Molecular and quantitative animal genetics:
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | German |
| Veröffentlicht: |
Hoboken
Wiley
2015
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIII, 313 S. graph. Darst. |
| ISBN: | 9781118677407 |
Internformat
MARC
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Datensatz im Suchindex
| _version_ | 1804152940242403328 |
|---|---|
| adam_text | Molecular and
Quantitative Animal
Genetics
EDITED BY
Hasan Khatib
University of Wisconsin-Madison
Madison, YVJ, USA
WILEY Biackweii
Contents
Contributors, ix
Manuscript reviewers, xi
Preface, xiii
1 Decoding and Encoding the DNA of Teaching
and Learning in College Classrooms, 1
Michel A Wattiaux
Introduction, l
Teaching and learning: definitions, l
Understanding learning, 2
Understanding teaching, 5
Implications for classroom design in the twenty-first
century, 6
Final thoughts, 9
References, 10
Review questions, I I
Section 1: Quantitative and Population Genetics, 13
2 Mating Systems: Inbreeding and
Inbreeding Depression, 15
David L Thomas
Introduction, l 5
Inbreeding, 15
Cause of inbreeding depression, 18
Quantifying inbreeding, 20
Genomics and inbreeding, 23
Summary, 23
Further reading, 24
References, 24
Review questions, 24
3 Genomic Selection, Inbreeding, and
Crossbreeding in Dairy Cattle, 25
Kent Weigel
Introduction, 25
Genomic selection, 25
Crossbreeding, 28
Inbreeding and genetic defects, 29
Summary, 30
Refeiences, 30
Review questions, 3 1
4 Basic Genetic Model for Quantitative Traits, 33
Guilherme J M Rosa
Introduction, 33
Quantitative traits, 33
Expected value and variance: the normal distribution, 33
Basic genetic model for quantitative traits, 35
Heritability and selection, 35
Predicting rate of genetic change from selection, 36
Further rending, 37
References, 37
5 Heritability and Repeatability, 39
Guilherme J M Rosa
Introduction, 39
Heritability, 39
Estimation of heritability and variance components, 40
Prediction of breeding values and of response to selection, 41
Repeatability, 41
References, 42
6 Applications of Statistics in Quantitative
Traits, 43
Hayrettin Okul
Population and sample, 43
Descriptive statistics, 43
Graphically examining the distribution of the data, 47
Normal distribution, 49
Exploring relationships between variables, 53
Summary, 59
Appendix 6 1, 62
Further reading, 62
References 62
Review questions, 63
Section 2: Applications of Genetics and Genomics to
Livestock and Companion Animal Species, 65
7 Genetic Improvement of Beef Cattle, 67
Michael D MacNeil
Introduction, 67
Single trail selection, 67
Contents
National cattle evaluation, 69
Multiple trait selection, 71
Summary, 71
Further reading, 71
References, 72
8 Genetic Improvement in
Sheep through Selection, 73
David L Thomas ^
Products from sheep, 73
Selection among breeds, 73
Selection within a breed or population and the Key
Equation, 73
Adjustment for environmental effects, 73
Phenotypic selection, 75
Estimated breeding values (EBV), 75
Using multiple sources of information, 76
Genetic correlations, 76
Selection intensity, 78
Generation interval (L), 79
Predicting progress from selection, 79
National genetic improvement programs, 80
Summary, 81
Further reading, 82
References, 82
Review questions, 82
9 Genetic Improvement Programs for
Dairy Cattle, 85
Kent Weigel
Introduction, 85
Data collection infrastructure, 85
Estimation of breeding values, 87
Selection for increased productivity, 89
Selection for functional traits, 91
Sire selection, 94
Summary, 94
Further reading, 95
References, 95
Review questions, 96
10 Genetic and Genomic Improvement of Pigs, 97
Max F Rothschild
Introduction, 97
Domestication of swine and breed development, 97
Methods of selection and mating systems, 98
Traits of economic importance, 99
Development of molecular genetic approaches, 100
QTL, candidate genes, and genetic improvement, 100
Sequencing the pig genome, 101
Genomic selection, 102
Databases, 103
Cloning, transgenics, and breeding pigs as biological
models, 103
Future applications to genetic improvement, 103
Acknowledgments, 104
Further reading, 104
References, 104
Review questions, 105
11 Equine Genetics, 107
Jennifer Minick Bormanrt
Color, 107
Genetic defects, 110
Inbreeding and relationship, 113
Selection and improvement, 114
New technologies, 116
Further reading, 117
References, 119
Review questions, 119
12 Genetics and Genomics of the Domestic Dog, 121
Leigh Anne Clark and Alison Starr-Moss
Introduction to canine research, 121
The dog genome, 122
Uncovering the genetic basis of phenotypes, 125
Future challenges, 127
Summary, 128
Further reading, 129
References, 130
Review questions, 130
