Omic studies of neurodegenerative disease: Part B
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u. a.]
Elsevier
2015
|
| Ausgabe: | 1. ed. |
| Schriftenreihe: | International review of neurobiology
122 |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | IX, 239 S. Ill., graph. Darst. |
| ISBN: | 9780128047620 |
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| 245 | 1 | 0 | |a Omic studies of neurodegenerative disease |n Part B |c ed. by Michael J. Hurley |
| 250 | |a 1. ed. | ||
| 264 | 1 | |a Amsterdam [u. a.] |b Elsevier |c 2015 | |
| 300 | |a IX, 239 S. |b Ill., graph. Darst. | ||
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Datensatz im Suchindex
| _version_ | 1804175413716451328 |
|---|---|
| adam_text | CONTENTS
Contributors vii
Preface ix
1. Utility of Autoantibodies as Biomarkers for Diagnosis and Staging
of Neurodegenerativa Diseases 1
Cassandra DeMarshali, Abhirup Sarkar, Eric P. Nage!ef Eric Goldwaser,
George Godsey, Nimish K. Acharya, and Robert G. Nagele
1. Introduction: A Brief History of Autoantibodies 3
2. A Causal Role for Autoantibodies Revealed in Well-Known Autoimmune
Diseases 4
3. Autoantibodies in Cancer: Byproduct or Biomarker7 8
4. Escalating Involvement of Autoantibodtes m Neurological and Neurocognitivc
Disorders 9
5. Autoantibodies: Abundant, Ubiquitous, and Clinically Useful 19
6. Methods of Autoantibody Detection in Biofluids 24
7. Utility of Autoantibodies as Biomarkers of Disease 29
8. Conclusions and Perspectives 35
Acknowledgments 37
References 37
2. Metabolomics of Neurodegenerative Diseases 53
Alejandro Botas, Hannah Moore Campbell, Xu Han, and
Mirjana Maletic-Savatic
1. Metabolomics in Medicine 55
2. Metabolomics Biomarkers of Disease 56
3. Metabolomics Biomarker Discovery in Neurodegenerative Disorders 61
4. Summary 72
Acknowledgments 73
References 73
3. Parkinson s Disease: In Vivo Brain Metabolomics by MRS 81
Mario Rango
1. Proton MRS 82
2. 1H MRS: Compounds Detectable in Vivo 82
3. Phosphorus MRS 83
v
VI
Contenu
4. Mitochondrial Dysfunction 89
5. Other Findings 89
6. High Magnetic Field 90
7. Parkinson s Disease and Solvent Exposure 90
8. Conclusions 91
References 91
4. Recent Advances and Applications of Metabolomics to Investigate
Neurodegenerative Diseases 95
Clara Ibáñez, Alejandro Cifuentes, and Carolina Simó
1. Introduction 96
2. Metabolomics and Neurodegenerative Disorders 100
3. Conclusions 123
References 126
5. Lipidomics of Human Brain Aging and Alzheimer’s Disease
Pathology 133
Alba Naudi, Rosanna Cabré, Mariona Jové, Victoria Ayala, Hugo Gonzalo,
Manuel Portero-Otin, Isidre Ferrer, and Reinald Pamplona
1. Introduction 134
2. Lipidomics of Human Brain 136
3. Lipidomics of Human Brain Aging 163
4. Lipidomics of Alzheimer s Disease Pathology 168
5. Summary and Future Prospects 177
Acknowledgments 178
References 178
Index
Contents of Recent Volumes
191
195
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| id | DE-604.BV043046493 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T07:15:54Z |
| institution | BVB |
| isbn | 9780128047620 |
| language | English |
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| physical | IX, 239 S. Ill., graph. Darst. |
| publishDate | 2015 |
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| publisher | Elsevier |
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| series | International review of neurobiology |
| series2 | International review of neurobiology |
| spelling | Omic studies of neurodegenerative disease Part B ed. by Michael J. Hurley 1. ed. Amsterdam [u. a.] Elsevier 2015 IX, 239 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier International review of neurobiology 122 International review of neurobiology ... Literaturangaben Hurley, Michael J. Sonstige oth (DE-604)BV042896272 B International review of neurobiology 122 (DE-604)BV002534817 122 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028470994&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Omic studies of neurodegenerative disease International review of neurobiology |
| title | Omic studies of neurodegenerative disease |
| title_auth | Omic studies of neurodegenerative disease |
| title_exact_search | Omic studies of neurodegenerative disease |
| title_full | Omic studies of neurodegenerative disease Part B ed. by Michael J. Hurley |
| title_fullStr | Omic studies of neurodegenerative disease Part B ed. by Michael J. Hurley |
| title_full_unstemmed | Omic studies of neurodegenerative disease Part B ed. by Michael J. Hurley |
| title_short | Omic studies of neurodegenerative disease |
| title_sort | omic studies of neurodegenerative disease |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028470994&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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