Molecular Biophysics of the Extracellular Matrix:
Gespeichert in:
Weitere Verfasser: | , , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Totowa, NJ
Humana Press
1984
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Schlagworte: | |
Online-Zugang: | Volltext |
Beschreibung: | Biopolymers, such as proteins and nucleic acids have been subjected to a rational succession of structural studies in which the determination of chemical compositions, linkages, and sequences is followed by investigations of molecular architecture and interactions. By the end of the 1960s the covalent structures of glycosaminoglycans and proteoglycans had been defined both within the carbohydrate chains and in respect to their linkages to protein. The scene was therefore set for successful probing of threedimensional shapes and intermolecular associations. Fortunately, during the 1970s appropriate physical methods were themselves greatly increasing in power. Consequently much progress has been made using X-ray diffraction analysis of hydrated films, nuclear magnetic resonance spectroscopy, and chromatographie methods for investigation of molecular interactions in solution. We now have a great deal of information about molecular shapes, their sensitivity to environment (especially associated cations), and their modes of interaction that could be relevant to supermolecular assemblies in biological milieux. For these reasons we judged that it would be timely to distil the main conclusions from this phase of research to prepare for the next, which will involve detailed study of the interplay between biological function and molecular structure. The idea for this volume emerged from a workshop meeting at Colworth sponsored by the Biochemical Society |
Beschreibung: | 1 Online-Ressource (189p) |
ISBN: | 9781461251668 9781461295938 |
DOI: | 10.1007/978-1-4612-5166-8 |
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spelling | Molecular Biophysics of the Extracellular Matrix edited by Struther Arnott, D. A. Rees, E. R. Morris Totowa, NJ Humana Press 1984 1 Online-Ressource (189p) txt rdacontent c rdamedia cr rdacarrier Biopolymers, such as proteins and nucleic acids have been subjected to a rational succession of structural studies in which the determination of chemical compositions, linkages, and sequences is followed by investigations of molecular architecture and interactions. By the end of the 1960s the covalent structures of glycosaminoglycans and proteoglycans had been defined both within the carbohydrate chains and in respect to their linkages to protein. The scene was therefore set for successful probing of threedimensional shapes and intermolecular associations. Fortunately, during the 1970s appropriate physical methods were themselves greatly increasing in power. Consequently much progress has been made using X-ray diffraction analysis of hydrated films, nuclear magnetic resonance spectroscopy, and chromatographie methods for investigation of molecular interactions in solution. We now have a great deal of information about molecular shapes, their sensitivity to environment (especially associated cations), and their modes of interaction that could be relevant to supermolecular assemblies in biological milieux. For these reasons we judged that it would be timely to distil the main conclusions from this phase of research to prepare for the next, which will involve detailed study of the interplay between biological function and molecular structure. The idea for this volume emerged from a workshop meeting at Colworth sponsored by the Biochemical Society Physics Biochemistry Cytology Biophysics and Biological Physics Biochemistry, general Cell Biology Grundsubstanz (DE-588)4224942-9 gnd rswk-swf Proteoglykane (DE-588)4176001-3 gnd rswk-swf Physikalische Chemie (DE-588)4045959-7 gnd rswk-swf Proteoglykane (DE-588)4176001-3 s Grundsubstanz (DE-588)4224942-9 s Physikalische Chemie (DE-588)4045959-7 s 1\p DE-604 Arnott, Struther edt Rees, D. A. edt Morris, E. R. edt https://doi.org/10.1007/978-1-4612-5166-8 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Molecular Biophysics of the Extracellular Matrix Physics Biochemistry Cytology Biophysics and Biological Physics Biochemistry, general Cell Biology Grundsubstanz (DE-588)4224942-9 gnd Proteoglykane (DE-588)4176001-3 gnd Physikalische Chemie (DE-588)4045959-7 gnd |
subject_GND | (DE-588)4224942-9 (DE-588)4176001-3 (DE-588)4045959-7 |
title | Molecular Biophysics of the Extracellular Matrix |
title_auth | Molecular Biophysics of the Extracellular Matrix |
title_exact_search | Molecular Biophysics of the Extracellular Matrix |
title_full | Molecular Biophysics of the Extracellular Matrix edited by Struther Arnott, D. A. Rees, E. R. Morris |
title_fullStr | Molecular Biophysics of the Extracellular Matrix edited by Struther Arnott, D. A. Rees, E. R. Morris |
title_full_unstemmed | Molecular Biophysics of the Extracellular Matrix edited by Struther Arnott, D. A. Rees, E. R. Morris |
title_short | Molecular Biophysics of the Extracellular Matrix |
title_sort | molecular biophysics of the extracellular matrix |
topic | Physics Biochemistry Cytology Biophysics and Biological Physics Biochemistry, general Cell Biology Grundsubstanz (DE-588)4224942-9 gnd Proteoglykane (DE-588)4176001-3 gnd Physikalische Chemie (DE-588)4045959-7 gnd |
topic_facet | Physics Biochemistry Cytology Biophysics and Biological Physics Biochemistry, general Cell Biology Grundsubstanz Proteoglykane Physikalische Chemie |
url | https://doi.org/10.1007/978-1-4612-5166-8 |
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