The minipig in biomedical research:
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Boca Raton [u.a.]
CRC Press/Taylor & Francis
2012
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | "A CRC title." Includes bibliographical references and index |
| Beschreibung: | XVII, 643 S., [46] S. Ill. 29 cm |
| ISBN: | 9781439811184 1439811180 |
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| 300 | |a XVII, 643 S., [46] S. |b Ill. |c 29 cm | ||
| 336 | |b txt |2 rdacontent | ||
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| 650 | 7 | |a animal experiments |2 cabt | |
| 650 | 7 | |a animal models |2 cabt | |
| 650 | 4 | |a Animals, Laboratory | |
| 650 | 4 | |a Swine, Miniature | |
| 650 | 4 | |a Animal Welfare | |
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Datensatz im Suchindex
| _version_ | 1804174718456037376 |
|---|---|
| adam_text | Titel: The minipig in biomedical research
Autor: McAnulty, Peter A.
Jahr: 2012
Contents
Preface................................................................................................................................................................xi
Editors..............................................................................................................................................................xiii
Contributors......................................................................................................................................................xv
Section I
Origin and Management of the Minipig
Chapter 1
History and Development of Miniature, Micro- and Minipigs...............................................................................................3
Friederike Köhn
Chapter 2
Husbandry and Management..................................................................................................................................................17
Roberta Scipioni Ball
Chapter 3
Diseases of Minipigs..............................................................................................................................................................37
Nanna Grand
Chapter 4
International Transportation of Minipigs..............................................................................................................................69
Finn Raaschou-Nielsen
Section II
Welfare and Experimental Usage of the Minipig
Chapter 5
Ethical Issues in the Use of Minipigs in Animal Research...................................................................................................77
David Morton
Chapter 6
Animal Welfare Issues...........................................................................................................................................................85
Kathy E. Laber, Alison C. Smith and M. Michael Swindle
Chapter 7
Stress in Experiments: Stress Issues in Porcine Research.....................................................................................................93
Larry Dale Brown and Laust Peter Gade
Chapter 8
Dosing Methods....................................................................................................................................................................117
Peter Clausing
vi CONTENTS
Chapter 9
In-Life Clinical Observations..............................................................................................................................................127
David M. Cameron
Section III
Pharmacology and ADME Studies in the Minipig
Chapter 10
Minipigs in Absorption, Distribution, Metabolism, and Excretion (ADME) Studies..........................................................143
Cornelia Preuße and Mette Tingleff Skaanild
Chapter 11
The Minipig in Safety Pharmacology...................................................................................................................................159
Stephane Milano
Section IV
Safety Assessment in the Minipig-Principal Body Systems
Chapter 12
Dermal Toxicity Studies: Skin Architecture, Metabolism, Penetration and Toxicological
and Pharmacological Methods..............................................................................................................................................185
Andrew Makin, Jens Thing Mortensen and William J. Brock
Chapter 13
Gastrointestinal Tract............................................................................................................................................................211
Chris Van Ginneken
Chapter 14
Heart and Cardiotoxicity.....................................................................................................................................................237
James R. Turk
Chapter 15
Central and Peripheral Nervous Systems............................................................................................................................243
Allan Dahl Rasmussen and Karen Malene Wegener
Chapter 16
The Kidney...........................................................................................................................................................................253
Peter A. McAnulty
Chapter 17
Reproductive System Including Studies in Juvenile Minipigs.............................................................................................263
Peter A. McAnulty, Paul Barrow and Edward Marsden
CONTENTS vii
Chapter 18
The Endocrine System.........................................................................................................................................................277
Claudia Stark and Jakob Walter
Chapter 19
Skeletal System....................................................................................................................................................................283
Hideki Tsutsumi
Chapter 20
Ocular Examination and Background Observations...........................................................................................................293
Helmut Ehall
Chapter 21
Spontaneous/Background Pathology of Göttingen Minipig................................................................................................305
Zuhal Dincer and Mikala Skydsgaard
Section V
Genetics and Immunology
Chapter 22
A Comparative Assessment of the Pig, Mouse and Human Genomes: Structural and Functional Analysis
of Genes Involved in Immunity and Inflammation.............................................................................................................323
Harry D. Dawson
Chapter 23
The Immune System of Pigs: Structure and Function.........................................................................................................343
