Brainstorming: The Science and Politics of Opiate Research
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, Mass.
Harvard University Press
[1989]
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| Schlagworte: | |
| Online-Zugang: | FAB01 FAW01 FCO01 FHA01 FKE01 FLA01 UPA01 Volltext |
| Beschreibung: | 11 schw.-w. Abb In this book Solomon Snyder describes the political maneuverings and scientific sleuthing that led him and Candace Pert, then a graduate student in his lab, to a critical breakthrough in the effort to understand addiction. Their discovery--the so-called opiate receptor--is a structure on the surface of certain nerve cells that attracts opiates. From this very human chronicle of scientific battles in the ongoing war against pain and addiction, we gain an appreciation of the extraordinary intellectual processes of an eminent scientist. But Dr. Snyder's story of scientific brainstorming also affords us rare glimpses into the fruitful, sometimes frustrating, relationships among scientists which enrich and complicate creative work The discovery of how opiates such as morphine and heroin relieve pain and produce euphoria is one of the most dramatic tales of modern science. It begins in 1971 when, at the height of the undeclared war in Vietnam, Richard Nixon officially announced a war on drugs. Heroin addiction--no longer confined to urban ghettos--was causing bad public relations for the White House. The specter of young American soldiers demoralized, drugged, and committing atrocities was not the image President Nixon wished to convey as he argued for further bombings of North Vietnam. In this book Solomon Snyder describes the political maneuverings and scientific sleuthing that led him and Candace Pert, then a graduate student in his lab, to a critical breakthrough in the effort to understand addiction. Their discovery--the so-called opiate receptor--is a structure on the surface of certain nerve cells that attracts opiates. Heroin or morphine molecules fit into opiate receptors much as a key fits into the ignition switch of a car--thus turning on the engine of the cell. Snyder and his students were able to show that nerve cells which possess opiate receptors are found in precisely those parts of the brain that control emotion and pain. Dr. Snyder describes the friendly yet intense competition from other researchers to expand upon this initial discovery. From the work of two Scottish investigators, Hans Kosterlitz and John Hughes, neuroscientists now know not only where opiate receptors are found in the brain but also why they are there: to serve as binding sites for an opiate-like substance produced by the brain itself--the brain's own morphine. This substance, called enkephalin, regulates pain, mood, and a host of other physiological functions. From this very human chronicle of scientific battles in the ongoing war against pain and addiction, we gain an appreciation of the extraordinary intellectual processes of an eminent scientist. But Dr. Snyder's story of scientific brainstorming also affords us rare glimpses into the fruitful, sometimes frustrating, relationships among scientists which enrich and complicate creative work. We are reminded of the delicate political alliances that are forged at every level of organization, from the lab bench to the Oval Office, as the scientific community attempts to fit its needs to those of the larger society |
| Beschreibung: | 1 Online-Ressource (208p.) |
| ISBN: | 9780674366015 |
| DOI: | 10.4159/harvard.9780674366015 |
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| 500 | |a In this book Solomon Snyder describes the political maneuverings and scientific sleuthing that led him and Candace Pert, then a graduate student in his lab, to a critical breakthrough in the effort to understand addiction. Their discovery--the so-called opiate receptor--is a structure on the surface of certain nerve cells that attracts opiates. From this very human chronicle of scientific battles in the ongoing war against pain and addiction, we gain an appreciation of the extraordinary intellectual processes of an eminent scientist. But Dr. Snyder's story of scientific brainstorming also affords us rare glimpses into the fruitful, sometimes frustrating, relationships among scientists which enrich and complicate creative work | ||
| 500 | |a The discovery of how opiates such as morphine and heroin relieve pain and produce euphoria is one of the most dramatic tales of modern science. It begins in 1971 when, at the height of the undeclared war in Vietnam, Richard Nixon officially announced a war on drugs. Heroin addiction--no longer confined to urban ghettos--was causing bad public relations for the White House. The specter of young American soldiers demoralized, drugged, and committing atrocities was not the image President Nixon wished to convey as he argued for further bombings of North Vietnam. In this book Solomon Snyder describes the political maneuverings and scientific sleuthing that led him and Candace Pert, then a graduate student in his lab, to a critical breakthrough in the effort to understand addiction. Their discovery--the so-called opiate receptor--is a structure on the surface of certain nerve cells that attracts opiates. | ||
