Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | German |
| Veröffentlicht: |
Vienna
Springer Vienna
1963
|
| Schriftenreihe: | Fortschritte Der Chemie Organischer Naturstoffe
21 |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | During the early 1950's there appeared reports, from time to time of the presence among the products elaborated by actinomycetes of antifungal antibiotics which exhibited very similar and very characteristic multipeaked ultraviolet absorption spectra. In 1954, with a good number of examples on record, these spectra were analyzed and identified as those of straight-chain conjugated polyenes, comprising tetraenes, pentaenes, hexaenes and heptaenes (85, I30). These antibiotics have since been commonly referred to as the polyene antifungal antibiotics to distinguish them from a host of other miscellaneous antibiotics which also have antifungal properties. Within the next few years, reports of discoveries of new members of this class multiplied rapidly, and almost sixty are now known. Unquestionably, a number of these will eventually be found to be identical with others, as has already happened in several instances: for example, the tetraene "tennecetin" proved to be a rediscovery of pimaricin (34), and in the methyl pentaenes "moldcidin E" has been identified with pentamycin (83), and "lagosin" appears to be indistinguishable from fungichromin (22). Those that have been purified have turned out to be of fairly high molecular weight (ca. 700-1300) and all appear to be substances of rather similar molecular structure. So far only three, pimaricin, fungi chromin (lagosin) and filipin, have been structurally elucidated |
| Beschreibung: | 1 Online-Ressource (VIII, 364 S. 2 Abb) |
| ISBN: | 9783709171493 9783709171509 |
| ISSN: | 0071-7886 |
| DOI: | 10.1007/978-3-7091-7149-3 |
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| 245 | 1 | 0 | |a Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles |c von R. Bangert, J. Bonner, H. Brockmann, L. Crombie, L. Jaenicke, C. Kutzbach, A. D. Mebane, H. Muxfeldt, W. Oroshnik ; herausgegeben von L. Zechmeister |
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| 500 | |a During the early 1950's there appeared reports, from time to time of the presence among the products elaborated by actinomycetes of antifungal antibiotics which exhibited very similar and very characteristic multipeaked ultraviolet absorption spectra. In 1954, with a good number of examples on record, these spectra were analyzed and identified as those of straight-chain conjugated polyenes, comprising tetraenes, pentaenes, hexaenes and heptaenes (85, I30). These antibiotics have since been commonly referred to as the polyene antifungal antibiotics to distinguish them from a host of other miscellaneous antibiotics which also have antifungal properties. Within the next few years, reports of discoveries of new members of this class multiplied rapidly, and almost sixty are now known. Unquestionably, a number of these will eventually be found to be identical with others, as has already happened in several instances: for example, the tetraene "tennecetin" proved to be a rediscovery of pimaricin (34), and in the methyl pentaenes "moldcidin E" has been identified with pentamycin (83), and "lagosin" appears to be indistinguishable from fungichromin (22). Those that have been purified have turned out to be of fairly high molecular weight (ca. 700-1300) and all appear to be substances of rather similar molecular structure. So far only three, pimaricin, fungi chromin (lagosin) and filipin, have been structurally elucidated | ||
| 650 | 4 | |a Chemistry | |
| 650 | 4 | |a Toxicology | |
| 650 | 4 | |a Chemistry, Organic | |
| 650 | 4 | |a Pharmacy | |
| 650 | 4 | |a Biochemistry | |
| 650 | 4 | |a Botany | |
| 650 | 4 | |a Organic Chemistry | |
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| 650 | 4 | |a Pharmacology/Toxicology | |
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| 700 | 1 | |a Oroshnik, W. |e Sonstige |4 oth | |
| 700 | 1 | |a Zechmeister, L. |e Sonstige |4 oth | |
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Datensatz im Suchindex
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| author | Bangert, R. |
| author_facet | Bangert, R. |
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| author_sort | Bangert, R. |
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| dewey-full | 547 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 547 - Organic chemistry |
| dewey-raw | 547 |
| dewey-search | 547 |
| dewey-sort | 3547 |
| dewey-tens | 540 - Chemistry and allied sciences |
| discipline | Chemie / Pharmazie Allgemeine Naturwissenschaft |
| doi_str_mv | 10.1007/978-3-7091-7149-3 |
| format | Electronic eBook |