13 The Sheep Genome, 131
Noelle E Cockett and Chunhua Wu
Investment in sheep genome research, 131
Overview of the sheep genome, 13 1
Genomic resources in sheep, 131
Application of genomic resources, I 34
Summary, 134
References, 135
Review questions, 136
14 Goat Genetics and Genomic Progress, 137
Mulumebet Worku
Introduction, 137
Genetics and goat domestication, 137
Taxonomy, 138
Goat chromosome number and structure, 138
Patterns of inheritance, 139
Quantitative trail loci (QTL), 139
Progress in goat genomics, 139
Biotechnologies and goat genetics, 140
Summary, 140
Further reading, 140
Review questions, 141
Section 3: Molecular Genetics of Production and
Economically Important Traits, 143
15 Bioinformatics in Animal Genetics, 145
Jose A Carrillo and Jiuzhou Song
Introduction, 14 5
Bioinformatics and animal genetics, 145
The importance of bioinformatics in genomics research, 146
Gene expression, 148
Gene regulation, 1 50
Contents
Transcriptomics, 242
Proteomics, 248
Systems biology, 251
Conclusion, 253
Further reading, 253
References, 253
24 The Genetics of In Vitro Produced Embryos, 257
Ashley Driver V
In vitro production: from livestock to humans, 257
Unlocking developmentally important genes in the
pre-implantation embryo, 258
1VP: potential source of genetic alteration?, 259
PGD: genetic screening and human embryos, 259
Screening the embryo: to infinity and beyond?, 260
Embryogenetics: what s next?, 260
Summary, 260
Key terms, 260
References, 261
Review questions, 262
Supplementary videos, 262
Section 5: Genetics of Animal Health
and Biotechnology, 263
25 Understanding the Major Histocompatibility
Complex and Immunoglobulin Genes, 265
Michael G Gonda
Introduction, 265
Overview of the immune system, 265
The major histocompatibility complex loci, 267
Immunoglobulin loci, 268
Summary, 272
Key terms, 273
Further reading and references, 274
Review questions, 274
26 Livestock and Companion Animal Genetics:
Genetics of Infectious Disease
Susceptibility, 275
Michael G Gonda
Introduction, 275
Why is studying the genetics of disease susceptibility
important?, 275
Present applications of genetic selection tools for predicting
disease susceptibility, 276
Current research into genetic selection for
livestock health, 279
Challenges faced when studying the genetics of disease
resistance in livestock, 280
Should we select for increased disease resistance?, 281
Summary, 281
Key terms, 281
Further reading, 282
Review questions, 282
27 Animal Genetics and Welfare, 283
Amin A Fad! and Mark E Cook
Introduction, 283
A continued need for genetic improvements and
knowledge, 283
Welfare, 284
Genetic advancement and animal welfare, 284
Genetic selection that adversely affects fanned animal
welfare, 286
Summary, 287
References, 287
Review questions, 288
28 Animal Biotechnology: Scientific, Regulatory
and Public Acceptance Issues Associated
with Cloned and Genetically Engineered
Animals, 289
Alison L Van F mennaam
What is animal biotechnology?, 289
Cloning, 290
Genetic engineering, 293
Ethical, moral, and animal welfare concerns, 297
Summary, 299
Further reading, 300
References, 300
Review questions, 301
29 Intellectual Property Rights and Animal Genetic
Resources, 303
Jennifer Long and Max F Rothschild
Introduction, 303
Old M/cDonald s Farm meets Dolly
(and her lawyer), 303
What is intellectual property?, 303
Forms of intellectual property, 303
Here a patent, there (not) a patent, 304
Forms of payment or remuneration, 305
Case studies, 306
E-I-E-I-O: The alphabet soup of domestic and international
issues, 307
Public sector research and IP - domestic and international,
Access to animal genetic resources, 307
Summary, 308
Further reading, 308
References, 308
Review questions, 309
Index, 3 1 1
VII I
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| isbn | 9781118677407 |
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| spelling | Molecular and quantitative animal genetics Hasan Khatib Hoboken Wiley 2015 XIII, 313 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier genomics cabt molecular genetics cabt Khatib, Hasan edt HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027770357&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
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| title_fullStr | Molecular and quantitative animal genetics Hasan Khatib |
| title_full_unstemmed | Molecular and quantitative animal genetics Hasan Khatib |
| title_short | Molecular and quantitative animal genetics |
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| topic | genomics cabt molecular genetics cabt |
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