Heart regeneration: stem cells and beyond
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Singapore
World Scientific Pub. Co.
2012
|
| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | Includes bibliographical references and index I. Introduction to cardiac disease / Erin Bohula and Richard T. Lee -- II. Growth and differentiation of the developing heart / Bram van Wijk [and others] -- III. Does heart regeneration occur? A. Cardiac regeneration in the newt / Thilo Borchardt and Thomas Braun. B. Zebrafish heart regeneration / Robert J. Major and Kenneth D. Poss. C. Regenerative potential of the mammalian heart / May Liang-Lam and William C. Claycomb -- IV. Repopulation of the heart with new cardiomyocytes. A. Induction of cardiomyocyte proliferation / Machteld J. van Amerongen and Felix B. Engel. B. Multipotent progenitor cells in regenerative cardiovascular medicine / Jason T. Lam, Alessandra Moretti and Karl-Ludwig Laugwitz. C. Circulating progenitor cells / Masamichi Koyanagi and Stefanie Dimmeler. D. Pluripotent stem cells for cardiac repair / Kara White Moyes, Scott D. Lundy and Michael A. Laflamme -- V. What is the paracrine effect of stem cells? A. Stem cell therapy for heart repair: the paracrine paradigm / Massimiliano Gnecchi, Maria Mirotsou and Victor J. Dzau. B. Delivery systems to the heart / Kathryn M. Rafferty and Michael E. Davis -- VI. How to create an artificial heart ex vivo? A. The mechanical heart / JoAnn Lindenfeld and Patricia A. Kelly. B. Engineered heart tissue / Thomas Eschenhagen and Wolfram-Hubertus Zimmermann -- VII. The complexity of organ regeneration / Tatyana Novoyatleva and Felix B. Engel -- VIII. Cell therapy trials in patients with coronary heart disease / Kai C. Wollert Injured mammalian hearts do not regenerate but scar. This is a major medical problem, as ischemic heart disease is among the leading causes of morbidity and mortality worldwide. Essential clues for human heart repair are uncovered when zebrafish and newt are found to regenerate cardiac muscle after injury. This book presents the major advances of the last decade in the field of cardiac regeneration. These recent advances include: demonstration that zebrafish, a genetically tractable system, can regenerate heart; the identification of several new stem cell populations in the heart; demonstration that stem cells can be used to improve heart function; and demonstration that induction of cardiomyocyte proliferation is a realistic future option to repair injured hearts. This book also provides detailed reviews of the research on model organisms capable of heart regeneration as well as innovative translational research to achieve regeneration in mammals, that comprises work on blood born stem cells, endogenous cardiac stem cells, paracrine factors, reawakening of cardiomyocyte proliferation, and bioengineering. More importantly, the book, in the concluding chapter, dovetails the studies with a comprehensive overview of clinical trials |
| Beschreibung: | 1 Online-Ressource (xx, 372 pages :) |
| ISBN: | 1280669187 9781280669187 9789814299800 9789814299817 9814299804 9814299812 |
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| 500 | |a Includes bibliographical references and index | ||
| 500 | |a I. Introduction to cardiac disease / Erin Bohula and Richard T. Lee -- II. Growth and differentiation of the developing heart / Bram van Wijk [and others] -- III. Does heart regeneration occur? A. Cardiac regeneration in the newt / Thilo Borchardt and Thomas Braun. B. Zebrafish heart regeneration / Robert J. Major and Kenneth D. Poss. C. Regenerative potential of the mammalian heart / May Liang-Lam and William C. Claycomb -- IV. Repopulation of the heart with new cardiomyocytes. A. Induction of cardiomyocyte proliferation / Machteld J. van Amerongen and Felix B. Engel. B. Multipotent progenitor cells in regenerative cardiovascular medicine / Jason T. Lam, Alessandra Moretti and Karl-Ludwig Laugwitz. C. Circulating progenitor cells / Masamichi Koyanagi and Stefanie Dimmeler. D. Pluripotent stem cells for cardiac repair / Kara White Moyes, Scott D. Lundy and Michael A. Laflamme -- V. What is the paracrine effect of stem cells? A. Stem cell therapy for heart repair: the paracrine paradigm / Massimiliano Gnecchi, Maria Mirotsou and Victor J. Dzau. B. Delivery systems to the heart / Kathryn M. Rafferty and Michael E. Davis -- VI. How to create an artificial heart ex vivo? A. The mechanical heart / JoAnn Lindenfeld and Patricia A. Kelly. B. Engineered heart tissue / Thomas Eschenhagen and Wolfram-Hubertus Zimmermann -- VII. The complexity of organ regeneration / Tatyana Novoyatleva and Felix B. Engel -- VIII. Cell therapy trials in patients with coronary heart disease / Kai C. Wollert | ||
