The Regulation of DNA Replication and Transcription:
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Bibliographische Detailangaben
1. Verfasser: Beljanski, Mirko (VerfasserIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: New York Demos Medical Publishing 2013
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Online-Zugang:Volltext
Beschreibung:Description based upon print version of record
The ""Regulation of DNA Replication and Transcription"" explores basic processes of DNA replication and transcription in an effort to identify the mechanisms responsible for the release of genetic information and its role in the regulation of cellular events. Concerned with discovering the fundamental concept that might integrate and explain the wide range of existing lines of evidence, the author reports and interprets the results of experiments conducted in an impressive range of biological systems. Focused on complex mechanisms at the biochemical level, these studies allow analysis of the p
Cover; Title; Copyright; Contents; Foreword; Preface; Introduction; 1. Initiation and Control of DNA Replication; Introduction; Biosynthesis of DNA; Different DNA Polymerases; Opening of the Double Helix and Replication of the DNA Strands; Initiation of DNA Synthesis; RNA Primers; RNA Primers and Replication of Phage Circular DNA; RNA Primers and Discontinuous DNA Synthesis in vivo; Exogenously Prepared RNA Primers and DNA Replication; Specificity of RNA Primers; Multiple Initiation Sites; RNA Primers and the Genesis of Leukocytes and Platelets in situ
Ribosomal RHAs as Source of RNA PrimersInhibitors of DNA Synthesis; Effect of Polyribonucleotides; Effect of Antimitotic Compounds on DNA Replication; Summary; 2. RNA Polymerases and Release of Information from DNA; Introduction; 'Mosaic' Messenger RNAs in Eukaryotes; Variety of RNA Polymerases; Various Factors in the Activity of RNA Polymerases; DNA Templates Used by RNA Polymerases; Initiation of Transcription; Accuracy of DNA Transcription; Initiation of Transcription and Rifampicin; RNA Chain Elongation; RNA Chain Termination; Transcription of DNA in Chromatin
Small Nuclear RNA and Transcription of DNAPeptides and DNA Transcription; Plant Hormones and DNA Transcription; Inhibition of Transcription by DNA-Binding Molecules; Summary; 3. Hormones in the Release of Specific Information from DNA; Introduction; Chromatin Structure in Eukaryotes; Steroid Receptors and Destabilization of Chromatin DNA; Interaction of Steroid Hormones with DNA; Effect of Estrogens in DNA Replication; Phytohormones and DNA Synthesis; Actinomycin D and Steroid-Receptor Complex Fixation to Chromatin; Estradiol and Increase of RNA Polymerase Synthesis
Steroid Hormones and Release of Information in Castrated AnimalsControl of RNA and Protein Synthesis by Hormones; Hormones and the Release of Information in Cancer Cells; RNA Induction by Steroid Hormones in Non-Target Tissues; Hormonal RNA in the Release of Information; Competition between Hormones and RNA Primers; Summary; 4. Exogenous RNAs in Gene Expression and Transformation of Cells; Introduction; Preexisting mRNA and Translation in situ; Cell Differentiation and DNA Replication; Small RNA in Translation; Relationship with Release of Information
Giant Nuclear RNA as Source of RNA FragmentsRNA and in vitro Differentiation of Some Tissues; Exogenous RNA, Inducer of Neural Cells; RNA Inducer of Heart Tissue in Chick Embryo; RNA as Epigenetic Signal during Development; Transformation of Cells by RNA; RNA Fragments as Promoters of Leukocyte Genesis in Mammals Depleted by Anticancer Drugs; Transformation of Oncogenic Agrobacterium tumefaciens into Non-Oncogenic Bacteria by an RNA from Escherichia coli; Information Transfer from RNA to DNA by RNA-Dependent DNA Polymerase; Induction of Plant Tumors by Small RNA
Includes bibliographical references and index
Beschreibung:1 Online-Ressource (221 p.)
ISBN:9781617051821
1617051829
1620700190
9781620700198
9781306135535
1306135532

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