Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP):
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Dordrecht
Springer
[2015]
|
| Schriftenreihe: | Subcellular biochemistry
76 |
| Schlagworte: | |
| Online-Zugang: | TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource (xxii, 395 Seiten) Illustrationen |
| ISBN: | 9789401771979 |
| DOI: | 10.1007/978-94-017-7197-9 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804174942196989952 |
|---|---|
| adam_text | NEURONAL TISSUE-NONSPECIFIC ALKALINE PHOSPHATASE (TNAP)
/
: 2015
TABLE OF CONTENTS / INHALTSVERZEICHNIS
1 CLINICAL FORMS AND ANIMAL MODELS OF HYPOPHOSPHATASIA
2 MOLECULAR GENETICS OF HYPOPHOSPHATASIA AND PHENOTYPE-GENOTYPE
CORRELATIONS
3 GENETICALLY MODIFIED MICE FOR STUDYING TNAP FUNCTION
4 TISSUE-NONSPECIFIC ALKALINE PHOSPHATASE IN THE DEVELOPING BRAIN AND IN
ADULT NEUROGENESIS
5 REDISCOVERING TNAP IN THE BRAIN: A MAJOR ROLE IN REGULATING THE
FUNCTION AND DEVELOPMENT OF THE CEREBRAL CORTEX
6 TNAP IN THE RETINA
7 TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE (TNAP) IN VESSELS OF THE
BRAIN
8 WHAT CAN WE LEARN ABOUT THE NEURAL FUNCTIONS OF TNAP FROM STUDIES ON
OTHER ORGANS AND TISSUES?
9 TNAP, AN ESSENTIAL PLAYER IN MEMBRANE LIPID RAFTS OF NEURONAL CELLS
10 SIGNAL TRANSDUCTION PATHWAYS OF TNAP: MOLECULAR NETWORK ANALYSES
11 VITAMIN B-6 METABOLISM AND INTERACTIONS WITH TNAP
12 TETRAMISOLE AND LEVAMISOLE SUPPRESS NEURONAL ACTIVITY INDEPENDENTLY
FROM THEIR INHIBITORY ACTION ON TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE
IN MOUSE CORTEX
13 TNAP AND PAIN CONTROL
14 NEUROLOGICAL SYMPTOMS OF HYPOPHOSPHATASIA
15 RECOMBINANT ENZYME REPLACEMENT THERAPY IN HYPOPHOSPHATASIA
16 NEUROGENETIC ASPECTS OF HYPERPHOSPHATASIA IN MABRY SYNDROME
17 THE ROLE OF TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE (TNAP) IN
NEURODEGENERATIVE DISEASES: ALZHEIMER’S DISEASE IN THE FOCUS
18 TNAP PLAYS A KEY ROLE IN NEURAL DIFFERENTIATION AS WELL AS IN
NEURODEGENERATIVE DISORDERS
INDEX
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
NEURONAL TISSUE-NONSPECIFIC ALKALINE PHOSPHATASE (TNAP)
/
: 2015
ABSTRACT / INHALTSTEXT
PHOSPHATASES SUCH AS TNAP ARE FUNDAMENTAL IN REGULATING CELLULAR, AND
CONSEQUENTLY NUMEROUS BODY FUNCTIONS. TNAP IS A UBIQUITOUS ENZYME WITH A
WIDE SPECTRUM OF SUBSTRATES AND SPECIFICITY REGULATION AT THE CELLULAR
LEVEL AND THE LACK OF TNAP ACTIVITY IS A LETHAL CONDITION. RECENT
FINDINGS OF A HIGHLY SPECIFIC REGIONAL, LAMINAR AND SUBCELLULAR
LOCALIZATION OF TNAP IN THE CEREBRAL CORTEX INDICATES THAT IN ADDITION
TO ITS METABOLIC AND SKELETAL FUNCTIONS, TNAP ALSO PLAYS A ROLE IN
REGULATING CEREBRAL FUNCTIONS, MOST PROBABLY COGNITION. IN FACT, TNAP
DISTURBANCE COULD RESULT IN COMPLEX DISEASES SUCH AS EPILEPSY,
DEVELOPMENTAL RETARDATION AND ALZHEIMER DISEASE. AVAILABLE DATA SUGGEST
THAT, REGARDING BRAIN FUNCTIONS, TNAP IS A POTENTIALLY IMPORTANT TARGET
OF CLINICAL RESEARCH. THE PROPOSED BOOK AIMS TO PROVIDE AN OVERVIEW OF
OUR CURRENT UNDERSTANDING OF THE FUNCTIONS OF TNAP IN THE BRAIN
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
| any_adam_object | 1 |
| author2 | Fonta, Charlotte M. 1993- Négyessy, László |
| author2_role | edt edt |
| author2_variant | c m f cm cmf l n ln |
| author_GND | (DE-588)1253090912 |
| author_facet | Fonta, Charlotte M. 1993- Négyessy, László |