| 500 | |a Heroin or morphine molecules fit into opiate receptors much as a key fits into the ignition switch of a car--thus turning on the engine of the cell. Snyder and his students were able to show that nerve cells which possess opiate receptors are found in precisely those parts of the brain that control emotion and pain. Dr. Snyder describes the friendly yet intense competition from other researchers to expand upon this initial discovery. From the work of two Scottish investigators, Hans Kosterlitz and John Hughes, neuroscientists now know not only where opiate receptors are found in the brain but also why they are there: to serve as binding sites for an opiate-like substance produced by the brain itself--the brain's own morphine. This substance, called enkephalin, regulates pain, mood, and a host of other physiological functions. | ||
| 500 | |a From this very human chronicle of scientific battles in the ongoing war against pain and addiction, we gain an appreciation of the extraordinary intellectual processes of an eminent scientist. But Dr. Snyder's story of scientific brainstorming also affords us rare glimpses into the fruitful, sometimes frustrating, relationships among scientists which enrich and complicate creative work. We are reminded of the delicate political alliances that are forged at every level of organization, from the lab bench to the Oval Office, as the scientific community attempts to fit its needs to those of the larger society | ||
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Datensatz im Suchindex
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| any_adam_object | |
| author | Snyder, Solomon H. |
| author_facet | Snyder, Solomon H. |
| author_role | aut |
| author_sort | Snyder, Solomon H. |
| author_variant | s h s sh shs |
| building | Verbundindex |
| bvnumber | BV042344103 |
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| ctrlnum | (OCoLC)1013963338 (DE-599)BVBBV042344103 |
| dewey-full | 612.8/22 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.8/22 |
| dewey-search | 612.8/22 |
| dewey-sort | 3612.8 222 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.4159/harvard.9780674366015 |
| format | Electronic eBook |
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| genre_facet | Erlebnisbericht |
| geographic | USA USA (DE-588)4078704-7 gnd |
| geographic_facet | USA |
| id | DE-604.BV042344103 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:18:58Z |
| institution | BVB |
| isbn | 9780674366015 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027780584 |
| oclc_num | 1013963338 |
| open_access_boolean | |
| owner | DE-859 DE-860 DE-Aug4 DE-739 DE-1046 DE-1043 DE-858 |
| owner_facet | DE-859 DE-860 DE-Aug4 DE-739 DE-1046 DE-1043 DE-858 |
| physical | 1 Online-Ressource (208p.) |
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| publishDate | 1989 |
| publishDateSearch | 1989 |
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| publisher | Harvard University Press |
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| spelling | Snyder, Solomon H. Verfasser aut Brainstorming The Science and Politics of Opiate Research Solomon H. Snyder Cambridge, Mass. Harvard University Press [1989] 1 Online-Ressource (208p.) txt rdacontent c rdamedia cr rdacarrier 11 schw.-w. Abb In this book Solomon Snyder describes the political maneuverings and scientific sleuthing that led him and Candace Pert, then a graduate student in his lab, to a critical breakthrough in the effort to understand addiction. Their discovery--the so-called opiate receptor--is a structure on the surface of certain nerve cells that attracts opiates. From this very human chronicle of scientific battles in the ongoing war against pain and addiction, we gain an appreciation of the extraordinary intellectual processes of an eminent scientist. But Dr. Snyder's story of scientific brainstorming also affords us rare glimpses into the fruitful, sometimes frustrating, relationships among scientists which enrich and complicate creative work The discovery of how opiates such as morphine and heroin relieve pain and produce euphoria is one of the most dramatic tales of modern science. It begins in 1971 when, at the height of the undeclared war in Vietnam, Richard Nixon officially announced a war on drugs. Heroin addiction--no longer confined to urban ghettos--was causing bad public relations for the White House. The specter of young American soldiers demoralized, drugged, and committing atrocities was not the image President Nixon wished to convey as he argued for further bombings of North Vietnam. In this book Solomon Snyder describes the political maneuverings and scientific sleuthing that led him and Candace Pert, then a graduate student in his lab, to a critical breakthrough in the effort to understand addiction. Their discovery--the so-called opiate receptor--is a structure on the surface of certain nerve cells that attracts opiates. Heroin or morphine molecules fit into opiate receptors much as a key fits into the ignition switch of a car--thus turning on the engine of the cell. Snyder and his students were able to show that nerve cells which possess opiate receptors are found in precisely those parts of the brain that control emotion and pain. Dr. Snyder describes the friendly yet intense competition from other researchers to expand upon this initial discovery. From the work of two Scottish investigators, Hans Kosterlitz and John Hughes, neuroscientists now know not only where opiate receptors are found in the brain but also why they are there: to serve as binding