Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
1983
|
| Schriftenreihe: | Environmental Science Research
27 |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | In the four years since the 1978 Symposium on the Application of Short-Term Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures the use of short-term bioassays to evaluate potential health hazards of complex environmental mixtures has substantially increased. Increased research activity has been particularly noticeable in mobile source emissions, where initial observations on the mutagenic activity of diesel particulate extracts reported at the 1978 symposium stimulated the development of major research programs in government and industry. In the absence of appropriate reference materials, the U.S. Environmental Protection Agency initiated comparative genotoxicity studies to determine the relative mutagenic and carcinogenic activity and, ultimately, the potential human health risk due to exposure to various complex emission products. Among the materials investigated were those of known health risk, such as coke oven and roofing tar emissions and cigarette smoke condensates, and those of unknown hazard, such as exhaust from diesel-and gasoline-powered vehicles. Studies on diesel emission products proved useful in short term bioassay development, as the diesel exhaust extracts were genetically active with low cellular toxicity and could be obtained in relatively large quantities. Availability of such samples aided chemical characterization, and it was eventually determined that the nitro-polynuclear aromatic hydrocarbons were among the mutagenic components of diesel exhaust particulate |
| Beschreibung: | 1 Online-Ressource (589p) |
| ISBN: | 9781461336112 9781461336136 |
| DOI: | 10.1007/978-1-4613-3611-2 |
Internformat
MARC
| LEADER | 00000nmm a2200000zcb4500 | ||
|---|---|---|---|
| 001 | BV042411428 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 150316s1983 |||| o||u| ||||||eng d | ||
| 020 | |a 9781461336112 |c Online |9 978-1-4613-3611-2 | ||
| 020 | |a 9781461336136 |c Print |9 978-1-4613-3613-6 | ||
| 024 | 7 | |a 10.1007/978-1-4613-3611-2 |2 doi | |
| 035 | |a (OCoLC)863788554 | ||
| 035 | |a (DE-599)BVBBV042411428 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-91 |a DE-83 | ||
| 082 | 0 | |a 530 |2 23 | |
| 084 | |a PHY 000 |2 stub | ||
| 100 | 1 | |a Waters, Michael D. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III |c edited by Michael D. Waters, Shahbeg S. Sandhu, Joellen Lewtas, Larry Claxton, Neil Chernoff, Stephen Nesnow |
| 264 | 1 | |a Boston, MA |b Springer US |c 1983 | |
| 300 | |a 1 Online-Ressource (589p) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Environmental Science Research |v 27 | |
| 500 | |a In the four years since the 1978 Symposium on the Application of Short-Term Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures the use of short-term bioassays to evaluate potential health hazards of complex environmental mixtures has substantially increased. Increased research activity has been particularly noticeable in mobile source emissions, where initial observations on the mutagenic activity of diesel particulate extracts reported at the 1978 symposium stimulated the development of major research programs in government and industry. In the absence of appropriate reference materials, the U.S. Environmental Protection Agency initiated comparative genotoxicity studies to determine the relative mutagenic and carcinogenic activity and, ultimately, the potential human health risk due to exposure to various complex emission products. Among the materials investigated were those of known health risk, such as coke oven and roofing tar emissions and cigarette smoke condensates, and those of unknown hazard, such as exhaust from diesel-and gasoline-powered vehicles. Studies on diesel emission products proved useful in short term bioassay development, as the diesel exhaust extracts were genetically active with low cellular toxicity and could be obtained in relatively large quantities. Availability of such samples aided chemical characterization, and it was eventually determined that the nitro-polynuclear aromatic hydrocarbons were among the mutagenic components of diesel exhaust particulate | ||
| 650 | 4 | |a Physics | |
| 650 | 4 | |a Physics, general | |
| 700 | 1 | |a Sandhu, Shahbeg S. |e Sonstige |4 oth | |
| 700 | 1 | |a Lewtas, Joellen |e Sonstige |4 oth | |
| 700 | 1 | |a Claxton, Larry |e Sonstige |4 oth | |
| 700 | 1 | |a Chernoff, Neil |e Sonstige |4 oth | |
