Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2015
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| Schriftenreihe: | Methods in Pharmacology and Toxicology
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| Schlagworte: | |
| Online-Zugang: | TUM01 UBR01 Volltext Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource (XVIII, 375 p. 57 illus., 37 illus. in color) |
| ISBN: | 9781493926817 |
| ISSN: | 1557-2153 |
| DOI: | 10.1007/978-1-4939-2681-7 |
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Datensatz im Suchindex
| _version_ | 1804174933432991744 |
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| adam_text | MOLECULAR HISTOPATHOLOGY AND TISSUE BIOMARKERS IN DRUG AND DIAGNOSTIC
DEVELOPMENT
/
: 2015
TABLE OF CONTENTS / INHALTSVERZEICHNIS
HISTOPATHOLOGY: A CANVAS AND LANDSCAPE OF DISEASE IN DRUG AND DIAGNOSTIC
DEVELOPMENT
A FIELD GUIDE TO HOMO MORPHOLOGICUS FOR BIOMEDICAL SCIENTISTS, OR HOW TO
CONVEY AN UNDERSTANDING OF PATHOLOGY TO SCIENTISTS IN A BIOPHARMA
ENTERPRISE
OUTSOURCING TISSUE HISTOPATHOLOGY INVESTIGATIONS IN SUPPORT OF CLINICAL
TRIALS FOR NOVEL THERAPEUTICS: CONSIDERATIONS AND PERSPECTIVES
HISTOPATHOLOGY IN MOUSE MODELS OF RHEUMATOID ARTHRITIS
MARKERS USED FOR VISUALIZATION AND QUANTIFICATION OF BLOOD VESSELS AND
LYMPHATIC VESSELS
PRACTICAL APPROACHES TO MICROVESSEL ANALYSIS: HOTSPOTS, MICROVESSEL
DENSITY, AND VESSEL PROXIMITY
QUANTITATIVE HISTOPATHOLOGY AND ALTERNATIVE APPROACHES TO ASSESSMENT OF
FIBROSIS FOR DRUG DEVELOPMENT IN HEPATITIS C AND NONALCOHOLIC
STEATOHEPATITIS
STEREOLOGY AND COMPUTER-BASED IMAGE ANALYSIS QUANTIFIES HETEROGENEITY
AND IMPROVES REPRODUCIBILITY FOR GRADING RETICULIN IN MYELOPROLIFERATIVE
NEOPLASMS
IMAGE ANALYSIS TOOLS FOR QUANTIFICATION OF SPINAL MOTOR NEURON SUBTYPE
IDENTITIES
DEVELOPMENT OF A TISSUE IMAGE ANALYSIS ALGORITHM FOR CELIAC DRUG
DEVELOPMENT
QUANTITATIVE HISTOPATHOLOGY FOR EVALUATION OF IN VIVO BIOCOMPATIBILITY
ASSOCIATED WITH BIOMEDICAL IMPLANTS
QUANTITATIVE HISTOMORPHOMETRY AND QUANTITATIVE POLYMERASE CHAIN REACTION
(PCR) AS ASSESSMENT TOOLS FOR PRODUCT DEVELOPMENT
MEASURING THE MESSENGER: RNA HISTOLOGY IN FORMALIN FIXED TISSUES
ALGORITHM-DRIVEN IMAGE ANALYSIS SOLUTIONS FOR RNA ISH QUANTIFICATION IN
HUMAN CLINICAL TISSUES
SOLID TISSUE-BASED DNA ANALYSIS BY FISH IN RESEARCH AND MOLECULAR
DIAGNOSTICS
PREANALYTIC CONSIDERATIONS FOR MOLECULAR GENOMIC ANALYSES OF TISSUE
NEXT GENERATION SEQUENCING (NGS) IN ANATOMIC PATHOLOGY DISCOVERY AND
PRACTICE
THE IMPACT OF PRE-ANALYTIC VARIABLES ON TISSUE QUALITY FROM CLINICAL
SAMPLES COLLECTED IN A ROUTINE CLINICAL SETTING: IMPLICATIONS FOR
DIAGNOSTIC EVALUATION, DRUG DISCOVERY, AND TRANSLATIONAL RESEARCH
ADAPTING HER2 TESTING FOR A DIFFERENT ORGAN:NEW WINE IN OLD WINESKINS
TISSUE-BASED COMPANION DIAGNOSTICS: DEVELOPMENT OF IHC ASSAYS FROM AN
INDUSTRY PERSPECTIVE
DEVELOPMENT OF TISSUE-BASED COMPANION DIAGNOSTICS: THE RELATIONSHIP
BETWEEN THE PHARMACEUTICAL COMPANY, DIAGNOSTIC PARTNER, AND THE
BIOMARKER LABORATORY
NAVIGATING REGULATORY APPROVAL FOR TISSUE-BASED COMPANION DIAGNOSTICS
IMPLEMENTING A MULTI-ANALYTE IMMUNOHISTOCHEMISTRY PANEL INTO A DRUG
DEVELOPMENT PROGRAM
CUTPOINT ANALYSIS AND RELATED STATISTICAL METHODS IN DIGITAL PATHOLOGY
AND COMPANION DIAGNOSTICS
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
MOLECULAR HISTOPATHOLOGY AND TISSUE BIOMARKERS IN DRUG AND DIAGNOSTIC
DEVELOPMENT
/
: 2015
ABSTRACT / INHALTSTEXT
MOLECULAR HISTOPATHOLOGY AND TISSUE BIOMARKERS IN DRUG AND DIAGNOSTIC
DEVELOPMENT GATHERS DIVERSE EXPERTS TO PRESENT STATE OF THE ART GUIDANCE
AND APPLICATION OF HISTOPATHOLOGY IN DRUG DEVELOPMENT SETTINGS RANGING