| 500 | |a Injured mammalian hearts do not regenerate but scar. This is a major medical problem, as ischemic heart disease is among the leading causes of morbidity and mortality worldwide. Essential clues for human heart repair are uncovered when zebrafish and newt are found to regenerate cardiac muscle after injury. This book presents the major advances of the last decade in the field of cardiac regeneration. These recent advances include: demonstration that zebrafish, a genetically tractable system, can regenerate heart; the identification of several new stem cell populations in the heart; demonstration that stem cells can be used to improve heart function; and demonstration that induction of cardiomyocyte proliferation is a realistic future option to repair injured hearts. This book also provides detailed reviews of the research on model organisms capable of heart regeneration as well as innovative translational research to achieve regeneration in mammals, that comprises work on blood born stem cells, endogenous cardiac stem cells, paracrine factors, reawakening of cardiomyocyte proliferation, and bioengineering. More importantly, the book, in the concluding chapter, dovetails the studies with a comprehensive overview of clinical trials | ||
| 650 | 7 | |a MEDICAL / Physiology |2 bisacsh | |
| 650 | 7 | |a SCIENCE / Life Sciences / Human Anatomy & Physiology |2 bisacsh | |
| 650 | 7 | |a Heart / Diseases / Treatment |2 fast | |
| 650 | 7 | |a Stem cells / Research |2 fast | |
| 650 | 4 | |a Heart / Diseases / Treatment | |
| 650 | 4 | |a Heart / growth and development | |
| 650 | 4 | |a Heart / Growth | |
| 650 | 4 | |a Heart / physiology | |
| 650 | 4 | |a Regeneration | |
| 650 | 4 | |a Regenerative Medicine / methods | |
| 650 | 4 | |a Physiology | |
| 650 | 4 | |a Science | |
| 650 | 4 | |a Natural history | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Naturwissenschaft | |
| 650 | 4 | |a Stem cells |x Research | |
| 650 | 4 | |a Heart |x Diseases |x Treatment | |
| 700 | 1 | |a Engel, Felix B. |e Sonstige |4 oth | |
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Datensatz im Suchindex
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| building | Verbundindex |
| bvnumber | BV043055534 |
| collection | ZDB-4-EBA |
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| dewey-full | 612.17 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.17 |
| dewey-search | 612.17 |
| dewey-sort | 3612.17 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
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| id | DE-604.BV043055534 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:16:06Z |
| institution | BVB |
| isbn | 1280669187 9781280669187 9789814299800 9789814299817 9814299804 9814299812 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028479726 |
| oclc_num | 797852346 |
| open_access_boolean | |
| owner | DE-1046 DE-1047 |
| owner_facet | DE-1046 DE-1047 |
| physical | 1 Online-Ressource (xx, 372 pages :) |
| psigel | ZDB-4-EBA ZDB-4-EBA FAW_PDA_EBA |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | World Scientific Pub. Co. |
| record_format | marc |
| spelling | Heart regeneration stem cells and beyond edited by Felix B. Engel Singapore World Scientific Pub. Co. 2012 1 Online-Ressource (xx, 372 pages :) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index I. Introduction to cardiac disease / Erin Bohula and Richard T. Lee -- II. Growth and differentiation of the developing heart / Bram van Wijk [and others] -- III. Does heart regeneration occur? A. Cardiac regeneration in the newt / Thilo Borchardt and Thomas Braun. B. Zebrafish heart regeneration / Robert J. Major and Kenneth D. Poss. C. Regenerative potential of the mammalian heart / May Liang-Lam and William C. Claycomb -- IV. Repopulation of the heart with new cardiomyocytes. A. Induction of cardiomyocyte proliferation / Machteld J. van Amerongen and Felix B. Engel. B. Multipotent progenitor cells in regenerative cardiovascular medicine / Jason T. Lam, Alessandra