Photonics: scientific foundations, technology and applications 4 Biomedical photonics, spectroscopy and microscopy
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Hoboken, NJ
Wiley
2015
Science Wise Publ. 2015 |
| Online-Zugang: | Klappentext Inhaltsverzeichnis |
| Beschreibung: | XIV, 561 S. Ill., graph. Darst. |
| ISBN: | 9781118225554 |
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Datensatz im Suchindex
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|---|---|
| adam_text | CONTENTS
fl
List of Contributors ix
Preface • • ft
xm
1 Fluorescence 1
David J. S. Birch, Fw Chen, and OlafJ. Rolinski
1.1 Introduction, 1
1.2 Spectra, 2
1.3 Quantum Yield, 6
1.4 Lifetime, 12
1.5 Quenching, 23
1.6 Anisotropy, 30
1.7 Microscopy, 38
1.8 Conclusions, 48
Acknowledgments, 48
References, 49
2 Single-Molecule Detection and Spectroscopy 59
Michel Orrit
2.1 Introduction, 59
2.2 Experimental Setups, 62
2.3 Fluorescence Spectroscopy, 66
2.4 Fluorescence Correlation Spectroscopy, 72
2.5 Fluorescence Excitation Spectroscopy, 78
v
vi
CONTENTS
2.6 Other Detection Methods, 86
2.7 Conclusion, 93
Acknowledgments, 94
References, 94
3 Resonance Energy Transfer 101
David L. Andrews, David S. Bradshaw, Rayomond Dins haw, and Gregory D. Scholes
3.1 Introduction, 101
3.2 History of RET, 102
3.3 The Photophysics of RET, 103
3.4 Investigative Applications of RET in Molecular Biology, 113
3.5 The Role of RET in Light-Harvesting Complexes, 118
Acknowledgments, 122
References, 122
4 Biophotonics of Photosynthesis 129
Valter Zazubovich and Ryszard Jankowiak
4.1 Introduction, 129
4.2 Structure of Pigment-Protein Complexes and Structure—Function
Relationships, 130
4.3 Key Concepts in Physics of Pigment—Protein Complexes, 133
4.4 Experimental Techniques, 141
4.5 Examples, 145
4.6 Conclusions, 156
Acknowledgments, 157
References, 157
5 Optical Sectioning Microscopy and Biological Imaging 165
John Girkin
5.1 Introduction and Background, 165
5.2 Confocal Imaging, 168
5.3 Nonlinear Microscopy, 172
5.4 Practical Implementation of Nonlinear Microscopy, 181
5.5 Recent Advances in Nonlinear Microscopy, 184
5.6 Widefield Optical Sectioning by Specialized Illumination Methods, 186
5.7 Summary, 190
References, 191
6 Cell Handling, Sorting, and Viability 197
Darwin Palima, Thomas Aabo, Andrew Bañas, and Jesper Gliickstad
6.1 Handling Cells with Light, 198
6.2 Optical Sorting, 215
6.3 Cell Viability, 220
References, 230
CONTENTS
vii
7 Tissue Polarimetry
Alex Vitkin, Nirmalya Ghosh, and Antonello de Martino
7.1 Introduction, 239
7.2 Polarized Light Fundamentals, 240
7.3 Instrumentation, 266
7.4 Forward Modeling and Testing in Phantoms, 282
7.5 Applications, 297
7.6 Conclusions and Outlook, 313
References, 314
8 Optical Waveguide Biosensors
Daphné Duval and Laura M. Lechuga
8.1 Introduction, 323
8.2 Fundamentals of Label-Free Optical Waveguide Biosensing, 324
8.3 Surface Biofunctionalization, 328
8.4 Evaluation of Optical Biosensors, 331
8.5 Integrated Optical Waveguide-Based Biosensors, 334
8.6 Optical Fiber-Based Biosensors, 349
8.7 Lab-On-A-Chip Integration, 354
8.8 Summary, 357
References, 358
9 Light Propagation in Highly Scattering Thrbid Media: Concepts,
Techniques, and Biomedical Applications
R. R. Alfano, W B. Wang, L. Wang, and S. K. Gayen
9.1 Introduction, 367
9.2 Physics Behind Optical Imaging Through a Highly Scattering
Turbid Medium, 369
9.3 Study of Ballistic and Diffused Light Components, 378
9.4 Photon-Sorting Gates, 384
9.5 Transition From Ballistic to Diffuse Imaging in Turbid Media, 402
9.6 Conclusion, 404
Acknowledgments, 404
References, 404
10 Photodynamic Therapy
Rakkiyappan Chandran, Tyler G. St. Denis, Daniela Vecchio, Pinar Avci,
Magesh Sadasivam, and Michael R. Hamblin
10.1 Historical Overview of PDT, 413
10.2 Introduction to PDT, 415
10.3 Photosensitizer Structure and Photophysical Properties, 418
10.4 Light Dosimetry and Photodynamic Therapy Light Sources, 422
10.5 Light-Based Strategies to Enhance PDT, 423
10.6 PDT Targeting and Nanotechnology, 425
239
323
367
413
CONTENTS
10.7 PDT for Dermatology, 428
10.8 PDT for Oncology, 433
10.9 PDT for Infectious Disease, 435
10.10 PDT in Ophthalmology, 445
10.11 PDT and The Immune System, 446
10.12 Conclusion, 449
Acknowledgment, 449
References, 449
11 Imaging and Probing Cells Beyond the Optical Diffraction Limit
Mark Schiittpelz and Thomas Huser
11.1 The Quest for Achieving Optical Resolution Beyond
