Oxidative stress and antioxidants: their role in human disease
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York
Nova Biomedical Books
c2009
|
| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | Includes bibliographical references and index Oxidative stress: basic overview / Joaquin Toro and Ramon Rodrigo -- Hypertension / Ramon Rodrigo -- Atherosclerosis / Victor Molina and Ramon Rodrigo -- Postoperative atrial fibrillation / Jose Vinay and Ramon Rodrigo -- Acute renal failure / Joaquin Toro, Victor Molina and Ramon Rodrigo -- Pre-eclampsia / Mauro Parra -- Metabolic syndrome / Rodrigo Castillo -- Diabetes Mellitus / Rodrigo Castillo -- Nonalcoholic steatohepatitis / Juan Gormaz and Ramon Rodrigo -- Neurodegenerative disorders / Rodrigo Pizarro -- Glaucoma / Leonidas Traipe, Rodrigo Castillo and Ramon Rodrigo "Oxidative stress is a relatively new concept that has been widely implicated in biomedical sciences during the last 20 years. It significantly participates in the pathophysiology of highly prevalent diseases such as diabetes, hypertension, preeclampsia, atherosclerosis, acute renal failure, Alzheimer and Parkinson diseases, among others. The metabolism of oxygen by cells generates potentially deleterious reactive oxygen species (ROS). Under normal conditions the rate and magnitude of oxidant formation is balanced by the rate of oxidant elimination However, an imbalance between pro-oxidants and antioxidants results in oxidative stress. Increased ROS levels in the cell have a substantial impact either leading to defective cellular function, aging, or disease. Therefore, a better understanding of the roles of ROS-mediated signaling in normal cellular function as well as in disease is necessary for developing therapeutic tools for oxidative stress-related pathologies. The potential beneficial role of antioxidants is discussed in the light of experimental studies, as well as clinical trials aimed to determine the outcome of patients. 'Oxidative Stress and Antioxidants: Their Role in Human Disease' is a practical guide for pathophysiology of oxidative stress and the latest therapeutic advances to modulate the antioxidant defense. This includes evidence from clinical trials, regarding the use of antioxidants and preconditioning, to protect the organism against ROS."--Publisher's description |
| Beschreibung: | 1 Online-Ressource (xiii, 358 p.) |
| ISBN: | 1608765830 9781608765836 |
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| 245 | 1 | 0 | |a Oxidative stress and antioxidants |b their role in human disease |c Ramon Rodrigo, editor |
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| 500 | |a Includes bibliographical references and index | ||
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| 500 | |a "Oxidative stress is a relatively new concept that has been widely implicated in biomedical sciences during the last 20 years. It significantly participates in the pathophysiology of highly prevalent diseases such as diabetes, hypertension, preeclampsia, atherosclerosis, acute renal failure, Alzheimer and Parkinson diseases, among others. The metabolism of oxygen by cells generates potentially deleterious reactive oxygen species (ROS). Under normal conditions the rate and magnitude of oxidant formation is balanced by the rate of oxidant elimination However, an imbalance between pro-oxidants and antioxidants results in oxidative stress. Increased ROS levels in the cell have a substantial impact either leading to defective cellular function, aging, or disease. Therefore, a better understanding of the roles of ROS-mediated signaling in normal cellular function as well as in disease is necessary for developing therapeutic tools for oxidative stress-related pathologies. The potential beneficial role of antioxidants is discussed in the light of experimental studies, as well as clinical trials aimed to determine the outcome of patients. 'Oxidative Stress and Antioxidants: Their Role in Human Disease' is a practical guide for pathophysiology of oxidative stress and the latest therapeutic advances to modulate the antioxidant defense. This includes evidence from clinical trials, regarding the use of antioxidants and preconditioning, to protect the organism against ROS."--Publisher's description | ||
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| id | DE-604.BV043069510 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:16:30Z |
| institution | BVB |
| isbn | 1608765830 9781608765836 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028493702 |
