The molecular biology of cancer: a bridge from bench to bedside
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York
Wiley-Blackwell
2013
|
| Ausgabe: | Second edition |
| Schlagworte: | |
| Online-Zugang: | TUM01 Volltext |
| Beschreibung: | 1 Online-Ressource (xii, 620 Seiten) |
| ISBN: | 9781118430842 1118430840 |
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| 100 | 1 | |a Pelengaris, Stella |4 edt | |
| 245 | 1 | 0 | |a The molecular biology of cancer |b a bridge from bench to bedside |c edited by Stella Pelengaris and Michael Khan |
| 250 | |a Second edition | ||
| 264 | 1 | |a New York |b Wiley-Blackwell |c 2013 | |
| 300 | |a 1 Online-Ressource (xii, 620 Seiten) | ||
| 336 | |b txt |2 rdacontent | ||
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| 505 | 8 | |a This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. The text offers in-depth coverage of traditional areas of study, while also discussing areas of controversy and emerging importance and highlighting future directions for research | |
| 505 | 8 | |a Cover; Title page; Copyright page; Contents; Contributors; Preface to the Second Edition; Acknowledgments; Dedication; About the Companion Website; Introduction; 1: Overview of Cancer Biology; Introduction; Cancer incidence and epidemiology; Towards a definition of cancer; Classification of cancer; It is surprisingly difficult to define cancer in practice; Cancers may not always be clinically apparent; If we find a cancer what do we do with it?; Causes of cancer; The clonal evolution theory; Becoming a cancer cell -- multistage carcinogenesis; The cell of origin in cancer | |
| 505 | 8 | |a The cancer stem cell and nicheA chemotherapy-resistant niche; Targeting the cancer-initiating cells; The latent niche; Cancer is a genetic disease; Cancers (and Darwin's finches) evolve by mutation and natural selection; Blame the parents -- inherited single gene defects and susceptibility to cancer; Loss of heterozygosity and comparative genome hybridization; Haploinsufficiency; Blame everyone -- complex polygenic mechanisms and inherited susceptibility to cancer; An apology to Jean-Baptiste Lamarck: cancer is an epigenetic disease (but you were wrong about giraffes) | |
| 505 | 8 | |a "So it isn't really junk after all." Noncoding DNAThe cancer "roadmap" -- What kinds of genes are epimutated in cancer?; Viruses and the beginnings of cancer biology; Hens and teeth or bears and woods? The hens have it -- cancer is rare; The barriers to cancer; The tumor suppressors; Avoiding suicidal urges; Other forms of death; Avoiding senescence; Oncogene-induced senescence; Oncogenes as tumor suppressors; What is the secret of cancer developme ... "timing"; Location, location, location -- the cancer environment: nanny or spartan state; Cancer cells as "cuckoos." | |
| 505 | 8 | |a Cancers, chronic inflammation, and tissue remodelingLiaisons dangereuses encourage tumorigenesis; Policemen or agent provocateur -- immunocytes in cancer; Cancer goes agricultural; The field effect; The seed and the soil: metastatic spread; Cancer superhighways -- blood vessels and lymphatics; On your bike and turn the lights off before you go; Catching cancer; Hammering the hallmarks; Cancer -- Achilles' heel and Paris' arrow; Getting the GIST of oncogene addiction; Cooking with ERBBs; Painting a portrait of cancer; Savile Row tailoring of cancer therapies; The pitfalls of tumor profiling | |
| 505 | 8 | |a A cancer protein expression profileThe drugs don't work; The addictive personality of cancer -- synthetic lethality and non-oncogene addiction; Mechanism of origin rather than cell of origin -- towards a new functional taxonomy of cancer; Is it worth it?; Conclusions and future directions; Bibliography; Appendix 1.1 History of cancer; 2: The Burden of Cancer; Introduction; Lung cancer; Incidence; Pathology; Clinical features; Diagnostic and staging investigations; Treatment; Breast cancer; Pathology; Clinical features; Diagnostic procedures and investigations; Treatment; Chemotherapy | |
| 650 | 4 | |a Cancer / Genetic aspects | |
| 650 | 4 | |a Cancer / Molecular aspects | |
| 650 | 4 | |a Molecular biology | |
| 650 | 4 | |a Neoplasms / Genetics | |
| 650 | 7 | |a HEALTH & FITNESS / Diseases / Cancer |2 bisacsh | |
| 650 | 7 | |a MEDICAL / Oncology |2 bisacsh | |
| 650 | 7 | |a Cancer cells |2 fast | |
| 650 | 7 | |a Cancer / Genetic aspects |2 fast | |
| 650 | 7 | |a Cancer / Molecular aspects |2 fast | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Cancer |x Molecular aspects | |
| 650 | 4 | |a Cancer |x Genetic aspects | |
