DNA microarray technology and data analysis in cancer research:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Singapore
World Scientific
©2008
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| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | Includes bibliographical references (pages 105-115) and index ch. 1. DNA microarray technology. 1.1. Experimental procedure. 1.2. Experimental design. 1.3. Quality control. 1.4. Interpretation of DNA microarray data. 1.5. Advantages and disadvantages -- ch. 2. Applications of DNA microarray technology in cancer research. 2.1. Solid tumors. 2.2. Blood cancers. 2.3. Our DNA microarray study using mouse -- ch. 3. Current analytical methods of DNA microarray data. 3.1. Experimental design. 3.2. Method. 3.3. Quality control diagnostics. 3.4. Statistical analysis. 3.5. Coefficient of variation analysis -- ch. 4. A novel method for DNA microarray data analysis : SDL global optimization method. 4.1. Research subjects. 4.2. Experimental design. 4.3. Fold change analysis -- 4.4. More information on SDL global optimization -- ch. 5. Applications of the SDL global optimization method in DNA microarray data analysis. 5.1. Leukemia cell line study. 5.2. Analyses of publicly available human microarray data. 5.3. Overall methodology. 5.4. Experimental results. 5.5. Discussion. 5.6. Conclusion -- ch. 6. General discussion and future directions DNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array data are key to performing the assay and utilizing the data correctly. The most difficult challenge has been the lack of a powerful method to analyze the data for all genes (more than 30,000 genes) simultaneously and to use the microarray data in a decision-making process. In this book, the authors describe DNA microarray technology and data analysis by pointing out current advantages and disadvantages of the technique and available analytical methods. Crucially, new ideas and analytical methods based on the authors' own experience in DNA microarray study and analysis are introduced. It is believed that this new way of interpreting and analyzing microarray data will bring us closer to success in decision-making using the information obtained through the DNA microarray technology |
| Beschreibung: | 1 Online-Ressource (xi, 118 pages) |
| ISBN: | 9789812790453 9789812790460 9812790454 9812790462 |
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| 500 | |a ch. 1. DNA microarray technology. 1.1. Experimental procedure. 1.2. Experimental design. 1.3. Quality control. 1.4. Interpretation of DNA microarray data. 1.5. Advantages and disadvantages -- ch. 2. Applications of DNA microarray technology in cancer research. 2.1. Solid tumors. 2.2. Blood cancers. 2.3. Our DNA microarray study using mouse -- ch. 3. Current analytical methods of DNA microarray data. 3.1. Experimental design. 3.2. Method. 3.3. Quality control diagnostics. 3.4. Statistical analysis. 3.5. Coefficient of variation analysis -- ch. 4. A novel method for DNA microarray data analysis : SDL global optimization method. 4.1. Research subjects. 4.2. Experimental design. 4.3. Fold change analysis -- 4.4. More information on SDL global optimization -- ch. 5. Applications of the SDL global optimization method in DNA microarray data analysis. 5.1. Leukemia cell line study. 5.2. Analyses of publicly available human microarray data. 5.3. Overall methodology. 5.4. Experimental results. 5.5. Discussion. 5.6. Conclusion -- ch. 6. General discussion and future directions | ||
| 500 | |a DNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array data are key to performing the assay and utilizing the data correctly. The most difficult challenge has been the lack of a powerful method to analyze the data for all genes (more than 30,000 genes) simultaneously and to use the microarray data in a decision-making process. In this book, the authors describe DNA microarray technology and data analysis by pointing out current advantages and disadvantages of the technique and available analytical methods. Crucially, new ideas and analytical methods based on the authors' own experience in DNA microarray study and analysis are introduced. It is believed that this new way of interpreting and analyzing microarray data will bring us closer to success in decision-making using the information obtained through the DNA microarray technology | ||
| 650 | 7 | |a MEDICAL / Oncology |2 bisacsh | |
| 650 | 7 | |a HEALTH & FITNESS / Diseases / Cancer |2 bisacsh | |
| 650 | 7 | |a Cancer cells / Growth / Regulation |2 fast | |
| 650 | 7 | |a DNA microarrays |2 fast | |
| 650 | 4 | |a Neoplasms | |
| 650 | 4 | |a Oligonucleotide Array Sequence Analysis / methods | |
| 650 | 4 | |a Data Interpretation, Statistical | |
| 650 | 4 | |a Research | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Cancer cells |x Growth |x Regulation | |
| 650 | 4 | |a DNA microarrays | |
| 700 | 1 | |a Li, Dongguang |e Sonstige |4 oth | |
