergency medical countermeasures enterprise innovative strategies to enhance products from discovery through approval : workshop summary |
| title_exact_search | The public health emergency medical countermeasures enterprise innovative strategies to enhance products from discovery through approval : workshop summary |
| title_full | The public health emergency medical countermeasures enterprise innovative strategies to enhance products from discovery through approval : workshop summary Theresa Wizemann, Clare Stroud, and Bruce M. Altevogt, rapporteurs ; Forum on Medical and Public Health Preparedness for Catastrophic Events ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies |
| title_fullStr | The public health emergency medical countermeasures enterprise innovative strategies to enhance products from discovery through approval : workshop summary Theresa Wizemann, Clare Stroud, and Bruce M. Altevogt, rapporteurs ; Forum on Medical and Public Health Preparedness for Catastrophic Events ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies |
| title_full_unstemmed | The public health emergency medical countermeasures enterprise innovative strategies to enhance products from discovery through approval : workshop summary Theresa Wizemann, Clare Stroud, and Bruce M. Altevogt, rapporteurs ; Forum on Medical and Public Health Preparedness for Catastrophic Events ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies |
| title_short | The public health emergency medical countermeasures enterprise |
| title_sort | the public health emergency medical countermeasures enterprise innovative strategies to enhance products from discovery through approval workshop summary |
| title_sub | innovative strategies to enhance products from discovery through approval : workshop summary |
| topic | POLITICAL SCIENCE / Government / State & Provincial bisacsh Emergency management fast Emergency management / Planning fast Public health fast Congresses Emergency Medical Services / United States Public Health / United States Program Development / United States Emergency management United States Planning Congresses Public health United States Congresses Emergency management Congresses |
| topic_facet | POLITICAL SCIENCE / Government / State & Provincial Emergency management Emergency management / Planning Public health Congresses Emergency Medical Services / United States Public Health / United States Program Development / United States Emergency management United States Planning Congresses Public health United States Congresses Emergency management Congresses USA Konferenzschrift |
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