| oclc_num | 593295535 |
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| owner_facet | DE-1046 DE-1047 |
| physical | 1 Online-Ressource (xiii, 358 p.) |
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| publishDate | 2009 |
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| publishDateSort | 2009 |
| publisher | Nova Biomedical Books |
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| spelling | Oxidative stress and antioxidants their role in human disease Ramon Rodrigo, editor New York Nova Biomedical Books c2009 1 Online-Ressource (xiii, 358 p.) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index Oxidative stress: basic overview / Joaquin Toro and Ramon Rodrigo -- Hypertension / Ramon Rodrigo -- Atherosclerosis / Victor Molina and Ramon Rodrigo -- Postoperative atrial fibrillation / Jose Vinay and Ramon Rodrigo -- Acute renal failure / Joaquin Toro, Victor Molina and Ramon Rodrigo -- Pre-eclampsia / Mauro Parra -- Metabolic syndrome / Rodrigo Castillo -- Diabetes Mellitus / Rodrigo Castillo -- Nonalcoholic steatohepatitis / Juan Gormaz and Ramon Rodrigo -- Neurodegenerative disorders / Rodrigo Pizarro -- Glaucoma / Leonidas Traipe, Rodrigo Castillo and Ramon Rodrigo "Oxidative stress is a relatively new concept that has been widely implicated in biomedical sciences during the last 20 years. It significantly participates in the pathophysiology of highly prevalent diseases such as diabetes, hypertension, preeclampsia, atherosclerosis, acute renal failure, Alzheimer and Parkinson diseases, among others. The metabolism of oxygen by cells generates potentially deleterious reactive oxygen species (ROS). Under normal conditions the rate and magnitude of oxidant formation is balanced by the rate of oxidant elimination However, an imbalance between pro-oxidants and antioxidants results in oxidative stress. Increased ROS levels in the cell have a substantial impact either leading to defective cellular function, aging, or disease. Therefore, a better understanding of the roles of ROS-mediated signaling in normal cellular function as well as in disease is necessary for developing therapeutic tools for oxidative stress-related pathologies. The potential beneficial role of antioxidants is discussed in the light of experimental studies, as well as clinical trials aimed to determine the outcome of patients. 'Oxidative Stress and Antioxidants: Their Role in Human Disease' is a practical guide for pathophysiology of oxidative stress and the latest therapeutic advances to modulate the antioxidant defense. This includes evidence from clinical trials, regarding the use of antioxidants and preconditioning, to protect the organism against ROS."--Publisher's description MEDICAL / Pathology bisacsh MEDICAL / Pathophysiology bisacsh Antioxidants fast Oxidative stress fast Oxidative Stress Antioxidants Disease / etiology Medizin Oxidative stress Rodrigo, Ramon Sonstige oth http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=311097 Aggregator Volltext |
| spellingShingle | Oxidative stress and antioxidants their role in human disease MEDICAL / Pathology bisacsh MEDICAL / Pathophysiology bisacsh Antioxidants fast Oxidative stress fast Oxidative Stress Antioxidants Disease / etiology Medizin Oxidative stress |
| title | Oxidative stress and antioxidants their role in human disease |
| title_auth | Oxidative stress and antioxidants their role in human disease |
| title_exact_search | Oxidative stress and antioxidants their role in human disease |
| title_full | Oxidative stress and antioxidants their role in human disease Ramon Rodrigo, editor |
| title_fullStr | Oxidative stress and antioxidants their role in human disease Ramon Rodrigo, editor |
| title_full_unstemmed | Oxidative stress and antioxidants their role in human disease Ramon Rodrigo, editor |
| title_short | Oxidative stress and antioxidants |
| title_sort | oxidative stress and antioxidants their role in human disease |
| title_sub | their role in human disease |
| topic | MEDICAL / Pathology bisacsh MEDICAL / Pathophysiology bisacsh Antioxidants fast Oxidative stress fast Oxidative Stress Antioxidants Disease / etiology Medizin Oxidative stress |
| topic_facet | MEDICAL / Pathology MEDICAL / Pathophysiology Antioxidants Oxidative stress Oxidative Stress Disease / etiology Medizin |
| url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=311097 |
| work_keys_str_mv | AT rodrigoramon oxidativestressandantioxidantstheirroleinhumandisease |