ABBE’S Limit, 469
11.2 Stimulated Emission Depletion Microscopy, 474
11.3 Photoactivated Localization Microscopy and Stochastic Optical
Reconstruction Microscopy, 477
11.4 Structured Illumination Microscopy, 483
11.5 Super-Resolution Optical Fluctuation Imaging and Other
Approaches, 491
11.6 Outlook, 495
Acknowledgments, 496
References, 497
12 Technology
Ann E. Eisner and Christopher A. Clark
12.1 Basic Ocular Anatomy and Physiology, 503
12.2 Measurement Techniques, 514
12.3 Anterior Segment Diagnostics, Refractive Measurements,
and Treatment, 522
12.4 Diagnostic Applications and Treatment of Posterior Segment, 529
References, 534
469
503
Index
543
Discusses the basic physical principles underlying biomedical
photonics, spectroscopy, and microscopy
This volume discusses biomedical photonics, spectroscopy, and
microscopy, the basic physical principles underlying the technology and
its applications. The topics discussed in this volume are: Fluorescence;
Single Molecule Detection and Spectroscopy; Resonance Energy Transfer;
Biophotonics oh Photosynthesis; Optical Sectioning Microscopy and
Biological Imagihg; Cell Handling and Sorting; Tissue Polarimetry; Optical
Waveguide Biosensors; Light Propagation in Highly Scattering Turbid
Media; Photodynamic Therapy; Imaging and Probing Cells beyond the
Diffraction Limit; and Ophthalmic Technology.
• Comprehensive and accessible coverage of the whole of
modern photonics
• Emphasizes processes and applications that specifically exploit
photon attributes of light
• Deals with the rapidly advancing area of modern optics
• Chapters are written by top scientists in their field
Written for the graduate-level student in physical sciences; industrial and
academic researchers in photonics, graduate students in the area; college
lecturers, educators, policymakers, consultants, scientific and technical
libraries, government laboratories, NIH.
DAVID L. ANDREWS leads research on fundamental molecular
photonics and energy transport, optomechanical forces, and nonlinear
optical phenomena. He has over 300 research papers and a dozen of
books to his name—including the widely adopted textbook, Lasers in
Chemistry.The current focus of his research group is on optical vortices,
novel mechanisms for optical nanomanipulation and switching, and light
harvesting in nanostructured molecular systems. The group enjoys strong
international links, particularly with groups in Canada, Lithuania, New
Zealand, and the United States. Andrews is a Fellow of the Royal Society
of Chemistry, a Fellow of the Institute of Physics, and a Fellow of SPIE, the
international society for optics and photonics.
ISBN 978-1-118-22555-4
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| spelling | Photonics scientific foundations, technology and applications 4 Biomedical photonics, spectroscopy and microscopy ed. by David L. Andrews Hoboken, NJ Wiley 2015 Science Wise Publ. 2015 XIV, 561 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Andrews, David L. 1952- Sonstige (DE-588)139421904 oth (DE-604)BV042624249 4 Digitalisierung UB Bayreuth - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028058291&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Klappentext Digitalisierung UB Bayreuth - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028058291&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Photonics scientific foundations, technology and applications |
| title | Photonics scientific foundations, technology and applications |
| title_auth | Photonics scientific foundations, technology and applications |
| title_exact_search | Photonics scientific foundations, technology and applications |
| title_full | Photonics scientific foundations, technology and applications 4 Biomedical photonics, spectroscopy and microscopy ed. by David L. Andrews |
| title_fullStr | Photonics scientific foundations, technology and applications 4 Biomedical photonics, spectroscopy and microscopy ed. by David L. Andrews |
| title_full_unstemmed | Photonics scientific foundations, technology and applications 4 Biomedical photonics, spectroscopy and microscopy ed. by David L. Andrews |
| title_short | Photonics |
| title_sort | photonics scientific foundations technology and applications biomedical photonics spectroscopy and microscopy |
| title_sub | scientific foundations, technology and applications |
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