| 650 | 4 | |a Cancer cells | |
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Datensatz im Suchindex
| _version_ | 1804175029047394304 |
|---|---|
| any_adam_object | |
| author2 | Pelengaris, Stella Khan, Michael |
| author2_role | edt edt |
| author2_variant | s p sp m k mk |
| author_facet | Pelengaris, Stella Khan, Michael |
| building | Verbundindex |
| bvnumber | BV042795897 |
| classification_rvk | XH 1700 XH 2550 XH 2567 |
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| contents | This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. The text offers in-depth coverage of traditional areas of study, while also discussing areas of controversy and emerging importance and highlighting future directions for research Cover; Title page; Copyright page; Contents; Contributors; Preface to the Second Edition; Acknowledgments; Dedication; About the Companion Website; Introduction; 1: Overview of Cancer Biology; Introduction; Cancer incidence and epidemiology; Towards a definition of cancer; Classification of cancer; It is surprisingly difficult to define cancer in practice; Cancers may not always be clinically apparent; If we find a cancer what do we do with it?; Causes of cancer; The clonal evolution theory; Becoming a cancer cell -- multistage carcinogenesis; The cell of origin in cancer The cancer stem cell and nicheA chemotherapy-resistant niche; Targeting the cancer-initiating cells; The latent niche; Cancer is a genetic disease; Cancers (and Darwin's finches) evolve by mutation and natural selection; Blame the parents -- inherited single gene defects and susceptibility to cancer; Loss of heterozygosity and comparative genome hybridization; Haploinsufficiency; Blame everyone -- complex polygenic mechanisms and inherited susceptibility to cancer; An apology to Jean-Baptiste Lamarck: cancer is an epigenetic disease (but you were wrong about giraffes) "So it isn't really junk after all." Noncoding DNAThe cancer "roadmap" -- What kinds of genes are epimutated in cancer?; Viruses and the beginnings of cancer biology; Hens and teeth or bears and woods? The hens have it -- cancer is rare; The barriers to cancer; The tumor suppressors; Avoiding suicidal urges; Other forms of death; Avoiding senescence; Oncogene-induced senescence; Oncogenes as tumor suppressors; What is the secret of cancer developme ... "timing"; Location, location, location -- the cancer environment: nanny or spartan state; Cancer cells as "cuckoos." Cancers, chronic inflammation, and tissue remodelingLiaisons dangereuses encourage tumorigenesis; Policemen or agent provocateur -- immunocytes in cancer; Cancer goes agricultural; The field effect; The seed and the soil: metastatic spread; Cancer superhighways -- blood vessels and lymphatics; On your bike and turn the lights off before you go; Catching cancer; Hammering the hallmarks; Cancer -- Achilles' heel and Paris' arrow; Getting the GIST of oncogene addiction; Cooking with ERBBs; Painting a portrait of cancer; Savile Row tailoring of cancer therapies; The pitfalls of tumor profiling A cancer protein expression profileThe drugs don't work; The addictive personality of cancer -- synthetic lethality and non-oncogene addiction; Mechanism of origin rather than cell of origin -- towards a new functional taxonomy of cancer; Is it worth it?; Conclusions and future directions; Bibliography; Appendix 1.1 History of cancer; 2: The Burden of Cancer; Introduction; Lung cancer; Incidence; Pathology; Clinical features; Diagnostic and staging investigations; Treatment; Breast cancer; Pathology; Clinical features; Diagnostic procedures and investigations; Treatment; Chemotherapy |
| ctrlnum | (ZDB-4-NLEBK)561435 (OCoLC)831118459 (DE-599)BVBBV042795897 |
| dewey-full | 616.99/4042 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.99/4042 |
| dewey-search | 616.99/4042 |
| dewey-sort | 3616.99 44042 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | Second edition |
| format | Electronic eBook |
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| indexdate | 2024-07-10T07:09:47Z |
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| isbn | 9781118430842 1118430840 |
| language | English |
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| publisher | Wiley-Blackwell |
| record_format | marc |
