The combinatorial index:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
San Diego
Academic Press
c1998
|
| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | With the explosion of combinatorial solid-phase methods, access to information has become one of the main barriers facing a synthetic chemist who is contemplating a combinatorial approach to a medicinal chemistry problem. The Combinatorial Index is an answer to that problem. This compendium of methods from the primary literature provides quick and convenient access to reliable synthetic transformations as well as information on linkers and analytical methods. Each synthetic procedure is preceded by a section entitled"Points of Interest, "which highlights the strengths and weaknesses of the various studies. The index also covers the use of solution-based synthesis for the generation of molecular diversity. Key Features * Organized for rapid retrieval of published information on classes of synthetic transformations, linkers, and analytical methods * Serves as a laboratory manual for bench chemists * Includes a chapter on linkers to assist in choice of linking strategy * Discusses strengths and limitations of the various methods * Contains a structural index showing functional group transformations in solid-phase synthesis Introduction. Background. Linkers for Solid-Phase Synthesis. Combinatorial Solid-Phase Synthesis. Analytical Methods for Solid-Phase Synthesis. The Preparation of Solution Libraries and Combined Approaches at the Solution/Solid-Phase Interface. Appendix 1: Summary of Functional Group Transformations for Combinatorial Solid-Phase Synthesis. Appendix 2: Classification of Heterocyclization Reactions. Appendix 3: Unnatural Biopolymers. Appendix 4: Oligosaccharides. Appendix 5:List of Abbreviations. Index Includes bibliographical references and indexes |
| Beschreibung: | 1 Online-Ressource (xvii, 322 p.) |
| ISBN: | 0080542409 0121413403 1281025860 9780080542409 9780121413408 9781281025869 |
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| 500 | |a With the explosion of combinatorial solid-phase methods, access to information has become one of the main barriers facing a synthetic chemist who is contemplating a combinatorial approach to a medicinal chemistry problem. The Combinatorial Index is an answer to that problem. This compendium of methods from the primary literature provides quick and convenient access to reliable synthetic transformations as well as information on linkers and analytical methods. Each synthetic procedure is preceded by a section entitled"Points of Interest, "which highlights the strengths and weaknesses of the various studies. The index also covers the use of solution-based synthesis for the generation of molecular diversity. Key Features * Organized for rapid retrieval of published information on classes of synthetic transformations, linkers, and analytical methods * Serves as a laboratory manual for bench chemists * Includes a chapter on linkers to assist in choice of linking strategy * Discusses strengths and limitations of the various methods * Contains a structural index showing functional group transformations in solid-phase synthesis | ||
| 500 | |a Introduction. Background. Linkers for Solid-Phase Synthesis. Combinatorial Solid-Phase Synthesis. Analytical Methods for Solid-Phase Synthesis. The Preparation of Solution Libraries and Combined Approaches at the Solution/Solid-Phase Interface. Appendix 1: Summary of Functional Group Transformations for Combinatorial Solid-Phase Synthesis. Appendix 2: Classification of Heterocyclization Reactions. Appendix 3: Unnatural Biopolymers. Appendix 4: Oligosaccharides. Appendix 5:List of Abbreviations. Index | ||
| 500 | |a Includes bibliographical references and indexes | ||
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Datensatz im Suchindex
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| author | Bunin, Barry A. |
| author_facet | Bunin, Barry A. |
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| dewey-ones | 615 - Pharmacology and therapeutics |
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| discipline | Medizin |
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| isbn | 0080542409 0121413403 1281025860 9780080542409 9780121413408 9781281025869 |
| language | English |
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| spelling | Bunin, Barry A. Verfasser aut The combinatorial index Barry A. Bunin San Diego Academic Press c1998 1 Online-Ressource (xvii, 322 p.) txt rdacontent c rdamedia cr rdacarrier With the explosion of combinatorial solid-phase methods, access to information has become one of the main barriers facing a synthetic chemist who is contemplating a combinatorial approach to a medicinal chemistry problem. The Combinatorial Index is an answer to that problem. This compendium of methods from the primary literature provides quick and convenient access to reliable synthetic transformations as well as information on linkers and analytical methods. Each synthetic procedure is preceded by a section entitled"Points of Interest, "which highlights the strengths and weaknesses of the various studies. The index also covers the use of solution-based synthesis for the generation of molecular diversity. Key Features * Organized for rapid retrieval of published information on classes of synthetic transformations, linkers, and analytical methods * Serves as a laboratory manual for bench chemists * Includes a chapter on linkers to assist in choice of linking strategy * Discusses strengths and limitations of the various methods * Contains a structural index showing functional group transformations in solid-phase synthesis Introduction. Background. Linkers for Solid-Phase Synthesis. Combinatorial Solid-Phase Synthesis. Analytical Methods for Solid-Phase Synthesis. The Preparation of Solution Libraries and Combined Approaches at the Solution/Solid-Phase Interface. Appendix 1: Summary of Functional Group Transformations for Combinatorial Solid-Phase Synthesis. Appendix 2: Classification of Heterocyclization Reactions. Appendix 3: Unnatural Biopolymers. Appendix 4: Oligosaccharides. Appendix 5:List of Abbreviations. Index Includes bibliographical references and indexes Combinatorische chemie gtt Peptiden gtt MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Combinatorial chemistry fast Medizin Combinatorial chemistry Handbooks, manuals, etc Molekülbibliothek (DE-588)4420227-1 gnd rswk-swf Molekülbibliothek (DE-588)4420227-1 s 1\p DE-604 http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=199033 Aggregator Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Bunin, Barry A. The combinatorial index Combinatorische chemie gtt Peptiden gtt MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Combinatorial chemistry fast Medizin Combinatorial chemistry Handbooks, manuals, etc Molekülbibliothek (DE-588)4420227-1 gnd |
| subject_GND | (DE-588)4420227-1 |
| title | The combinatorial index |
| title_auth | The combinatorial index |
| title_exact_search | The combinatorial index |
| title_full | The combinatorial index Barry A. Bunin |
| title_fullStr | The combinatorial index Barry A. Bunin |
| title_full_unstemmed | The combinatorial index Barry A. Bunin |
| title_short | The combinatorial index |
| title_sort | the combinatorial index |
| topic | Combinatorische chemie gtt Peptiden gtt MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Combinatorial chemistry fast Medizin Combinatorial chemistry Handbooks, manuals, etc Molekülbibliothek (DE-588)4420227-1 gnd |
| topic_facet | Combinatorische chemie Peptiden MEDICAL / Drug Guides MEDICAL / Pharmacology MEDICAL / Pharmacy MEDICAL / Nursing / Pharmacology Combinatorial chemistry Medizin Combinatorial chemistry Handbooks, manuals, etc Molekülbibliothek |
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