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| id | DE-604.BV042452919 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:22:09Z |
| institution | BVB |
| isbn | 9783709171493 9783709171509 |
| issn | 0071-7886 |
| language | German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027888165 |
| oclc_num | 863794937 |
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| physical | 1 Online-Ressource (VIII, 364 S. 2 Abb) |
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| publishDate | 1963 |
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| publisher | Springer Vienna |
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| series2 | Fortschritte Der Chemie Organischer Naturstoffe |
| spelling | Bangert, R. Verfasser aut Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles von R. Bangert, J. Bonner, H. Brockmann, L. Crombie, L. Jaenicke, C. Kutzbach, A. D. Mebane, H. Muxfeldt, W. Oroshnik ; herausgegeben von L. Zechmeister Vienna Springer Vienna 1963 1 Online-Ressource (VIII, 364 S. 2 Abb) txt rdacontent c rdamedia cr rdacarrier Fortschritte Der Chemie Organischer Naturstoffe 21 0071-7886 During the early 1950's there appeared reports, from time to time of the presence among the products elaborated by actinomycetes of antifungal antibiotics which exhibited very similar and very characteristic multipeaked ultraviolet absorption spectra. In 1954, with a good number of examples on record, these spectra were analyzed and identified as those of straight-chain conjugated polyenes, comprising tetraenes, pentaenes, hexaenes and heptaenes (85, I30). These antibiotics have since been commonly referred to as the polyene antifungal antibiotics to distinguish them from a host of other miscellaneous antibiotics which also have antifungal properties. Within the next few years, reports of discoveries of new members of this class multiplied rapidly, and almost sixty are now known. Unquestionably, a number of these will eventually be found to be identical with others, as has already happened in several instances: for example, the tetraene "tennecetin" proved to be a rediscovery of pimaricin (34), and in the methyl pentaenes "moldcidin E" has been identified with pentamycin (83), and "lagosin" appears to be indistinguishable from fungichromin (22). Those that have been purified have turned out to be of fairly high molecular weight (ca. 700-1300) and all appear to be substances of rather similar molecular structure. So far only three, pimaricin, fungi chromin (lagosin) and filipin, have been structurally elucidated Chemistry Toxicology Chemistry, Organic Pharmacy Biochemistry Botany Organic Chemistry Biochemistry, general Pharmacology/Toxicology Plant Sciences Chemie Bonner, J. Sonstige oth Brockmann, H. Sonstige oth Crombie, L. Sonstige oth Jaenicke, L. Sonstige oth Kutzbach, C. Sonstige oth Mebane, A. D. Sonstige oth Muxfeldt, H. Sonstige oth Oroshnik, W. Sonstige oth Zechmeister, L. Sonstige oth https://doi.org/10.1007/978-3-7091-7149-3 Verlag Volltext |
| spellingShingle | Bangert, R. Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles Chemistry Toxicology Chemistry, Organic Pharmacy Biochemistry Botany Organic Chemistry Biochemistry, general Pharmacology/Toxicology Plant Sciences Chemie |
| title | Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles |
| title_auth | Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles |
| title_exact_search | Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles |
| title_full | Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles von R. Bangert, J. Bonner, H. Brockmann, L. Crombie, L. Jaenicke, C. Kutzbach, A. D. Mebane, H. Muxfeldt, W. Oroshnik ; herausgegeben von L. Zechmeister |
| title_fullStr | Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles von R. Bangert, J. Bonner, H. Brockmann, L. Crombie, L. Jaenicke, C. Kutzbach, A. D. Mebane, H. Muxfeldt, W. Oroshnik ; herausgegeben von L. Zechmeister |
| title_full_unstemmed | Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles von R. Bangert, J. Bonner, H. Brockmann, L. Crombie, L. Jaenicke, C. Kutzbach, A. D. Mebane, H. Muxfeldt, W. Oroshnik ; herausgegeben von L. Zechmeister |
| title_short | Progress in the Chemistry of Organic Natural Products/Progrès Dans La Chimie Des Substances Organiques Naturelles |
| title_sort | progress in the chemistry of organic natural products progres dans la chimie des substances organiques naturelles |
| topic | Chemistry Toxicology Chemistry, Organic Pharmacy Biochemistry Botany Organic Chemistry Biochemistry, general Pharmacology/Toxicology Plant Sciences Chemie |
| topic_facet | Chemistry Toxicology Chemistry, Organic Pharmacy Biochemistry Botany Organic Chemistry Biochemistry, general Pharmacology/Toxicology Plant Sciences Chemie |
| url | https://doi.org/10.1007/978-3-7091-7149-3 |
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