| spelling | Pelengaris, Stella edt The molecular biology of cancer a bridge from bench to bedside edited by Stella Pelengaris and Michael Khan Second edition New York Wiley-Blackwell 2013 1 Online-Ressource (xii, 620 Seiten) txt rdacontent c rdamedia cr rdacarrier This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. The text offers in-depth coverage of traditional areas of study, while also discussing areas of controversy and emerging importance and highlighting future directions for research Cover; Title page; Copyright page; Contents; Contributors; Preface to the Second Edition; Acknowledgments; Dedication; About the Companion Website; Introduction; 1: Overview of Cancer Biology; Introduction; Cancer incidence and epidemiology; Towards a definition of cancer; Classification of cancer; It is surprisingly difficult to define cancer in practice; Cancers may not always be clinically apparent; If we find a cancer what do we do with it?; Causes of cancer; The clonal evolution theory; Becoming a cancer cell -- multistage carcinogenesis; The cell of origin in cancer The cancer stem cell and nicheA chemotherapy-resistant niche; Targeting the cancer-initiating cells; The latent niche; Cancer is a genetic disease; Cancers (and Darwin's finches) evolve by mutation and natural selection; Blame the parents -- inherited single gene defects and susceptibility to cancer; Loss of heterozygosity and comparative genome hybridization; Haploinsufficiency; Blame everyone -- complex polygenic mechanisms and inherited susceptibility to cancer; An apology to Jean-Baptiste Lamarck: cancer is an epigenetic disease (but you were wrong about giraffes) "So it isn't really junk after all." Noncoding DNAThe cancer "roadmap" -- What kinds of genes are epimutated in cancer?; Viruses and the beginnings of cancer biology; Hens and teeth or bears and woods? The hens have it -- cancer is rare; The barriers to cancer; The tumor suppressors; Avoiding suicidal urges; Other forms of death; Avoiding senescence; Oncogene-induced senescence; Oncogenes as tumor suppressors; What is the secret of cancer developme ... "timing"; Location, location, location -- the cancer environment: nanny or spartan state; Cancer cells as "cuckoos." Cancers, chronic inflammation, and tissue remodelingLiaisons dangereuses encourage tumorigenesis; Policemen or agent provocateur -- immunocytes in cancer; Cancer goes agricultural; The field effect; The seed and the soil: metastatic spread; Cancer superhighways -- blood vessels and lymphatics; On your bike and turn the lights off before you go; Catching cancer; Hammering the hallmarks; Cancer -- Achilles' heel and Paris' arrow; Getting the GIST of oncogene addiction; Cooking with ERBBs; Painting a portrait of cancer; Savile Row tailoring of cancer therapies; The pitfalls of tumor profiling A cancer protein expression profileThe drugs don't work; The addictive personality of cancer -- synthetic lethality and non-oncogene addiction; Mechanism of origin rather than cell of origin -- towards a new functional taxonomy of cancer; Is it worth it?; Conclusions and future directions; Bibliography; Appendix 1.1 History of cancer; 2: The Burden of Cancer; Introduction; Lung cancer; Incidence; Pathology; Clinical features; Diagnostic and staging investigations; Treatment; Breast cancer; Pathology; Clinical features; Diagnostic procedures and investigations; Treatment; Chemotherapy Cancer / Genetic aspects Cancer / Molecular aspects Molecular biology Neoplasms / Genetics HEALTH & FITNESS / Diseases / Cancer bisacsh MEDICAL / Oncology bisacsh Cancer cells fast Cancer / Genetic aspects fast Cancer / Molecular aspects fast Medizin Cancer Molecular aspects Cancer Genetic aspects Cancer cells Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Krebs Medizin (DE-588)4073781-0 s Molekularbiologie (DE-588)4039983-7 s 2\p DE-604 Khan, Michael edt Erscheint auch als Druck-Ausgabe, Hardcover 978-1-118-02287-0 http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=561435 Aggregator Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | The molecular biology of cancer a bridge from bench to bedside This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. The text offers in-depth coverage of traditional areas of study, while also discussing areas of controversy and emerging importance and highlighting future directions for research Cover; Title page; Copyright page; Contents; Contributors; Preface to the Second Edition; Acknowledgments; Dedication; About the Companion Website; Introduction; 1: Overview of Cancer Biology; Introduction; Cancer incidence and epidemiology; Towards a definition of cancer; Classification of cancer; It is surprisingly difficult to define cancer in practice; Cancers may not always be clinically apparent; If we find a cancer what do we do with it?; Causes of cancer; The clonal evolution theory; Becoming a cancer