Oxidative stress and neurodegenerative disorders:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Elsevier
2007
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders. * Contains the latest information on the subject of neurodegenerative disorders * Reflects on various factors involved in degeneration and gives suggestions for how to tackle these problems Includes bibliographical references and index |
| Beschreibung: | 1 Online-Ressource (xxii, 772 p.) |
| ISBN: | 9780444528094 0444528091 9780080489490 0080489494 |
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| id | DE-604.BV042310972 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:18:03Z |
| institution | BVB |
| isbn | 9780444528094 0444528091 9780080489490 0080489494 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027747964 |
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| physical | 1 Online-Ressource (xxii, 772 p.) |
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| spelling | Oxidative stress and neurodegenerative disorders editors, G. Ali Qureshi and S. Hasan Parvez Amsterdam Elsevier 2007 1 Online-Ressource (xxii, 772 p.) txt rdacontent c rdamedia cr rdacarrier Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders. * Contains the latest information on the subject of neurodegenerative disorders * Reflects on various factors involved in degeneration and gives suggestions for how to tackle these problems Includes bibliographical references and index HEALTH & FITNESS / Diseases / Nervous System (incl. Brain) bisacsh MEDICAL / Neurology bisacsh Zenuwstelselaandoeningen gtt Oxidatieve stress gtt Nervous system / Degeneration / Pathophysiology fast Neurotoxicology fast Oxidative stress fast Medizin Oxidative stress Nervous system Degeneration Pathophysiology Neurotoxicology Qureshi, G. A. Sonstige oth Parvez, H. Sonstige oth http://www.sciencedirect.com/science/book/9780444528094 Verlag Volltext |
| spellingShingle | Oxidative stress and neurodegenerative disorders HEALTH & FITNESS / Diseases / Nervous System (incl. Brain) bisacsh MEDICAL / Neurology bisacsh Zenuwstelselaandoeningen gtt Oxidatieve stress gtt Nervous system / Degeneration / Pathophysiology fast Neurotoxicology fast Oxidative stress fast Medizin Oxidative stress Nervous system Degeneration Pathophysiology Neurotoxicology |
| title | Oxidative stress and neurodegenerative disorders |
| title_auth | Oxidative stress and neurodegenerative disorders |
| title_exact_search | Oxidative stress and neurodegenerative disorders |
| title_full | Oxidative stress and neurodegenerative disorders editors, G. Ali Qureshi and S. Hasan Parvez |
| title_fullStr | Oxidative stress and neurodegenerative disorders editors, G. Ali Qureshi and S. Hasan Parvez |
| title_full_unstemmed | Oxidative stress and neurodegenerative disorders editors, G. Ali Qureshi and S. Hasan Parvez |
| title_short | Oxidative stress and neurodegenerative disorders |
| title_sort | oxidative stress and neurodegenerative disorders |
| topic | HEALTH & FITNESS / Diseases / Nervous System (incl. Brain) bisacsh MEDICAL / Neurology bisacsh Zenuwstelselaandoeningen gtt Oxidatieve stress gtt Nervous system / Degeneration / Pathophysiology fast Neurotoxicology fast Oxidative stress fast Medizin Oxidative stress Nervous system Degeneration Pathophysiology Neurotoxicology |
| topic_facet | HEALTH & FITNESS / Diseases / Nervous System (incl. Brain) MEDICAL / Neurology Zenuwstelselaandoeningen Oxidatieve stress Nervous system / Degeneration / Pathophysiology Neurotoxicology Oxidative stress Medizin Nervous system Degeneration Pathophysiology |
| url | http://www.sciencedirect.com/science/book/9780444528094 |
| work_keys_str_mv | AT qureshiga oxidativestressandneurodegenerativedisorders AT parvezh oxidativestressandneurodegenerativedisorders |