Aging of the genome: the dual role of DNA in life and death
Gespeichert in:
1. Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Oxford
Oxford University Press
2007
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Schlagworte: | |
Online-Zugang: | FAW01 FAW02 Volltext |
Beschreibung: | Includes bibliographical references (p. [309]-351) and index The logic of aging -- Genome structure and function -- Genome maintenance -- Genome instability and accerated aging -- The aging genome -- From genome to phenome -- A genomic limit to life? Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol |
Beschreibung: | 1 Online-Ressource (x, 372 p.) |
ISBN: | 0191524581 9780191524585 |
Internformat
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500 | |a Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol | ||
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650 | 7 | |a DNA damage |2 fast | |
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Datensatz im Suchindex
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any_adam_object | |
author | Vijg, Jan |
author_facet | Vijg, Jan |
author_role | aut |
author_sort | Vijg, Jan |
author_variant | j v jv |
building | Verbundindex |
bvnumber | BV043074836 |
classification_rvk | WD 5360 WG 3300 WG 3440 WX 7501 |
collection | ZDB-4-EBA |
ctrlnum | (OCoLC)137237241 (DE-599)BVBBV043074836 |
dewey-full | 612.8 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 612 - Human physiology |
dewey-raw | 612.8 |
dewey-search | 612.8 |
dewey-sort | 3612.8 |
dewey-tens | 610 - Medicine and health |
discipline | Biologie Medizin |
format | Electronic eBook |
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id | DE-604.BV043074836 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T07:16:39Z |
institution | BVB |
isbn | 0191524581 9780191524585 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028499028 |
oclc_num | 137237241 |
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owner | DE-1046 DE-1047 |
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physical | 1 Online-Ressource (x, 372 p.) |
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publishDate | 2007 |
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publisher | Oxford University Press |
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spelling | Vijg, Jan Verfasser aut Aging of the genome the dual role of DNA in life and death Jan Vijg Oxford Oxford University Press 2007 1 Online-Ressource (x, 372 p.) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references (p. [309]-351) and index The logic of aging -- Genome structure and function -- Genome maintenance -- Genome instability and accerated aging -- The aging genome -- From genome to phenome -- A genomic limit to life? Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol MEDICAL / Neuroscience bisacsh PSYCHOLOGY / Neuropsychology bisacsh Aging / Genetic aspects fast Apoptosis fast Developmental genetics fast DNA damage fast Genomes fast Aging / genetics DNA / genetics Genome Medizin Aging Genetic aspects Apoptosis Genomes Developmental genetics DNA damage Altern (DE-588)4068596-2 gnd rswk-swf Genom (DE-588)4156640-3 gnd rswk-swf Genom (DE-588)4156640-3 s Altern (DE-588)4068596-2 s 1\p DE-604 Erscheint auch als Druck-Ausgabe, Hardcover 0-19-856922-X Erscheint auch als Druck-Ausgabe, Paperback 0-19-856923-8 Erscheint auch als Druck-Ausgabe, Hardcover 978-0-19-856922-0 Erscheint auch als Druck-Ausgabe, Paperback 978-0-19-856923-7 http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=192122 Aggregator Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Vijg, Jan Aging of the genome the dual role of DNA in life and death MEDICAL / Neuroscience bisacsh PSYCHOLOGY / Neuropsychology bisacsh Aging / Genetic aspects fast Apoptosis fast Developmental genetics fast DNA damage fast Genomes fast Aging / genetics DNA / genetics Genome Medizin Aging Genetic aspects Apoptosis Genomes Developmental genetics DNA damage Altern (DE-588)4068596-2 gnd Genom (DE-588)4156640-3 gnd |
subject_GND | (DE-588)4068596-2 (DE-588)4156640-3 |
title | Aging of the genome the dual role of DNA in life and death |
title_auth | Aging of the genome the dual role of DNA in life and death |
title_exact_search | Aging of the genome the dual role of DNA in life and death |
title_full | Aging of the genome the dual role of DNA in life and death Jan Vijg |
title_fullStr | Aging of the genome the dual role of DNA in life and death Jan Vijg |
title_full_unstemmed | Aging of the genome the dual role of DNA in life and death Jan Vijg |
title_short | Aging of the genome |
title_sort | aging of the genome the dual role of dna in life and death |
title_sub | the dual role of DNA in life and death |
topic | MEDICAL / Neuroscience bisacsh PSYCHOLOGY / Neuropsychology bisacsh Aging / Genetic aspects fast Apoptosis fast Developmental genetics fast DNA damage fast Genomes fast Aging / genetics DNA / genetics Genome Medizin Aging Genetic aspects Apoptosis Genomes Developmental genetics DNA damage Altern (DE-588)4068596-2 gnd Genom (DE-588)4156640-3 gnd |
topic_facet | MEDICAL / Neuroscience PSYCHOLOGY / Neuropsychology Aging / Genetic aspects Apoptosis Developmental genetics DNA damage Genomes Aging / genetics DNA / genetics Genome Medizin Aging Genetic aspects Altern Genom |
url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=192122 |
work_keys_str_mv | AT vijgjan agingofthegenomethedualroleofdnainlifeanddeath |