Moretti and Karl-Ludwig Laugwitz. C. Circulating progenitor cells / Masamichi Koyanagi and Stefanie Dimmeler. D. Pluripotent stem cells for cardiac repair / Kara White Moyes, Scott D. Lundy and Michael A. Laflamme -- V. What is the paracrine effect of stem cells? A. Stem cell therapy for heart repair: the paracrine paradigm / Massimiliano Gnecchi, Maria Mirotsou and Victor J. Dzau. B. Delivery systems to the heart / Kathryn M. Rafferty and Michael E. Davis -- VI. How to create an artificial heart ex vivo? A. The mechanical heart / JoAnn Lindenfeld and Patricia A. Kelly. B. Engineered heart tissue / Thomas Eschenhagen and Wolfram-Hubertus Zimmermann -- VII. The complexity of organ regeneration / Tatyana Novoyatleva and Felix B. Engel -- VIII. Cell therapy trials in patients with coronary heart disease / Kai C. Wollert Injured mammalian hearts do not regenerate but scar. This is a major medical problem, as ischemic heart disease is among the leading causes of morbidity and mortality worldwide. Essential clues for human heart repair are uncovered when zebrafish and newt are found to regenerate cardiac muscle after injury. This book presents the major advances of the last decade in the field of cardiac regeneration. These recent advances include: demonstration that zebrafish, a genetically tractable system, can regenerate heart; the identification of several new stem cell populations in the heart; demonstration that stem cells can be used to improve heart function; and demonstration that induction of cardiomyocyte proliferation is a realistic future option to repair injured hearts. This book also provides detailed reviews of the research on model organisms capable of heart regeneration as well as innovative translational research to achieve regeneration in mammals, that comprises work on blood born stem cells, endogenous cardiac stem cells, paracrine factors, reawakening of cardiomyocyte proliferation, and bioengineering. More importantly, the book, in the concluding chapter, dovetails the studies with a comprehensive overview of clinical trials MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Heart / Diseases / Treatment fast Stem cells / Research fast Heart / Diseases / Treatment Heart / growth and development Heart / Growth Heart / physiology Regeneration Regenerative Medicine / methods Physiology Science Natural history Medizin Naturwissenschaft Stem cells Research Heart Diseases Treatment Engel, Felix B. Sonstige oth http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=457227 Aggregator Volltext |
| spellingShingle | Heart regeneration stem cells and beyond MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Heart / Diseases / Treatment fast Stem cells / Research fast Heart / Diseases / Treatment Heart / growth and development Heart / Growth Heart / physiology Regeneration Regenerative Medicine / methods Physiology Science Natural history Medizin Naturwissenschaft Stem cells Research Heart Diseases Treatment |
| title | Heart regeneration stem cells and beyond |
| title_auth | Heart regeneration stem cells and beyond |
| title_exact_search | Heart regeneration stem cells and beyond |
| title_full | Heart regeneration stem cells and beyond edited by Felix B. Engel |
| title_fullStr | Heart regeneration stem cells and beyond edited by Felix B. Engel |
| title_full_unstemmed | Heart regeneration stem cells and beyond edited by Felix B. Engel |
| title_short | Heart regeneration |
| title_sort | heart regeneration stem cells and beyond |
| title_sub | stem cells and beyond |
| topic | MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Heart / Diseases / Treatment fast Stem cells / Research fast Heart / Diseases / Treatment Heart / growth and development Heart / Growth Heart / physiology Regeneration Regenerative Medicine / methods Physiology Science Natural history Medizin Naturwissenschaft Stem cells Research Heart Diseases Treatment |
| topic_facet | MEDICAL / Physiology SCIENCE / Life Sciences / Human Anatomy & Physiology Heart / Diseases / Treatment Stem cells / Research Heart / growth and development Heart / Growth Heart / physiology Regeneration Regenerative Medicine / methods Physiology Science Natural history Medizin Naturwissenschaft Stem cells Research Heart Diseases Treatment |
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| work_keys_str_mv | AT engelfelixb heartregenerationstemcellsandbeyond |