Patrick Haley
Chapter 24
Transplantation in Miniature Swine.....................................................................................................................................357
John S. Hanekamp, Raimon Duran-Struuck and David H. Sachs
Chapter 25
Xenotransplantation..............................................................................................................................................................373
Henk-Jan Schuurman, Melanie L. Graham, Thomas Spizzo, and Clive Patience
Chapter 26
Porcine Endogenous Retroviruses in Xenotransplantation: A Review of the Importance of PERVs in Porcine
Studies, with Particular Emphasis on the Minipig..............................................................................................................387
Linda Scobie and Olga Garkavenko
Chapter 27
Immunotoxicology: Studies in the Minipig.........................................................................................................................397
André H. Penninks and Geertje J.D. van Mierlo
vüi CONTENTS
Section VI
Disease Models
Chapter 28
Creation and Conservation of Genetically Modified Pigs: Applications to Genetic Disease Model
and Xenotransplantation.......................................................................................................................................................415
Hiroshi Nagashima, Hitomi Matsunari, and Kazuhiro Umeyama
Chapter 29
Stem Cell Research and Minipigs.........................................................................................................................................431
Vanessa J. Hall, Stoyan G. Petkov, and Poul Hyttel
Chapter 30
Minipig Models of Diabetes Mellitus..................................................................................................................................445
Dwight A. Bellinger, Elizabeth P. Merricks, and Timothy C. Nichols
Chapter 31
Minipig in Biomedical Research: Diet-Induced Atherosclerosis........................................................................................469
James R. Turk and M. Harold Laughlin
Chapter 32
Hemorrhage and Resuscitation Models Using the Miniature Swine....................................................................................479
John W. Burns and Charles E. Wade
Chapter 33
Oral Biology and Dental Models..........................................................................................................................................491
Susan W. Herring, Yiming Li, Yi Liu, Zi Jun Liu, Tracy E. Popowics,
Katherine L. Rafferty, and Songlin Wang
Chapter 34
Osteoporosis Model in Minipigs...........................................................................................................................................517
Hideki Tsutsumi, Satoshi Ikeda, and Toshitaka Nakamura
Chapter 35
Wound Healing Models.......................................................................................................................................................525
Peter Glerup
Chapter 36
The Minipig in Chemical, Biological, and Radiological Research......................................................................................533
Stanley W. Hulet, Maria Moroni, Mark H. Whitnall, and Robert J. Mioduszewski
Chapter 37
The Minipig and Pig in Medical Device Research...........................................................................................................549
Shayne C. Gad
CONTENTS ix
Section VII
Regulatory Perspective and Use of the Minipig in Developing Marketed Products
Chapter 38
Regulatory Aspects: Pharmaceuticals, Medical Devices, Food Additives: Minipigs and Global Safety Regulations.......565
Abigail Jacobs and Jan-Willem van der Laan
Chapter 39
Adverse Responses to Drugs in Man: Critical Comparison of Reported Toxicological
Findings in Minipigs and Humans.......................................................................................................................................573
Niels-Christian Ganderup
Chapter 40
Regulatory Acceptance of the Minipig in Non-Pharmaceutical Industry and Research....................................................595
Warren Harvey
Section VIII
New Horizons and perspectives
Chapter 41
Future Prospects: Possibilities and Perspectives..................................................................................................................619
Anthony D. Dayan
Index....................................................................................................................................................................................627
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| id | DE-604.BV042567447 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T07:04:51Z |
| institution | BVB |
| isbn | 9781439811184 1439811180 |
| language | English |
| lccn | 2011039677 |
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| spelling | The minipig in biomedical research edited by Peter A. McAnulty ... Boca Raton [u.a.] CRC Press/Taylor & Francis 2012 XVII, 643 S., [46] S. Ill. 29 cm txt rdacontent n rdamedia nc rdacarrier "A CRC title." Includes bibliographical references and index miniature pigs cabt animal experiments cabt animal models cabt Animals, Laboratory Swine, Miniature Animal Welfare Biomedical Research methods Disease Models, Animal McAnulty, Peter A. (DE-588)1019645105 edt HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028001065&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | The minipig in biomedical research miniature pigs cabt animal experiments cabt animal models cabt Animals, Laboratory Swine, Miniature Animal Welfare Biomedical Research methods Disease Models, Animal |
| title | The minipig in biomedical research |
| title_auth | The minipig in biomedical research |
| title_exact_search | The minipig in biomedical research |
| title_full | The minipig in biomedical research edited by Peter A. McAnulty ... |
| title_fullStr | The minipig in biomedical research edited by Peter A. McAnulty ... |
| title_full_unstemmed | The minipig in biomedical research edited by Peter A. McAnulty ... |
| title_short | The minipig in biomedical research |
| title_sort | the minipig in biomedical research |
| topic | miniature pigs cabt animal experiments cabt animal models cabt Animals, Laboratory Swine, Miniature Animal Welfare Biomedical Research methods Disease Models, Animal |
| topic_facet | miniature pigs animal experiments animal models Animals, Laboratory Swine, Miniature Animal Welfare Biomedical Research methods Disease Models, Animal |
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