cell -- multistage carcinogenesis; The cell of origin in cancer The cancer stem cell and nicheA chemotherapy-resistant niche; Targeting the cancer-initiating cells; The latent niche; Cancer is a genetic disease; Cancers (and Darwin's finches) evolve by mutation and natural selection; Blame the parents -- inherited single gene defects and susceptibility to cancer; Loss of heterozygosity and comparative genome hybridization; Haploinsufficiency; Blame everyone -- complex polygenic mechanisms and inherited susceptibility to cancer; An apology to Jean-Baptiste Lamarck: cancer is an epigenetic disease (but you were wrong about giraffes) "So it isn't really junk after all." Noncoding DNAThe cancer "roadmap" -- What kinds of genes are epimutated in cancer?; Viruses and the beginnings of cancer biology; Hens and teeth or bears and woods? The hens have it -- cancer is rare; The barriers to cancer; The tumor suppressors; Avoiding suicidal urges; Other forms of death; Avoiding senescence; Oncogene-induced senescence; Oncogenes as tumor suppressors; What is the secret of cancer developme ... "timing"; Location, location, location -- the cancer environment: nanny or spartan state; Cancer cells as "cuckoos." Cancers, chronic inflammation, and tissue remodelingLiaisons dangereuses encourage tumorigenesis; Policemen or agent provocateur -- immunocytes in cancer; Cancer goes agricultural; The field effect; The seed and the soil: metastatic spread; Cancer superhighways -- blood vessels and lymphatics; On your bike and turn the lights off before you go; Catching cancer; Hammering the hallmarks; Cancer -- Achilles' heel and Paris' arrow; Getting the GIST of oncogene addiction; Cooking with ERBBs; Painting a portrait of cancer; Savile Row tailoring of cancer therapies; The pitfalls of tumor profiling A cancer protein expression profileThe drugs don't work; The addictive personality of cancer -- synthetic lethality and non-oncogene addiction; Mechanism of origin rather than cell of origin -- towards a new functional taxonomy of cancer; Is it worth it?; Conclusions and future directions; Bibliography; Appendix 1.1 History of cancer; 2: The Burden of Cancer; Introduction; Lung cancer; Incidence; Pathology; Clinical features; Diagnostic and staging investigations; Treatment; Breast cancer; Pathology; Clinical features; Diagnostic procedures and investigations; Treatment; Chemotherapy Cancer / Genetic aspects Cancer / Molecular aspects Molecular biology Neoplasms / Genetics HEALTH & FITNESS / Diseases / Cancer bisacsh MEDICAL / Oncology bisacsh Cancer cells fast Cancer / Genetic aspects fast Cancer / Molecular aspects fast Medizin Cancer Molecular aspects Cancer Genetic aspects Cancer cells Krebs Medizin (DE-588)4073781-0 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| subject_GND | (DE-588)4073781-0 (DE-588)4039983-7 (DE-588)4143413-4 |
| title | The molecular biology of cancer a bridge from bench to bedside |
| title_auth | The molecular biology of cancer a bridge from bench to bedside |
| title_exact_search | The molecular biology of cancer a bridge from bench to bedside |
| title_full | The molecular biology of cancer a bridge from bench to bedside edited by Stella Pelengaris and Michael Khan |
| title_fullStr | The molecular biology of cancer a bridge from bench to bedside edited by Stella Pelengaris and Michael Khan |
| title_full_unstemmed | The molecular biology of cancer a bridge from bench to bedside edited by Stella Pelengaris and Michael Khan |
| title_short | The molecular biology of cancer |
| title_sort | the molecular biology of cancer a bridge from bench to bedside |
| title_sub | a bridge from bench to bedside |
| topic | Cancer / Genetic aspects Cancer / Molecular aspects Molecular biology Neoplasms / Genetics HEALTH & FITNESS / Diseases / Cancer bisacsh MEDICAL / Oncology bisacsh Cancer cells fast Cancer / Genetic aspects fast Cancer / Molecular aspects fast Medizin Cancer Molecular aspects Cancer Genetic aspects Cancer cells Krebs Medizin (DE-588)4073781-0 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| topic_facet | Cancer / Genetic aspects Cancer / Molecular aspects Molecular biology Neoplasms / Genetics HEALTH & FITNESS / Diseases / Cancer MEDICAL / Oncology Cancer cells Medizin Cancer Molecular aspects Cancer Genetic aspects Krebs Medizin Molekularbiologie Aufsatzsammlung |
| url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=561435 |
| work_keys_str_mv | AT pelengarisstella themolecularbiologyofcancerabridgefrombenchtobedside AT khanmichael themolecularbiologyofcancerabridgefrombenchtobedside |