Practical process research & development:
Gespeichert in:
1. Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
San Diego
Academic Press
c2000
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Schlagworte: | |
Online-Zugang: | FAW01 FAW02 Volltext |
Beschreibung: | This book will provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries. Process R & D describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are identified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and academicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R & D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." "Practical Process Research and Development" will be a valuable resource for researchers, managers, and graduate students. * Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" * Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more * Includes over 100 tips for rapid process development * Presents guidelines for implementing and troubleshooting processes Foreword by K. Barry Sharpless. Foreword by Jerome L. Moniot. Preface. About the Author. Approaches to Process Development. Route Selection. Reagent Selection. Solvent Selection. Running the Reaction. Effects of Water. In-Process Controls. Optimizing the Reaction by Minimizing Impurities. Optimizing Catalytic Reactions. Work-Up. Tools for Purifying the Product: Column Chromatography, Crystallization, and Reslurrying. Final Product Form and Impurity Considerations. Vessels and Mixing. Preparing for and Implementing the Scale-up Run. Troubleshooting. Chiral Syntheses. General Index. Reaction Type Index. Reagent Index Includes bibliographical references and indexes |
Beschreibung: | 1 Online-Ressource (xxiii, 354 p.) |
ISBN: | 0080514480 0120594757 1281024058 9780080514482 9780120594757 9781281024053 |
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500 | |a Foreword by K. Barry Sharpless. Foreword by Jerome L. Moniot. Preface. About the Author. Approaches to Process Development. Route Selection. Reagent Selection. Solvent Selection. Running the Reaction. Effects of Water. In-Process Controls. Optimizing the Reaction by Minimizing Impurities. Optimizing Catalytic Reactions. Work-Up. Tools for Purifying the Product: Column Chromatography, Crystallization, and Reslurrying. Final Product Form and Impurity Considerations. Vessels and Mixing. Preparing for and Implementing the Scale-up Run. Troubleshooting. Chiral Syntheses. General Index. Reaction Type Index. Reagent Index | ||
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Datensatz im Suchindex
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any_adam_object | |
author | Anderson, Neal G. |
author_facet | Anderson, Neal G. |
author_role | aut |
author_sort | Anderson, Neal G. |
author_variant | n g a ng nga |
building | Verbundindex |
bvnumber | BV043044563 |
collection | ZDB-4-EBA |
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dewey-ones | 660 - Chemical engineering |
dewey-raw | 660/.28 |
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discipline | Chemie / Pharmazie |
format | Electronic eBook |
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indexdate | 2024-07-10T07:15:51Z |
institution | BVB |
isbn | 0080514480 0120594757 1281024058 9780080514482 9780120594757 9781281024053 |
language | English |
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spelling | Anderson, Neal G. Verfasser aut Practical process research & development Neal G. Anderson Practical process research and development San Diego Academic Press c2000 1 Online-Ressource (xxiii, 354 p.) txt rdacontent c rdamedia cr rdacarrier This book will provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries. Process R & D describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are identified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and academicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R & D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." "Practical Process Research and Development" will be a valuable resource for researchers, managers, and graduate students. * Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" * Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more * Includes over 100 tips for rapid process development * Presents guidelines for implementing and troubleshooting processes Foreword by K. Barry Sharpless. Foreword by Jerome L. Moniot. Preface. About the Author. Approaches to Process Development. Route Selection. Reagent Selection. Solvent Selection. Running the Reaction. Effects of Water. In-Process Controls. Optimizing the Reaction by Minimizing Impurities. Optimizing Catalytic Reactions. Work-Up. Tools for Purifying the Product: Column Chromatography, Crystallization, and Reslurrying. Final Product Form and Impurity Considerations. Vessels and Mixing. Preparing for and Implementing the Scale-up Run. Troubleshooting. Chiral Syntheses. General Index. Reaction Type Index. Reagent Index Includes bibliographical references and indexes Chemical engineering Chemical processes / Design Procesindustrie gtt Chemische industrie gtt Farmaceutische industrie gtt Procestechnologie gtt Research and Development gtt Procesbeheersing gtt Processos químicos larpcal TECHNOLOGY & ENGINEERING / Chemical & Biochemical bisacsh SCIENCE / Chemistry / Industrial & Technical bisacsh Chemical processes fast Chemie Chemical processes Prozessentwicklung Technik (DE-588)4278925-4 gnd rswk-swf Pharmazeutische Chemie (DE-588)4132158-3 gnd rswk-swf Maßstabübertragung (DE-588)4279219-8 gnd rswk-swf Chemischer Prozess (DE-588)4147636-0 gnd rswk-swf Chemischer Prozess (DE-588)4147636-0 s Maßstabübertragung (DE-588)4279219-8 s 1\p DE-604 Prozessentwicklung Technik (DE-588)4278925-4 s Pharmazeutische Chemie (DE-588)4132158-3 s 2\p DE-604 http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=195917 Aggregator Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Anderson, Neal G. Practical process research & development Chemical engineering Chemical processes / Design Procesindustrie gtt Chemische industrie gtt Farmaceutische industrie gtt Procestechnologie gtt Research and Development gtt Procesbeheersing gtt Processos químicos larpcal TECHNOLOGY & ENGINEERING / Chemical & Biochemical bisacsh SCIENCE / Chemistry / Industrial & Technical bisacsh Chemical processes fast Chemie Chemical processes Prozessentwicklung Technik (DE-588)4278925-4 gnd Pharmazeutische Chemie (DE-588)4132158-3 gnd Maßstabübertragung (DE-588)4279219-8 gnd Chemischer Prozess (DE-588)4147636-0 gnd |
subject_GND | (DE-588)4278925-4 (DE-588)4132158-3 (DE-588)4279219-8 (DE-588)4147636-0 |
title | Practical process research & development |
title_alt | Practical process research and development |
title_auth | Practical process research & development |
title_exact_search | Practical process research & development |
title_full | Practical process research & development Neal G. Anderson |
title_fullStr | Practical process research & development Neal G. Anderson |
title_full_unstemmed | Practical process research & development Neal G. Anderson |
title_short | Practical process research & development |
title_sort | practical process research development |
topic | Chemical engineering Chemical processes / Design Procesindustrie gtt Chemische industrie gtt Farmaceutische industrie gtt Procestechnologie gtt Research and Development gtt Procesbeheersing gtt Processos químicos larpcal TECHNOLOGY & ENGINEERING / Chemical & Biochemical bisacsh SCIENCE / Chemistry / Industrial & Technical bisacsh Chemical processes fast Chemie Chemical processes Prozessentwicklung Technik (DE-588)4278925-4 gnd Pharmazeutische Chemie (DE-588)4132158-3 gnd Maßstabübertragung (DE-588)4279219-8 gnd Chemischer Prozess (DE-588)4147636-0 gnd |
topic_facet | Chemical engineering Chemical processes / Design Procesindustrie Chemische industrie Farmaceutische industrie Procestechnologie Research and Development Procesbeheersing Processos químicos TECHNOLOGY & ENGINEERING / Chemical & Biochemical SCIENCE / Chemistry / Industrial & Technical Chemical processes Chemie Prozessentwicklung Technik Pharmazeutische Chemie Maßstabübertragung Chemischer Prozess |
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