Consanguinity, Inbreeding, and Genetic Drift in Italy:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Princeton, N.J.
Princeton University Press
[2004]
|
| Schriftenreihe: | Monographs in Population Biology
39 |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | In 1951, the geneticist Luigi Luca Cavalli-Sforza was teaching in Parma when a student--a priest named Antonio Moroni--told him about rich church records of demography and marriages between relatives. After convincing the Church to open its records, Cavalli-Sforza, Moroni, and Gianna Zei embarked on a landmark study that would last fifty years and cover all of Italy. This book assembles and analyzes the team's research for the first time. Using blood testing as well as church records, the team investigated the frequency of consanguineous marriages and its use for estimating inbreeding and studying the relations between inbreeding and drift. They tested the importance of random genetic drift by studying population structure through demography of the last three centuries, using it to predict the spatial variation of frequencies of genetic markers. The authors find that drift-related genetic variation, including its stabilization by migration, is best predicted by computer simulation. They also analyze the usefulness and limits of the concept of deme for defining Mendelian populations. The genetic effect of consanguineous marriage on recessive genetic diseases and for the detection of dominance in metric characters are also studied. Ultimately bringing together the many strands of their massive project, Cavalli-Sforza, Moroni, and Zei are able to map genetic drift in all of Italy's approximately 8,000 communes and to demonstrate the relationship between each locality's drift and various ecological and demographic factors. In terms of both methods and findings, their accomplishment is tremendously important for understanding human social structure and the genetic effects of drift and inbreeding |
| Beschreibung: | 1 Online-Ressource (328p.) |
| ISBN: | 9781400847273 |
| DOI: | 10.1515/9781400847273 |
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| 500 | |a In 1951, the geneticist Luigi Luca Cavalli-Sforza was teaching in Parma when a student--a priest named Antonio Moroni--told him about rich church records of demography and marriages between relatives. After convincing the Church to open its records, Cavalli-Sforza, Moroni, and Gianna Zei embarked on a landmark study that would last fifty years and cover all of Italy. This book assembles and analyzes the team's research for the first time. Using blood testing as well as church records, the team investigated the frequency of consanguineous marriages and its use for estimating inbreeding and studying the relations between inbreeding and drift. They tested the importance of random genetic drift by studying population structure through demography of the last three centuries, using it to predict the spatial variation of frequencies of genetic markers. The authors find that drift-related genetic variation, including its stabilization by migration, is best predicted by computer simulation. They also analyze the usefulness and limits of the concept of deme for defining Mendelian populations. The genetic effect of consanguineous marriage on recessive genetic diseases and for the detection of dominance in metric characters are also studied. Ultimately bringing together the many strands of their massive project, Cavalli-Sforza, Moroni, and Zei are able to map genetic drift in all of Italy's approximately 8,000 communes and to demonstrate the relationship between each locality's drift and various ecological and demographic factors. In terms of both methods and findings, their accomplishment is tremendously important for understanding human social structure and the genetic effects of drift and inbreeding | ||
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Datensatz im Suchindex
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| author | Cavalli-Sforza, Luigi L. 1922-2018 |
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| dewey-tens | 300 - Social sciences |
| discipline | Soziologie |
| doi_str_mv | 10.1515/9781400847273 |
| era | Geschichte gnd |
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| geographic_facet | Italien |
| id | DE-604.BV042523103 |
| illustrated | Not Illustrated |
| indexdate | 2025-01-02T19:18:20Z |
| institution | BVB |
| isbn | 9781400847273 |
| language | English |
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| publishDate | 2004 |
| publishDateSearch | 2004 |
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| publisher | Princeton University Press |
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| series2 | Monographs in Population Biology |
