Kinesins and Cancer:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Dordrecht [u.a.]
Springer
2015
|
| Schlagworte: | |
| Online-Zugang: | TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource (X, 271 p. 50 illus., 32 illus. in color) |
| ISBN: | 9789401797320 |
| DOI: | 10.1007/978-94-017-9732-0 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV042482261 | ||
| 003 | DE-604 | ||
| 005 | 20150410 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 150402s2015 |||| o||u| ||||||eng d | ||
| 020 | |a 9789401797320 |c Online |9 978-94-017-9732-0 | ||
| 024 | 7 | |a 10.1007/978-94-017-9732-0 |2 doi | |
| 035 | |a (OCoLC)1075514584 | ||
| 035 | |a (DE-599)BVBBV042482261 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-91 |a DE-703 | ||
| 082 | 0 | |a 614.5999 |2 23 | |
| 084 | |a BIO 000 |2 stub | ||
| 245 | 1 | 0 | |a Kinesins and Cancer |c Frank Kozielski, ed. |
| 264 | 1 | |a Dordrecht [u.a.] |b Springer |c 2015 | |
| 300 | |a 1 Online-Ressource (X, 271 p. 50 illus., 32 illus. in color) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 650 | 4 | |a Medicine | |
| 650 | 4 | |a Oncology | |
| 650 | 4 | |a Biochemistry | |
| 650 | 4 | |a RNA-ligand interactions | |
| 650 | 4 | |a Cytology | |
| 650 | 4 | |a Biomedicine | |
| 650 | 4 | |a Cancer Research | |
| 650 | 4 | |a Cell Biology | |
| 650 | 4 | |a Medicinal Chemistry | |
| 650 | 4 | |a Protein-Ligand Interactions | |
| 650 | 4 | |a Medizin | |
| 700 | 1 | |a Kozielski, Frank |e Sonstige |4 oth | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druckausgabe |z 978-94-017-9731-3 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-94-017-9732-0 |x Verlag |3 Volltext |
| 856 | 4 | 2 | |m Springer Fremddatenuebernahme |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027917220&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 856 | 4 | 2 | |m Springer Fremddatenuebernahme |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027917220&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |3 Abstract |
| 912 | |a ZDB-2-SBL | ||
| 940 | 1 | |q ZDB-2-SBL_2015 | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-027917220 | ||
| 966 | e | |u https://doi.org/10.1007/978-94-017-9732-0 |l TUM01 |p ZDB-2-SBL |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1007/978-94-017-9732-0 |l UBT01 |p ZDB-2-SBL |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804153212527181824 |
|---|---|
| adam_text | KINESINS AND CANCER
/ KOZIELSKI, FSB, FRANK
: 2015
TABLE OF CONTENTS / INHALTSVERZEICHNIS
PREFACE
THE KINESIN SUPERFAMILY
THE DISCOVERY AND DEVELOPMENT OF EG5 INHIBITORS FOR THE CLINIC
MECHANISM OF ACTION OF EG5 INHIBITORS
CLINICAL TRIALS OF MITOTIC KINESIN INHIBITORS
KIF15; A USEFUL TARGET FOR ANTI-CANCER THERAPY?.-DOWN-REGULATING
CENP-E ACTIVITY: FOR BETTER OR FOR WORSE
THE HUMAN KINESIN-14 MOTOR KIFC1/HSET IS AN ATTRACTIVE ANTI-CANCER DRUG
TARGET.-KINESIN-13 MICROTUBULE DEPOLYMERIZING PROTEINS AS TARGETS FOR
CANCER THERAPY
CHROMOKINESINS IN GENOME MAINTENANCE AND CANCER
KIF14: A CLINICALLY RELEVANT KINESIN AND POTENTIAL TARGET FOR CANCER
THERAPY
KINESIN-8 MEMBERS AND THEIR POTENTIAL AS BIOMARKER OR THERAPEUTIC TARGET
THE KINESIN-6 MEMBERS MKLP1, MKLP2 AND MPP
NON-MOTOR SPINDLE PROTEINS AS CANCER CHEMOTHERAPY TARGETS
INHIBITORS OF MITOTIC KINESINS FOR CANCER TREATMENT: CONSEQUENCES FOR
NEURONS
INDEX
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
KINESINS AND CANCER
/ KOZIELSKI, FSB, FRANK
: 2015
ABSTRACT / INHALTSTEXT
THIS INTERDISCIPLINARY VOLUME COLLATES RESEARCH WORK ON KINESINS AND
CANCER. AUTHORS ATTEMPT TO VALIDATE MEMBERS OF THE KINESIN SUPERFAMILY
AS POTENTIAL TARGETS FOR DRUG DEVELOPMENT IN CANCER CHEMOTHERAPY. THE
WORK BEGINS BY HIGHLIGHTING THE IMPORTANCE OF KINESINS, SUMMARISING
CURRENT KNOWLEDGE AND HOW THEY ARE SHOWN TO BE CRUCIAL FOR MITOSIS.
CHAPTERS GO ON TO EXPLORE HOW THIS FAMILY OF PROTEINS ARE EMERGING AS A
NOVEL TARGET FOR CHEMOTHERAPEUTIC INTERVENTION AND DRUG DEVELOPMENT.