FROM DISCOVERY RESEARCH TO HUMAN CLINICAL TRIALS. WHILE MANY CURRENT
APPLICATIONS OF QUANTITATIVE HISTOLOGY AND MOLECULAR PATHOLOGY IN THE
BIOPHARMACEUTICAL INDUSTRY ARE FOCUSED ON ONCOLOGY, THIS VOLUME IN
ADDITION EXPLORES NON-ONCOLOGIC DISEASE AREAS INCLUDING NONALCOHOLIC
STEATOHEPATITIS, ARTHRITIS, CELIAC DISEASE, MYELOPROLIFERATIVE
DISORDERS, NEUROLOGY, AND WOUND HEALING. THE AUTHORS WRITE FROM YEARS OF
EXPERIENCE IN DIAGNOSTIC PRACTICE AND PHARMACEUTICAL DRUG DEVELOPMENT,
AIMING TO EDUCATE PHARMACEUTICAL AND ACADEMIC SCIENTISTS HOW TO BEST USE
TISSUE TO DIAGNOSE DISEASE AND IMPROVE THE PROCESS OF DRUG
DEVELOPMENT. AS PART OF THE METHODS IN PHARMACOLOGY AND TOXICOLOGY
SERIES, THIS VOLUME IS DESIGNED TO PROVIDE WISDOM AND EXAMPLES THAT
OTHERS CAN FOLLOW AND APPLY AS PART OF DRUG DEVELOPMENT.
COMPREHENSIVE AND PRACTICAL, MOLECULAR HISTOPATHOLOGY AND TISSUE
BIOMARKERS IN DRUG AND DIAGNOSTIC DEVELOPMENT WILL INFORM AND ENLIGHTEN
BOTH TISSUE-FOCUSED AND NON-TISSUE-FOCUSED DRUG DEVELOPMENT
PROFESSIONALS ABOUT BETTER USE AND INTERPRETATION OF THE
MULTIDIMENSIONAL DATA CONTAINED IN A TISSUE BIOPSY
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| isbn | 9781493926817 |
| issn | 1557-2153 |
| language | English |
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| series2 | Methods in Pharmacology and Toxicology |
| spelling | Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development edited by Steven J. Potts, David A. Eberhard, Keith A. Wharton, Jr New York, NY Springer New York 2015 1 Online-Ressource (XVIII, 375 p. 57 illus., 37 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Pharmacology and Toxicology 1557-2153 Medicine Toxicology Biomedicine Pharmacology/Toxicology Medizin Potts, Steven J. Sonstige oth Eberhard, David A. Sonstige oth Wharton, Jr., Keith A. Sonstige oth Erscheint auch als Druckausgabe 978-1-4939-2680-0 https://doi.org/10.1007/978-1-4939-2681-7 Verlag Volltext http://www.springerprotocols.com/doiresolver?genre=book&pid=10.1007/978-1-4939-2681-7 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028156236&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028156236&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development Medicine Toxicology Biomedicine Pharmacology/Toxicology Medizin |
| title | Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development |
| title_auth | Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development |
| title_exact_search | Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development |
| title_full | Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development edited by Steven J. Potts, David A. Eberhard, Keith A. Wharton, Jr |
| title_fullStr | Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development edited by Steven J. Potts, David A. Eberhard, Keith A. Wharton, Jr |
| title_full_unstemmed | Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development edited by Steven J. Potts, David A. Eberhard, Keith A. Wharton, Jr |
| title_short | Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development |
| title_sort | molecular histopathology and tissue biomarkers in drug and diagnostic development |
| topic | Medicine Toxicology Biomedicine Pharmacology/Toxicology Medizin |
| topic_facet | Medicine Toxicology Biomedicine Pharmacology/Toxicology Medizin |
| url | https://doi.org/10.1007/978-1-4939-2681-7 http://www.springerprotocols.com/doiresolver?genre=book&pid=10.1007/978-1-4939-2681-7 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028156236&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028156236&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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