Cancer immunotherapy: immune suppression and tumor growth
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Academic Press/Elsevier
c2007
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumoral immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease. * Offers a synthesis of concepts that are useful to cancer immunologists and pharmacologists, who tend to work in disparate fields with little cross-communication * Drs Prendergast and Jaffee are internationally recognized leaders in cancer biology and immunology who have created a unique synthesis of fundamental and applied concepts in this important new area of cancer research * Summarizes the latest insights into how immune escape defines an essential trait of cancer * Includes numerous illustrations including: how molecular-targeted therapeutic drugs or traditional chemotherapy can be combined with immunotherapy to improve anti-tumor efficacy; and how reversing immune suppression by the tumor can cause tumor regression Includes bibliographical references and index |
| Beschreibung: | 1 Online-Ressource (xiii, 409 p., [4] p. of plates) |
| ISBN: | 9780123725516 0123725518 9780080521855 0080521851 |
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| 500 | |a There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumoral immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease. * Offers a synthesis of concepts that are useful to cancer immunologists and pharmacologists, who tend to work in disparate fields with little cross-communication * Drs Prendergast and Jaffee are internationally recognized leaders in cancer biology and immunology who have created a unique synthesis of fundamental and applied concepts in this important new area of cancer research * Summarizes the latest insights into how immune escape defines an essential trait of cancer * Includes numerous illustrations including: how molecular-targeted therapeutic drugs or traditional chemotherapy can be combined with immunotherapy to improve anti-tumor efficacy; and how reversing immune suppression by the tumor can cause tumor regression | ||
| 500 | |a Includes bibliographical references and index | ||
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| 650 | 7 | |a HEALTH & FITNESS / Diseases / Cancer |2 bisacsh | |
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| 650 | 7 | |a Cancer / Immunotherapy |2 fast | |
| 650 | 7 | |a Tumors / Immunological aspects |2 fast | |
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| 650 | 4 | |a Cancer |x Immunotherapy | |
| 650 | 4 | |a Antineoplastic agents |x Therapeutic use | |
| 650 | 4 | |a Tumors |x Immunological aspects | |
| 700 | 1 | |a Prendergast, George C. |e Sonstige |4 oth | |
| 700 | 1 | |a Jaffee, Elizabeth M. |e Sonstige |4 oth | |
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| dewey-ones | 616 - Diseases |
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| discipline | Medizin |
| format | Electronic eBook |
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| id | DE-604.BV042310048 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:18:01Z |
| institution | BVB |
| isbn | 9780123725516 0123725518 9780080521855 0080521851 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027747040 |
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| owner_facet | DE-1046 |
| physical | 1 Online-Ressource (xiii, 409 p., [4] p. of plates) |
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| publishDate | 2007 |
| publishDateSearch | 2007 |
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| publisher | Academic Press/Elsevier |
| record_format | marc |
| spelling | Cancer immunotherapy immune suppression and tumor growth edited by George Prendergast, Elizabeth M. Jaffee Amsterdam Academic Press/Elsevier c2007 1 Online-Ressource (xiii, 409 p., [4] p. of plates) txt rdacontent c rdamedia cr rdacarrier There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumoral immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease. * Offers a synthesis of concepts that are useful to cancer immunologists and pharmacologists, who tend to work in disparate fields with little cross-communication * Drs Prendergast and Jaffee are internationally recognized leaders in cancer biology and immunology who have created a unique synthesis of fundamental and applied concepts in this important new area of cancer research * Summarizes the latest insights into how immune escape defines an essential trait of cancer * Includes numerous illustrations including: how molecular-targeted therapeutic drugs or traditional chemotherapy can be combined with immunotherapy to improve anti-tumor efficacy; and how reversing immune suppression by the tumor can cause tumor regression Includes bibliographical references and index MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Antineoplastic agents / Therapeutic use fast Cancer / Immunotherapy fast Tumors / Immunological aspects fast Neoplasms / therapy Antineoplastic Agents / therapeutic use Immunotherapy / methods Medizin Cancer Immunotherapy Antineoplastic agents Therapeutic use Tumors Immunological aspects Prendergast, George C. Sonstige oth Jaffee, Elizabeth M. Sonstige oth http://www.sciencedirect.com/science/book/9780123725516 Verlag Volltext |
| spellingShingle | Cancer immunotherapy immune suppression and tumor growth MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Antineoplastic agents / Therapeutic use fast Cancer / Immunotherapy fast Tumors / Immunological aspects fast Neoplasms / therapy Antineoplastic Agents / therapeutic use Immunotherapy / methods Medizin Cancer Immunotherapy Antineoplastic agents Therapeutic use Tumors Immunological aspects |
| title | Cancer immunotherapy immune suppression and tumor growth |
| title_auth | Cancer immunotherapy immune suppression and tumor growth |
| title_exact_search | Cancer immunotherapy immune suppression and tumor growth |
| title_full | Cancer immunotherapy immune suppression and tumor growth edited by George Prendergast, Elizabeth M. Jaffee |
| title_fullStr | Cancer immunotherapy immune suppression and tumor growth edited by George Prendergast, Elizabeth M. Jaffee |
| title_full_unstemmed | Cancer immunotherapy immune suppression and tumor growth edited by George Prendergast, Elizabeth M. Jaffee |
| title_short | Cancer immunotherapy |
| title_sort | cancer immunotherapy immune suppression and tumor growth |
| title_sub | immune suppression and tumor growth |
| topic | MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Antineoplastic agents / Therapeutic use fast Cancer / Immunotherapy fast Tumors / Immunological aspects fast Neoplasms / therapy Antineoplastic Agents / therapeutic use Immunotherapy / methods Medizin Cancer Immunotherapy Antineoplastic agents Therapeutic use Tumors Immunological aspects |
| topic_facet | MEDICAL / Oncology HEALTH & FITNESS / Diseases / Cancer Antineoplastic agents / Therapeutic use Cancer / Immunotherapy Tumors / Immunological aspects Neoplasms / therapy Antineoplastic Agents / therapeutic use Immunotherapy / methods Medizin Cancer Immunotherapy Antineoplastic agents Therapeutic use Tumors Immunological aspects |
| url | http://www.sciencedirect.com/science/book/9780123725516 |
| work_keys_str_mv | AT prendergastgeorgec cancerimmunotherapyimmunesuppressionandtumorgrowth AT jaffeeelizabethm cancerimmunotherapyimmunesuppressionandtumorgrowth |