sites for an opiate-like substance produced by the brain itself--the brain's own morphine. This substance, called enkephalin, regulates pain, mood, and a host of other physiological functions. From this very human chronicle of scientific battles in the ongoing war against pain and addiction, we gain an appreciation of the extraordinary intellectual processes of an eminent scientist. But Dr. Snyder's story of scientific brainstorming also affords us rare glimpses into the fruitful, sometimes frustrating, relationships among scientists which enrich and complicate creative work. We are reminded of the delicate political alliances that are forged at every level of organization, from the lab bench to the Oval Office, as the scientific community attempts to fit its needs to those of the larger society In English Endorphins / Receptors / Research Endorphins / Receptors / Research / Political aspects / United States Endorphins / United States / History Politics / United States Receptors, Opioid / United States / History Research / United States / History Substance-Related Disorders / United States / History Endorfina (aspectos políticos;pesquisa;história) / Estados unidos Ópio (aspectos políticos;pesquisa;história) / Estados unidos Geschichte Politik Medizin, Gesundheit Endorfinen Receptoren Opiaten Onderzoek Receptores Neuropeptídeos Neuroquímica Opiatrezeptor Forschung Erlebnisbericht Opiate Hirnstoffwechsel Forschungspolitik Hirnstoffwechsel (DE-588)4195457-9 gnd rswk-swf Opiate (DE-588)4075669-5 gnd rswk-swf Forschung (DE-588)4017894-8 gnd rswk-swf Opiatrezeptor (DE-588)4172636-4 gnd rswk-swf Forschungspolitik (DE-588)4125050-3 gnd rswk-swf USA USA (DE-588)4078704-7 gnd rswk-swf 1\p (DE-588)4133254-4 Erlebnisbericht gnd-content USA (DE-588)4078704-7 g Opiate (DE-588)4075669-5 s Hirnstoffwechsel (DE-588)4195457-9 s Forschungspolitik (DE-588)4125050-3 s 2\p DE-604 Opiatrezeptor (DE-588)4172636-4 s Forschung (DE-588)4017894-8 s 3\p DE-604 Erscheint auch als Druckausgabe 978-0-674-36600-8 https://doi.org/10.4159/harvard.9780674366015 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Snyder, Solomon H. Brainstorming The Science and Politics of Opiate Research Endorphins / Receptors / Research Endorphins / Receptors / Research / Political aspects / United States Endorphins / United States / History Politics / United States Receptors, Opioid / United States / History Research / United States / History Substance-Related Disorders / United States / History Endorfina (aspectos políticos;pesquisa;história) / Estados unidos Ópio (aspectos políticos;pesquisa;história) / Estados unidos Geschichte Politik Medizin, Gesundheit Endorfinen Receptoren Opiaten Onderzoek Receptores Neuropeptídeos Neuroquímica Opiatrezeptor Forschung Erlebnisbericht Opiate Hirnstoffwechsel Forschungspolitik Hirnstoffwechsel (DE-588)4195457-9 gnd Opiate (DE-588)4075669-5 gnd Forschung (DE-588)4017894-8 gnd Opiatrezeptor (DE-588)4172636-4 gnd Forschungspolitik (DE-588)4125050-3 gnd |
| subject_GND | (DE-588)4195457-9 (DE-588)4075669-5 (DE-588)4017894-8 (DE-588)4172636-4 (DE-588)4125050-3 (DE-588)4078704-7 (DE-588)4133254-4 |
| title | Brainstorming The Science and Politics of Opiate Research |
| title_auth | Brainstorming The Science and Politics of Opiate Research |
| title_exact_search | Brainstorming The Science and Politics of Opiate Research |
| title_full | Brainstorming The Science and Politics of Opiate Research Solomon H. Snyder |
| title_fullStr | Brainstorming The Science and Politics of Opiate Research Solomon H. Snyder |
| title_full_unstemmed | Brainstorming The Science and Politics of Opiate Research Solomon H. Snyder |
| title_short | Brainstorming |
| title_sort | brainstorming the science and politics of opiate research |
| title_sub | The Science and Politics of Opiate Research |
| topic | Endorphins / Receptors / Research Endorphins / Receptors / Research / Political aspects / United States Endorphins / United States / History Politics / United States Receptors, Opioid / United States / History Research / United States / History Substance-Related Disorders / United States / History Endorfina (aspectos políticos;pesquisa;história) / Estados unidos Ópio (aspectos políticos;pesquisa;história) / Estados unidos Geschichte Politik Medizin, Gesundheit Endorfinen Receptoren Opiaten Onderzoek Receptores Neuropeptídeos Neuroquímica Opiatrezeptor Forschung Erlebnisbericht Opiate Hirnstoffwechsel Forschungspolitik Hirnstoffwechsel (DE-588)4195457-9 gnd Opiate (DE-588)4075669-5 gnd Forschung (DE-588)4017894-8 gnd Opiatrezeptor (DE-588)4172636-4 gnd Forschungspolitik (DE-588)4125050-3 gnd |
| topic_facet | Endorphins / Receptors / Research Endorphins / Receptors / Research / Political aspects / United States Endorphins / United States / History Politics / United States Receptors, Opioid / United States / History Research / United States / History Substance-Related Disorders / United States / History Endorfina (aspectos políticos;pesquisa;história) / Estados unidos Ópio (aspectos políticos;pesquisa;história) / Estados unidos Geschichte Politik Medizin, Gesundheit Endorfinen Receptoren Opiaten Onderzoek Receptores Neuropeptídeos Neuroquímica Opiatrezeptor Forschung Erlebnisbericht Opiate Hirnstoffwechsel Forschungspolitik USA |
| url | https://doi.org/10.4159/harvard.9780674366015 |
| work_keys_str_mv | AT snydersolomonh brainstormingthescienceandpoliticsofopiateresearch |