READERS WILL LEARN HOW KINESINS TRAVEL ALONG MICROTUBULES TO FULFILL
THEIR MANY ROLES IN INTRACELLULAR TRANSPORT OR CELL DIVISION. SEVERAL
COMPOUNDS THAT INHIBIT TWO MITOTIC KINESINS (CALLED EG5 AND CENP-E) HAVE
ENTERED PHASE I AND II CLINICAL TRIALS AND ARE EXPLORED IN THESE
CHAPTERS. ADDITIONAL MITOTIC KINESINS ARE CURRENTLY BEING VALIDATED AS
DRUG TARGETS, RAISING THE POSSIBILITY THAT THE REPERTOIRE OF
KINESIN-BASED DRUG TARGETS MAY EXPAND IN THE FUTURE. THE BOOK IS
SUITABLE AS A REFERENCE STANDARD FOR THE FIELD OF KINESINS AND CANCER.
IT WILL INTEREST THOSE IN ACADEMIA AND PHARMACEUTICAL COMPANIES, AND
ANYONE WITH AN INTEREST IN THE MEDICAL RELEVANCE OF THESE PROTEINS,
WHICH CUTTING EDGE METHODOLOGIES ARE NOW ENABLING US TO UNDERSTAND IN
ASTONISHING DETAIL
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV042482261 |
| classification_tum | BIO 000 |
| collection | ZDB-2-SBL |
| ctrlnum | (OCoLC)1075514584 (DE-599)BVBBV042482261 |
| dewey-full | 614.5999 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 614 - Forensic medicine; incidence of disease |
| dewey-raw | 614.5999 |
| dewey-search | 614.5999 |
| dewey-sort | 3614.5999 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| doi_str_mv | 10.1007/978-94-017-9732-0 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02102nmm a2200517zc 4500</leader><controlfield tag="001">BV042482261</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20150410 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">150402s2015 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9789401797320</subfield><subfield code="c">Online</subfield><subfield code="9">978-94-017-9732-0</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-94-017-9732-0</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1075514584</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV042482261</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-91</subfield><subfield code="a">DE-703</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">614.5999</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">BIO 000</subfield><subfield code="2">stub</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Kinesins and Cancer</subfield><subfield code="c">Frank Kozielski, ed.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Dordrecht [u.a.]</subfield><subfield code="b">Springer</subfield><subfield code="c">2015</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (X, 271 p. 50 illus., 32 illus. in color)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Oncology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biochemistry</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">RNA-ligand interactions</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cytology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biomedicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cancer Research</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cell Biology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medicinal Chemistry</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Protein-Ligand Interactions</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medizin</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kozielski, Frank</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druckausgabe</subfield><subfield code="z">978-94-017-9731-3</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-94-017-9732-0</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Springer Fremddatenuebernahme</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027917220&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Springer Fremddatenuebernahme</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027917220&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Abstract</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-SBL</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">ZDB-2-SBL_2015</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-027917220</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-94-017-9732-0</subfield><subfield code="l">TUM01</subfield><subfield code="p">ZDB-2-SBL</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-94-017-9732-0</subfield><subfield code="l">UBT01</subfield><subfield code="p">ZDB-2-SBL</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV042482261 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:23:01Z |
| institution | BVB |
| isbn | 9789401797320 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027917220 |
| oclc_num | 1075514584 |
| open_access_boolean | |
| owner | DE-91 DE-BY-TUM DE-703 |
| owner_facet | DE-91 DE-BY-TUM DE-703 |
| physical | 1 Online-Ressource (X, 271 p. 50 illus., 32 illus. in color) |
| psigel | ZDB-2-SBL ZDB-2-SBL_2015 |
| publishDate | 2015 |
| publishDateSearch | 2015 |
| publishDateSort | 2015 |
| publisher | Springer |
| record_format | marc |
| spelling | Kinesins and Cancer Frank Kozielski, ed. Dordrecht [u.a.] Springer 2015 1 Online-Ressource (X, 271 p. 50 illus., 32 illus. in color) txt rdacontent c rdamedia cr rdacarrier Medicine Oncology Biochemistry RNA-ligand interactions Cytology Biomedicine Cancer Research Cell Biology Medicinal Chemistry Protein-Ligand Interactions Medizin Kozielski, Frank Sonstige oth Erscheint auch als Druckausgabe 978-94-017-9731-3 https://doi.org/10.1007/978-94-017-9732-0 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027917220&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027917220&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Kinesins and Cancer Medicine Oncology Biochemistry RNA-ligand interactions Cytology Biomedicine Cancer Research Cell Biology Medicinal Chemistry Protein-Ligand Interactions Medizin |
| title | Kinesins and Cancer |
| title_auth | Kinesins and Cancer |
| title_exact_search | Kinesins and Cancer |
| title_full | Kinesins and Cancer Frank Kozielski, ed. |
| title_fullStr | Kinesins and Cancer Frank Kozielski, ed. |
| title_full_unstemmed | Kinesins and Cancer Frank Kozielski, ed. |
| title_short | Kinesins and Cancer |
| title_sort | kinesins and cancer |
| topic | Medicine Oncology Biochemistry RNA-ligand interactions Cytology Biomedicine Cancer Research Cell Biology Medicinal Chemistry Protein-Ligand Interactions Medizin |
| topic_facet | Medicine Oncology Biochemistry RNA-ligand interactions Cytology Biomedicine Cancer Research Cell Biology Medicinal Chemistry Protein-Ligand Interactions Medizin |
| url | https://doi.org/10.1007/978-94-017-9732-0 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027917220&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027917220&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT kozielskifrank kinesinsandcancer |