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Datensatz im Suchindex
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| author | Li, Shaoguang |
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| bvnumber | BV043092632 |
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| dewey-ones | 616 - Diseases |
| dewey-raw | 616.994071 |
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| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| indexdate | 2024-07-10T07:17:11Z |
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| isbn | 9789812790453 9789812790460 9812790454 9812790462 |
| language | English |
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| spelling | Li, Shaoguang Verfasser aut DNA microarray technology and data analysis in cancer research Shaoguang Li, Dongguang Li Singapore World Scientific ©2008 1 Online-Ressource (xi, 118 pages) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references (pages 105-115) and index ch. 1. DNA microarray technology. 1.1. Experimental procedure. 1.2. Experimental design. 1.3. Quality control. 1.4. Interpretation of DNA microarray data. 1.5. Advantages and disadvantages -- ch. 2. Applications of DNA microarray technology in cancer research. 2.1. Solid tumors. 2.2. Blood cancers. 2.3. Our DNA microarray study using mouse -- ch. 3. Current analytical methods of DNA microarray data. 3.1. Experimental design. 3.2. Method. 3.3. Quality control diagnostics. 3.4. Statistical analysis. 3.5. Coefficient of variation analysis -- ch. 4. A novel method for DNA microarray data analysis : SDL global optimization method. 4.1. Research subjects. 4.2. Experimental design. 4.3. Fold change analysis -- 4.4. More information on SDL global optimization -- ch. 5. Applications of the SDL global optimization method in DNA microarray data analysis. 5.1. Leukemia cell line study. 5.2. Analyses of publicly available human microarray data. 5.3. Overall methodology. 5.4. Experimental results. 5.5. Discussion. 5.6. Conclusion -- ch. 6. General discussion and future directions DNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array data are key to performing the assay and utilizing the data correctly. The most difficult challenge has been the lack of a powerful method to analyze the data for all genes (more than 30,000 genes) simultaneously and to use the microarray data in a decision-making process. In this book, the authors describe DNA microarray technology and data analysis by pointing out current advantages and disadvantages of the technique and available analytical methods. Crucially, new ideas and analytical methods based on the authors' own experience in DNA microarray study and analysis are introduced. It is believed that this new way of interpreting and analyzing microarray data will bring us closer to success in decision-making using the information obtained through the DNA microarray technology MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Cancer cells / Growth / Regulation fast DNA microarrays fast Neoplasms Oligonucleotide Array Sequence Analysis / methods Data Interpretation, Statistical Research Medizin Cancer cells Growth Regulation DNA microarrays Li, Dongguang Sonstige oth http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=305162 Aggregator Volltext |
| spellingShingle | Li, Shaoguang DNA microarray technology and data analysis in cancer research MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Cancer cells / Growth / Regulation fast DNA microarrays fast Neoplasms Oligonucleotide Array Sequence Analysis / methods Data Interpretation, Statistical Research Medizin Cancer cells Growth Regulation DNA microarrays |
| title | DNA microarray technology and data analysis in cancer research |
| title_auth | DNA microarray technology and data analysis in cancer research |
| title_exact_search | DNA microarray technology and data analysis in cancer research |
| title_full | DNA microarray technology and data analysis in cancer research Shaoguang Li, Dongguang Li |
| title_fullStr | DNA microarray technology and data analysis in cancer research Shaoguang Li, Dongguang Li |
| title_full_unstemmed | DNA microarray technology and data analysis in cancer research Shaoguang Li, Dongguang Li |
| title_short | DNA microarray technology and data analysis in cancer research |
| title_sort | dna microarray technology and data analysis in cancer research |
| topic | MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Cancer cells / Growth / Regulation fast DNA microarrays fast Neoplasms Oligonucleotide Array Sequence Analysis / methods Data Interpretation, Statistical Research Medizin Cancer cells Growth Regulation DNA microarrays |
| topic_facet | MEDICAL / Oncology HEALTH & FITNESS / Diseases / Cancer Cancer cells / Growth / Regulation DNA microarrays Neoplasms Oligonucleotide Array Sequence Analysis / methods Data Interpretation, Statistical Research Medizin Cancer cells Growth Regulation |
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