Design and Analysis of DNA Microarray Investigations:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2003
|
| Schriftenreihe: | Statistics for Biology and Health
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | This book is targeted to biologists with limited statistical background and to statisticians and computer scientists interested in being effective collaborators on multi-disciplinary DNA microarray projects. State-of-the-art analysis methods are presented with minimal mathematical notation and a focus on concepts. This book is unique because it is authored by statisticians at the National Cancer Institute who are actively involved in the application of microarray technology. Many laboratories are not equipped to effectively design and analyze studies that take advantage of the promise of microarrays. Many of the software packages available to biologists were developed without involvement of statisticians experienced in such studies and contain tools that may not be optimal for particular applications. This book provides a sound preparation for designing microarray studies that have clear objectives, and for selecting analysis tools and strategies that provide clear and valid answers. The book offers an in depth understanding of the design and analysis of experiments utilizing microarrays and should benefit scientists regardless of what software packages they prefer. In order to provide all readers with hands on experience in data analysis, it includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is freely available from the National Cancer Institute for non-commercial use. The authors are current or former members of the Biometric Research Branch at the National Cancer Institute. They have collaborated on major biomedical studies utilizing microarrays and in the development of statistical methodology for the design and analysis of microarray investigations. Dr. Simon, chief of the branch, is also the architect of BRB-ArrayTools |
| Beschreibung: | 1 Online-Ressource (X, 200 p) |
| ISBN: | 9780387218663 9780387001357 |
| ISSN: | 1431-8776 |
| DOI: | 10.1007/b97583 |
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Datensatz im Suchindex
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| any_adam_object | |
| author | Simon, Richard M. 1943- |
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| id | DE-604.BV042419018 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:21:03Z |
| institution | BVB |
| isbn | 9780387218663 9780387001357 |
| issn | 1431-8776 |
| language | English |
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| spelling | Simon, Richard M. 1943- Verfasser (DE-588)128738170 aut Design and Analysis of DNA Microarray Investigations by Richard M. Simon, Edward L. Korn, Lisa M. McShane, Michael D. Radmacher, George W. Wright, Yingdong Zhao New York, NY Springer New York 2003 1 Online-Ressource (X, 200 p) txt rdacontent c rdamedia cr rdacarrier Statistics for Biology and Health 1431-8776 This book is targeted to biologists with limited statistical background and to statisticians and computer scientists interested in being effective collaborators on multi-disciplinary DNA microarray projects. State-of-the-art analysis methods are presented with minimal mathematical notation and a focus on concepts. This book is unique because it is authored by statisticians at the National Cancer Institute who are actively involved in the application of microarray technology. Many laboratories are not equipped to effectively design and analyze studies that take advantage of the promise of microarrays. Many of the software packages available to biologists were developed without involvement of statisticians experienced in such studies and contain tools that may not be optimal for particular applications. This book provides a sound preparation for designing microarray studies that have clear objectives, and for selecting analysis tools and strategies that provide clear and valid answers. The book offers an in depth understanding of the design and analysis of experiments utilizing microarrays and should benefit scientists regardless of what software packages they prefer. In order to provide all readers with hands on experience in data analysis, it includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is freely available from the National Cancer Institute for non-commercial use. The authors are current or former members of the Biometric Research Branch at the National Cancer Institute. They have collaborated on major biomedical studies utilizing microarrays and in the development of statistical methodology for the design and analysis of microarray investigations. Dr. Simon, chief of the branch, is also the architect of BRB-ArrayTools Statistics Oncology Medicine Toxicology Medical records / Data processing Bioinformatics Cancer Research Statistics for Life Sciences, Medicine, Health Sciences Molecular Medicine Pharmacology/Toxicology Health Informatics Datenverarbeitung Medizin Statistik Statistik (DE-588)4056995-0 gnd rswk-swf Microarray (DE-588)4544227-7 gnd rswk-swf DNS (DE-588)4070512-2 gnd rswk-swf DNS (DE-588)4070512-2 s Microarray (DE-588)4544227-7 s Statistik (DE-588)4056995-0 s 1\p DE-604 Korn, Edward Lee 1951- Sonstige (DE-588)173351913 oth McShane, Lisa M. Sonstige oth Radmacher, Michael D. Sonstige oth Wright, George W. Sonstige oth Zhao, Yingdong Sonstige oth https://doi.org/10.1007/b97583 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Simon, Richard M. 1943- Design and Analysis of DNA Microarray Investigations Statistics Oncology Medicine Toxicology Medical records / Data processing Bioinformatics Cancer Research Statistics for Life Sciences, Medicine, Health Sciences Molecular Medicine Pharmacology/Toxicology Health Informatics Datenverarbeitung Medizin Statistik Statistik (DE-588)4056995-0 gnd Microarray (DE-588)4544227-7 gnd DNS (DE-588)4070512-2 gnd |
| subject_GND | (DE-588)4056995-0 (DE-588)4544227-7 (DE-588)4070512-2 |
| title | Design and Analysis of DNA Microarray Investigations |
| title_auth | Design and Analysis of DNA Microarray Investigations |
| title_exact_search | Design and Analysis of DNA Microarray Investigations |
| title_full | Design and Analysis of DNA Microarray Investigations by Richard M. Simon, Edward L. Korn, Lisa M. McShane, Michael D. Radmacher, George W. Wright, Yingdong Zhao |
| title_fullStr | Design and Analysis of DNA Microarray Investigations by Richard M. Simon, Edward L. Korn, Lisa M. McShane, Michael D. Radmacher, George W. Wright, Yingdong Zhao |
| title_full_unstemmed | Design and Analysis of DNA Microarray Investigations by Richard M. Simon, Edward L. Korn, Lisa M. McShane, Michael D. Radmacher, George W. Wright, Yingdong Zhao |
| title_short | Design and Analysis of DNA Microarray Investigations |
| title_sort | design and analysis of dna microarray investigations |
| topic | Statistics Oncology Medicine Toxicology Medical records / Data processing Bioinformatics Cancer Research Statistics for Life Sciences, Medicine, Health Sciences Molecular Medicine Pharmacology/Toxicology Health Informatics Datenverarbeitung Medizin Statistik Statistik (DE-588)4056995-0 gnd Microarray (DE-588)4544227-7 gnd DNS (DE-588)4070512-2 gnd |
| topic_facet | Statistics Oncology Medicine Toxicology Medical records / Data processing Bioinformatics Cancer Research Statistics for Life Sciences, Medicine, Health Sciences Molecular Medicine Pharmacology/Toxicology Health Informatics Datenverarbeitung Medizin Statistik Microarray DNS |
| url | https://doi.org/10.1007/b97583 |
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