| 700 | 1 | |a Nesnow, Stephen |e Sonstige |4 oth | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-1-4613-3611-2 |x Verlag |3 Volltext |
| 912 | |a ZDB-2-PHA |a ZDB-2-BAE | ||
| 940 | 1 | |q ZDB-2-PHA_Archive | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-027846921 | ||
Datensatz im Suchindex
| _version_ | 1804153072824352768 |
|---|---|
| any_adam_object | |
| author | Waters, Michael D. |
| author_facet | Waters, Michael D. |
| author_role | aut |
| author_sort | Waters, Michael D. |
| author_variant | m d w md mdw |
| building | Verbundindex |
| bvnumber | BV042411428 |
| classification_tum | PHY 000 |
| collection | ZDB-2-PHA ZDB-2-BAE |
| ctrlnum | (OCoLC)863788554 (DE-599)BVBBV042411428 |
| dewey-full | 530 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 530 - Physics |
| dewey-raw | 530 |
| dewey-search | 530 |
| dewey-sort | 3530 |
| dewey-tens | 530 - Physics |
| discipline | Physik |
| doi_str_mv | 10.1007/978-1-4613-3611-2 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03075nmm a2200445zcb4500</leader><controlfield tag="001">BV042411428</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">150316s1983 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781461336112</subfield><subfield code="c">Online</subfield><subfield code="9">978-1-4613-3611-2</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781461336136</subfield><subfield code="c">Print</subfield><subfield code="9">978-1-4613-3613-6</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-4613-3611-2</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)863788554</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV042411428</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-91</subfield><subfield code="a">DE-83</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">530</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">PHY 000</subfield><subfield code="2">stub</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Waters, Michael D.</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III</subfield><subfield code="c">edited by Michael D. Waters, Shahbeg S. Sandhu, Joellen Lewtas, Larry Claxton, Neil Chernoff, Stephen Nesnow</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Boston, MA</subfield><subfield code="b">Springer US</subfield><subfield code="c">1983</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (589p)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Environmental Science Research</subfield><subfield code="v">27</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">In the four years since the 1978 Symposium on the Application of Short-Term Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures the use of short-term bioassays to evaluate potential health hazards of complex environmental mixtures has substantially increased. Increased research activity has been particularly noticeable in mobile source emissions, where initial observations on the mutagenic activity of diesel particulate extracts reported at the 1978 symposium stimulated the development of major research programs in government and industry. In the absence of appropriate reference materials, the U.S. Environmental Protection Agency initiated comparative genotoxicity studies to determine the relative mutagenic and carcinogenic activity and, ultimately, the potential human health risk due to exposure to various complex emission products. Among the materials investigated were those of known health risk, such as coke oven and roofing tar emissions and cigarette smoke condensates, and those of unknown hazard, such as exhaust from diesel-and gasoline-powered vehicles. Studies on diesel emission products proved useful in short term bioassay development, as the diesel exhaust extracts were genetically active with low cellular toxicity and could be obtained in relatively large quantities. Availability of such samples aided chemical characterization, and it was eventually determined that the nitro-polynuclear aromatic hydrocarbons were among the mutagenic components of diesel exhaust particulate</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Physics</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Physics, general</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sandhu, Shahbeg S.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lewtas, Joellen</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Claxton, Larry</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chernoff, Neil</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nesnow, Stephen</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-4613-3611-2</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-PHA</subfield><subfield code="a">ZDB-2-BAE</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">ZDB-2-PHA_Archive</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-027846921</subfield></datafield></record></collection> |