| spelling | Cavalli-Sforza, Luigi L. 1922-2018 Verfasser (DE-588)115744312 aut Consanguinity, Inbreeding, and Genetic Drift in Italy Luigi Luca Cavalli-Sforza, Antonio Moroni, Gianna Zei Princeton, N.J. Princeton University Press [2004] 1 Online-Ressource (328p.) txt rdacontent c rdamedia cr rdacarrier Monographs in Population Biology 39 In 1951, the geneticist Luigi Luca Cavalli-Sforza was teaching in Parma when a student--a priest named Antonio Moroni--told him about rich church records of demography and marriages between relatives. After convincing the Church to open its records, Cavalli-Sforza, Moroni, and Gianna Zei embarked on a landmark study that would last fifty years and cover all of Italy. This book assembles and analyzes the team's research for the first time. Using blood testing as well as church records, the team investigated the frequency of consanguineous marriages and its use for estimating inbreeding and studying the relations between inbreeding and drift. They tested the importance of random genetic drift by studying population structure through demography of the last three centuries, using it to predict the spatial variation of frequencies of genetic markers. The authors find that drift-related genetic variation, including its stabilization by migration, is best predicted by computer simulation. They also analyze the usefulness and limits of the concept of deme for defining Mendelian populations. The genetic effect of consanguineous marriage on recessive genetic diseases and for the detection of dominance in metric characters are also studied. Ultimately bringing together the many strands of their massive project, Cavalli-Sforza, Moroni, and Zei are able to map genetic drift in all of Italy's approximately 8,000 communes and to demonstrate the relationship between each locality's drift and various ecological and demographic factors. In terms of both methods and findings, their accomplishment is tremendously important for understanding human social structure and the genetic effects of drift and inbreeding In English Geschichte gnd rswk-swf Sozialwissenschaften, Soziologie, Anthropologie Conganguinity / Italy Inbreeding / Italy Human population genetics / Italy Human genetics / Variation SOCIAL SCIENCE / Demography bisacsh SCIENCE / Life Sciences / Biology bisacsh Genetic Drift / Italy Consanguinity / Italy Genetics, Population / Italy Genotype / Italy Gendrift (DE-588)4357334-4 gnd rswk-swf Blutsverwandtschaft (DE-588)4133956-3 gnd rswk-swf Italien Italien (DE-588)4027833-5 gnd rswk-swf Italien (DE-588)4027833-5 g Blutsverwandtschaft (DE-588)4133956-3 s Gendrift (DE-588)4357334-4 s Geschichte z 1\p DE-604 Moroni, Antonio Sonstige oth Zei, Gianna Sonstige oth https://doi.org/10.1515/9781400847273 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Cavalli-Sforza, Luigi L. 1922-2018 Consanguinity, Inbreeding, and Genetic Drift in Italy Sozialwissenschaften, Soziologie, Anthropologie Conganguinity / Italy Inbreeding / Italy Human population genetics / Italy Human genetics / Variation SOCIAL SCIENCE / Demography bisacsh SCIENCE / Life Sciences / Biology bisacsh Genetic Drift / Italy Consanguinity / Italy Genetics, Population / Italy Genotype / Italy Gendrift (DE-588)4357334-4 gnd Blutsverwandtschaft (DE-588)4133956-3 gnd |
| subject_GND | (DE-588)4357334-4 (DE-588)4133956-3 (DE-588)4027833-5 |
| title | Consanguinity, Inbreeding, and Genetic Drift in Italy |
| title_auth | Consanguinity, Inbreeding, and Genetic Drift in Italy |
| title_exact_search | Consanguinity, Inbreeding, and Genetic Drift in Italy |
| title_full | Consanguinity, Inbreeding, and Genetic Drift in Italy Luigi Luca Cavalli-Sforza, Antonio Moroni, Gianna Zei |
| title_fullStr | Consanguinity, Inbreeding, and Genetic Drift in Italy Luigi Luca Cavalli-Sforza, Antonio Moroni, Gianna Zei |
| title_full_unstemmed | Consanguinity, Inbreeding, and Genetic Drift in Italy Luigi Luca Cavalli-Sforza, Antonio Moroni, Gianna Zei |
| title_short | Consanguinity, Inbreeding, and Genetic Drift in Italy |
| title_sort | consanguinity inbreeding and genetic drift in italy |
| topic | Sozialwissenschaften, Soziologie, Anthropologie Conganguinity / Italy Inbreeding / Italy Human population genetics / Italy Human genetics / Variation SOCIAL SCIENCE / Demography bisacsh SCIENCE / Life Sciences / Biology bisacsh Genetic Drift / Italy Consanguinity / Italy Genetics, Population / Italy Genotype / Italy Gendrift (DE-588)4357334-4 gnd Blutsverwandtschaft (DE-588)4133956-3 gnd |
| topic_facet | Sozialwissenschaften, Soziologie, Anthropologie Conganguinity / Italy Inbreeding / Italy Human population genetics / Italy Human genetics / Variation SOCIAL SCIENCE / Demography SCIENCE / Life Sciences / Biology Genetic Drift / Italy Consanguinity / Italy Genetics, Population / Italy Genotype / Italy Gendrift Blutsverwandtschaft Italien |
| url | https://doi.org/10.1515/9781400847273 |
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