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| dewey-full | 612 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612 |
| dewey-search | 612 |
| dewey-sort | 3612 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| doi_str_mv | 10.1007/978-94-017-7197-9 |
| format | Electronic eBook |
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| indexdate | 2024-07-10T07:08:24Z |
| institution | BVB |
| isbn | 9789401771979 |
| language | English |
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| series | Subcellular biochemistry |
| series2 | Subcellular biochemistry |
| spelling | Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) Caroline Fonta, László Négyessy, editors Dordrecht Springer [2015] 1 Online-Ressource (xxii, 395 Seiten) Illustrationen txt rdacontent c rdamedia cr rdacarrier Subcellular biochemistry 76 Medicine Human physiology Neurosciences Developmental biology Animal Physiology Biomedicine Human Physiology Developmental Biology Medizin Nervensystem (DE-588)4041643-4 gnd rswk-swf Alkalische Phosphatase (DE-588)4141894-3 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Nervensystem (DE-588)4041643-4 s Alkalische Phosphatase (DE-588)4141894-3 s 2\p DE-604 Fonta, Charlotte M. 1993- (DE-588)1253090912 edt Négyessy, László edt Erscheint auch als Druck-Ausgabe, Hardcover 978-94-017-7196-2 Erscheint auch als Druck-Ausgabe, Paperback 978-94-024-0273-5 Subcellular biochemistry 76 (DE-604)BV041437497 76 https://doi.org/10.1007/978-94-017-7197-9 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028161507&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028161507&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) Subcellular biochemistry Medicine Human physiology Neurosciences Developmental biology Animal Physiology Biomedicine Human Physiology Developmental Biology Medizin Nervensystem (DE-588)4041643-4 gnd Alkalische Phosphatase (DE-588)4141894-3 gnd |
| subject_GND | (DE-588)4041643-4 (DE-588)4141894-3 (DE-588)4143413-4 |
| title | Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) |
| title_auth | Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) |
| title_exact_search | Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) |
| title_full | Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) Caroline Fonta, László Négyessy, editors |
| title_fullStr | Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) Caroline Fonta, László Négyessy, editors |
| title_full_unstemmed | Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) Caroline Fonta, László Négyessy, editors |
| title_short | Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP) |
| title_sort | neuronal tissue nonspecific alkaline phosphatase tnap |
| topic | Medicine Human physiology Neurosciences Developmental biology Animal Physiology Biomedicine Human Physiology Developmental Biology Medizin Nervensystem (DE-588)4041643-4 gnd Alkalische Phosphatase (DE-588)4141894-3 gnd |
| topic_facet | Medicine Human physiology Neurosciences Developmental biology Animal Physiology Biomedicine Human Physiology Developmental Biology Medizin Nervensystem Alkalische Phosphatase Aufsatzsammlung |
| url | https://doi.org/10.1007/978-94-017-7197-9 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028161507&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028161507&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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