| id | DE-604.BV042411428 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:20:48Z |
| institution | BVB |
| isbn | 9781461336112 9781461336136 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027846921 |
| oclc_num | 863788554 |
| open_access_boolean | |
| owner | DE-91 DE-BY-TUM DE-83 |
| owner_facet | DE-91 DE-BY-TUM DE-83 |
| physical | 1 Online-Ressource (589p) |
| psigel | ZDB-2-PHA ZDB-2-BAE ZDB-2-PHA_Archive |
| publishDate | 1983 |
| publishDateSearch | 1983 |
| publishDateSort | 1983 |
| publisher | Springer US |
| record_format | marc |
| series2 | Environmental Science Research |
| spelling | Waters, Michael D. Verfasser aut Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III edited by Michael D. Waters, Shahbeg S. Sandhu, Joellen Lewtas, Larry Claxton, Neil Chernoff, Stephen Nesnow Boston, MA Springer US 1983 1 Online-Ressource (589p) txt rdacontent c rdamedia cr rdacarrier Environmental Science Research 27 In the four years since the 1978 Symposium on the Application of Short-Term Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures the use of short-term bioassays to evaluate potential health hazards of complex environmental mixtures has substantially increased. Increased research activity has been particularly noticeable in mobile source emissions, where initial observations on the mutagenic activity of diesel particulate extracts reported at the 1978 symposium stimulated the development of major research programs in government and industry. In the absence of appropriate reference materials, the U.S. Environmental Protection Agency initiated comparative genotoxicity studies to determine the relative mutagenic and carcinogenic activity and, ultimately, the potential human health risk due to exposure to various complex emission products. Among the materials investigated were those of known health risk, such as coke oven and roofing tar emissions and cigarette smoke condensates, and those of unknown hazard, such as exhaust from diesel-and gasoline-powered vehicles. Studies on diesel emission products proved useful in short term bioassay development, as the diesel exhaust extracts were genetically active with low cellular toxicity and could be obtained in relatively large quantities. Availability of such samples aided chemical characterization, and it was eventually determined that the nitro-polynuclear aromatic hydrocarbons were among the mutagenic components of diesel exhaust particulate Physics Physics, general Sandhu, Shahbeg S. Sonstige oth Lewtas, Joellen Sonstige oth Claxton, Larry Sonstige oth Chernoff, Neil Sonstige oth Nesnow, Stephen Sonstige oth https://doi.org/10.1007/978-1-4613-3611-2 Verlag Volltext |
| spellingShingle | Waters, Michael D. Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III Physics Physics, general |
| title | Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III |
| title_auth | Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III |
| title_exact_search | Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III |
| title_full | Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III edited by Michael D. Waters, Shahbeg S. Sandhu, Joellen Lewtas, Larry Claxton, Neil Chernoff, Stephen Nesnow |
| title_fullStr | Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III edited by Michael D. Waters, Shahbeg S. Sandhu, Joellen Lewtas, Larry Claxton, Neil Chernoff, Stephen Nesnow |
| title_full_unstemmed | Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III edited by Michael D. Waters, Shahbeg S. Sandhu, Joellen Lewtas, Larry Claxton, Neil Chernoff, Stephen Nesnow |
| title_short | Short-Term Bioassays in the Analysis of Complex Environmental Mixtures III |
| title_sort | short term bioassays in the analysis of complex environmental mixtures iii |
| topic | Physics Physics, general |
| topic_facet | Physics Physics, general |
| url | https://doi.org/10.1007/978-1-4613-3611-2 |
| work_keys_str_mv | AT watersmichaeld shorttermbioassaysintheanalysisofcomplexenvironmentalmixturesiii AT sandhushahbegs shorttermbioassaysintheanalysisofcomplexenvironmentalmixturesiii AT lewtasjoellen shorttermbioassaysintheanalysisofcomplexenvironmentalmixturesiii AT claxtonlarry shorttermbioassaysintheanalysisofcomplexenvironmentalmixturesiii AT chernoffneil shorttermbioassaysintheanalysisofcomplexenvironmentalmixturesiii AT nesnowstephen shorttermbioassaysintheanalysisofcomplexenvironmentalmixturesiii |