Aging of the genome: the dual role of DNA in life and death
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Bibliographic Details
Main Author: Vijg, Jan (Author)
Format: Electronic eBook
Language:English
Published: Oxford Oxford University Press 2007
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Online Access:FAW01
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Item Description:Includes bibliographical references (p. [309]-351) and index
The logic of aging -- Genome structure and function -- Genome maintenance -- Genome instability and accerated aging -- The aging genome -- From genome to phenome -- A genomic limit to life?
Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol
Physical Description:1 Online-Ressource (x, 372 p.)
ISBN:0191524581
9780191524585

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