Appetite and body weight: integrative systems and the development of anti-obesity drugs
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Elsevier Academic Press
c2007
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | There is now enough basic work to sketch out the principal systems at all levels of the brain, from prefrontal cortex to lower brainstem, which are orchestrated to provide control of food selection, preference and consumption. At the same time, the complex interplay between central systems and signals generated from peripheral systems include the gut, liver and fat stores, as well as the interactions with the neuroendocrine system can be described in some detail. A continuing theme throughout the book is that the functional analysis of appetite and food intake cannot be limited to a single focus, e.g. hypothalamic neuropeptides and their interactions, but must be based on a fully integrated view of the several contributing systems. Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs provides an expert guide to the neural, neurochemical, autonomic and endocrine interrelations which underpin appetite and the controls of food intake and body weight. The book covers many of the neurochemical entities that are currently under investigation, including: neuropeptides, leptin, insulin, monoamines and endogenous cannabinoids in relation to appetite and body-weight control. In addition to the neuroscience analysis, there are also chapters that provide an expert guide to some of the key psychological concepts that the researchers believe are essential in trying to understand the phenomena under investigation. The volume will also serve as an authoritative guide to the current emphasis on the development of novel, efficacious anti-obesity medication. * Provides an integrative view of the many systems involved in appetite and how they interact to effect food intake (i.e. the brain, endocrine, gut, liver etc.) * Considers psychological aspects such as incentive, preference, liking and palatability, and sets these concepts in their behavioural, pharmacological and neural contexts * Examines the development of novel anti-obesity drugs, drawing on experience of pharmacological development work, pre-clinical tests for anti-obesity efficacy, and clinical trials of candidate anti-obesity compounds Includes bibliographical references and index |
| Beschreibung: | 1 Online-Ressource (x, 371 p.) |
| ISBN: | 9780123706331 0123706335 9780080466460 008046646X |
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| 500 | |a Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs provides an expert guide to the neural, neurochemical, autonomic and endocrine interrelations which underpin appetite and the controls of food intake and body weight. The book covers many of the neurochemical entities that are currently under investigation, including: neuropeptides, leptin, insulin, monoamines and endogenous cannabinoids in relation to appetite and body-weight control. In addition to the neuroscience analysis, there are also chapters that provide an expert guide to some of the key psychological concepts that the researchers believe are essential in trying to understand the phenomena under investigation. The volume will also serve as an authoritative guide to the current emphasis on the development of novel, efficacious anti-obesity medication. * Provides an integrative view of the many systems involved in appetite and how they interact to effect food intake (i.e. | ||
| 500 | |a the brain, endocrine, gut, liver etc.) * Considers psychological aspects such as incentive, preference, liking and palatability, and sets these concepts in their behavioural, pharmacological and neural contexts * Examines the development of novel anti-obesity drugs, drawing on experience of pharmacological development work, pre-clinical tests for anti-obesity efficacy, and clinical trials of candidate anti-obesity compounds | ||
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| 650 | 7 | |a Body weight |2 fast | |
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| spelling | Appetite and body weight integrative systems and the development of anti-obesity drugs edited by Tim C. Kirkham and Steven J. Cooper Amsterdam Elsevier Academic Press c2007 1 Online-Ressource (x, 371 p.) txt rdacontent c rdamedia cr rdacarrier There is now enough basic work to sketch out the principal systems at all levels of the brain, from prefrontal cortex to lower brainstem, which are orchestrated to provide control of food selection, preference and consumption. At the same time, the complex interplay between central systems and signals generated from peripheral systems include the gut, liver and fat stores, as well as the interactions with the neuroendocrine system can be described in some detail. A continuing theme throughout the book is that the functional analysis of appetite and food intake cannot be limited to a single focus, e.g. hypothalamic neuropeptides and their interactions, but must be based on a fully integrated view of the several contributing systems. Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs provides an expert guide to the neural, neurochemical, autonomic and endocrine interrelations which underpin appetite and the controls of food intake and body weight. The book covers many of the neurochemical entities that are currently under investigation, including: neuropeptides, leptin, insulin, monoamines and endogenous cannabinoids in relation to appetite and body-weight control. In addition to the neuroscience analysis, there are also chapters that provide an expert guide to some of the key psychological concepts that the researchers believe are essential in trying to understand the phenomena under investigation. The volume will also serve as an authoritative guide to the current emphasis on the development of novel, efficacious anti-obesity medication. * Provides an integrative view of the many systems involved in appetite and how they interact to effect food intake (i.e. the brain, endocrine, gut, liver etc.) * Considers psychological aspects such as incentive, preference, liking and palatability, and sets these concepts in their behavioural, pharmacological and neural contexts * Examines the development of novel anti-obesity drugs, drawing on experience of pharmacological development work, pre-clinical tests for anti-obesity efficacy, and clinical trials of candidate anti-obesity compounds Includes bibliographical references and index Aufsatzsammlung swd Obésité / Aspect psychologique Appétit Poids corporel MEDICAL / Bariatrics bisacsh Vetzucht gtt Geneesmiddelen gtt Essgewohnheit swd Physiologie swd Psychopharmakon swd Übergewicht swd Appetite fast Body weight fast Obesity / Psychological aspects fast Essgewohnheit gnd Physiologie gnd Psychopharmakon gnd Übergewicht gnd Anti-Obesity Agents Appetite Body Weight Obesity / physiopathology Medizin Psychologie Obesity Psychological aspects Body weight Physiologie (DE-588)4045981-0 gnd rswk-swf Übergewicht (DE-588)4061388-4 gnd rswk-swf Psychopharmakon (DE-588)4047729-0 gnd rswk-swf Essgewohnheit (DE-588)4139275-9 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Übergewicht (DE-588)4061388-4 s Psychopharmakon (DE-588)4047729-0 s 2\p DE-604 Essgewohnheit (DE-588)4139275-9 s Physiologie (DE-588)4045981-0 s 3\p DE-604 Kirkham, Tim C. Sonstige oth Cooper, S. J. Sonstige oth http://www.sciencedirect.com/science/book/9780123706331 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Appetite and body weight integrative systems and the development of anti-obesity drugs Aufsatzsammlung swd Obésité / Aspect psychologique Appétit Poids corporel MEDICAL / Bariatrics bisacsh Vetzucht gtt Geneesmiddelen gtt Essgewohnheit swd Physiologie swd Psychopharmakon swd Übergewicht swd Appetite fast Body weight fast Obesity / Psychological aspects fast Essgewohnheit gnd Physiologie gnd Psychopharmakon gnd Übergewicht gnd Anti-Obesity Agents Appetite Body Weight Obesity / physiopathology Medizin Psychologie Obesity Psychological aspects Body weight Physiologie (DE-588)4045981-0 gnd Übergewicht (DE-588)4061388-4 gnd Psychopharmakon (DE-588)4047729-0 gnd Essgewohnheit (DE-588)4139275-9 gnd |
| subject_GND | (DE-588)4045981-0 (DE-588)4061388-4 (DE-588)4047729-0 (DE-588)4139275-9 (DE-588)4143413-4 |
| title | Appetite and body weight integrative systems and the development of anti-obesity drugs |
| title_auth | Appetite and body weight integrative systems and the development of anti-obesity drugs |
| title_exact_search | Appetite and body weight integrative systems and the development of anti-obesity drugs |
| title_full | Appetite and body weight integrative systems and the development of anti-obesity drugs edited by Tim C. Kirkham and Steven J. Cooper |
| title_fullStr | Appetite and body weight integrative systems and the development of anti-obesity drugs edited by Tim C. Kirkham and Steven J. Cooper |
| title_full_unstemmed | Appetite and body weight integrative systems and the development of anti-obesity drugs edited by Tim C. Kirkham and Steven J. Cooper |
| title_short | Appetite and body weight |
| title_sort | appetite and body weight integrative systems and the development of anti obesity drugs |
| title_sub | integrative systems and the development of anti-obesity drugs |
| topic | Aufsatzsammlung swd Obésité / Aspect psychologique Appétit Poids corporel MEDICAL / Bariatrics bisacsh Vetzucht gtt Geneesmiddelen gtt Essgewohnheit swd Physiologie swd Psychopharmakon swd Übergewicht swd Appetite fast Body weight fast Obesity / Psychological aspects fast Essgewohnheit gnd Physiologie gnd Psychopharmakon gnd Übergewicht gnd Anti-Obesity Agents Appetite Body Weight Obesity / physiopathology Medizin Psychologie Obesity Psychological aspects Body weight Physiologie (DE-588)4045981-0 gnd Übergewicht (DE-588)4061388-4 gnd Psychopharmakon (DE-588)4047729-0 gnd Essgewohnheit (DE-588)4139275-9 gnd |
| topic_facet | Aufsatzsammlung Obésité / Aspect psychologique Appétit Poids corporel MEDICAL / Bariatrics Vetzucht Geneesmiddelen Essgewohnheit Physiologie Psychopharmakon Übergewicht Appetite Body weight Obesity / Psychological aspects Anti-Obesity Agents Body Weight Obesity / physiopathology Medizin Psychologie Obesity Psychological aspects |
| url | http://www.sciencedirect.com/science/book/9780123706331 |
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