Interleukin-1 in the brain:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Oxford
Pergamon Press
1992
|
| Ausgabe: | 1st ed |
| Schriftenreihe: | Pergamon studies in neuroscience
no. 5 |
| Schlagworte: | |
| Online-Zugang: | FAW01 Volltext |
| Beschreibung: | Includes bibliographical references and index Interest in interleukin-1 (IL-1) has increased dramatically over the last decade, but has been largely restricted to immunologists, cell biologists and those studying inflammation and cancer. However, it has recently been recognized that the brain directly controls or modulates many aspects of immune function, while molecules classically associated with the immune system, such as interleukin-1, are synthesised within the brain and act directly on the central nervous system to modify local and systemic functions. Thus, this topic is relatively new to neurobiologists, and this book is the first comprehensive description of current knowledge on interleukin-1 in the brain, including its location, synthesis and receptors, actions on behaviour, fever, metabolism, neuroendocrine function, electrical activity of the brain, nerve growth factor, and relationship to clinical indications. The book is organised into three sections. The first reviews the data available on the neural localisation of IL-1 and the nature of its central receptors. The main part of the book examines the different neural effects of IL-1 and the mechanisms which are involved in these actions, comparing IL-1 where possible to other inflammatory cytokines which also have neurotrophic effects. The final section evaluates the possible role of IL-1 in neural plasticity and neuronal degeneration |
| Beschreibung: | 1 Online-Ressource (viii, 207 pages) |
| ISBN: | 0080419968 9780080419961 |
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| 500 | |a Interest in interleukin-1 (IL-1) has increased dramatically over the last decade, but has been largely restricted to immunologists, cell biologists and those studying inflammation and cancer. However, it has recently been recognized that the brain directly controls or modulates many aspects of immune function, while molecules classically associated with the immune system, such as interleukin-1, are synthesised within the brain and act directly on the central nervous system to modify local and systemic functions. Thus, this topic is relatively new to neurobiologists, and this book is the first comprehensive description of current knowledge on interleukin-1 in the brain, including its location, synthesis and receptors, actions on behaviour, fever, metabolism, neuroendocrine function, electrical activity of the brain, nerve growth factor, and relationship to clinical indications. The book is organised into three sections. The first reviews the data available on the neural localisation of IL-1 and the nature of its central receptors. The main part of the book examines the different neural effects of IL-1 and the mechanisms which are involved in these actions, comparing IL-1 where possible to other inflammatory cytokines which also have neurotrophic effects. The final section evaluates the possible role of IL-1 in neural plasticity and neuronal degeneration | ||
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Datensatz im Suchindex
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|---|---|
| any_adam_object | |
| building | Verbundindex |
| bvnumber | BV042309568 |
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| dewey-full | 612.8/042 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.8/042 |
| dewey-search | 612.8/042 |
| dewey-sort | 3612.8 242 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 1st ed |
| format | Electronic eBook |
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| genre_facet | Aufsatzsammlung |
| id | DE-604.BV042309568 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:18:00Z |
| institution | BVB |
| isbn | 0080419968 9780080419961 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027746560 |
| oclc_num | 681891401 |
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| owner_facet | DE-1046 |
| physical | 1 Online-Ressource (viii, 207 pages) |
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| publishDate | 1992 |
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| spelling | Interleukin-1 in the brain edited by Nancy Rothwell and Robert Dantzer 1st ed Oxford Pergamon Press 1992 1 Online-Ressource (viii, 207 pages) txt rdacontent c rdamedia cr rdacarrier Pergamon studies in neuroscience no. 5 Includes bibliographical references and index Interest in interleukin-1 (IL-1) has increased dramatically over the last decade, but has been largely restricted to immunologists, cell biologists and those studying inflammation and cancer. However, it has recently been recognized that the brain directly controls or modulates many aspects of immune function, while molecules classically associated with the immune system, such as interleukin-1, are synthesised within the brain and act directly on the central nervous system to modify local and systemic functions. Thus, this topic is relatively new to neurobiologists, and this book is the first comprehensive description of current knowledge on interleukin-1 in the brain, including its location, synthesis and receptors, actions on behaviour, fever, metabolism, neuroendocrine function, electrical activity of the brain, nerve growth factor, and relationship to clinical indications. The book is organised into three sections. The first reviews the data available on the neural localisation of IL-1 and the nature of its central receptors. The main part of the book examines the different neural effects of IL-1 and the mechanisms which are involved in these actions, comparing IL-1 where possible to other inflammatory cytokines which also have neurotrophic effects. The final section evaluates the possible role of IL-1 in neural plasticity and neuronal degeneration Humans / Brain Brain / metabolism Interleukin-1 / metabolism Cerveau Interleukine 1 Interleukin 1 swd Zentralnervensystem swd Aufsatzsammlung swd Hirnstoffwechsel swd Brain fast Interleukin-1 fast Brain Interleukin-1 Interleukin 1 (DE-588)4212777-4 gnd rswk-swf Hirnstoffwechsel (DE-588)4195457-9 gnd rswk-swf Zentralnervensystem (DE-588)4067637-7 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Interleukin 1 (DE-588)4212777-4 s Zentralnervensystem (DE-588)4067637-7 s 2\p DE-604 Hirnstoffwechsel (DE-588)4195457-9 s 3\p DE-604 Rothwell, Nancy Sonstige oth Dantzer, Robert Sonstige oth http://www.sciencedirect.com/science/book/9780080419961 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Interleukin-1 in the brain Humans / Brain Brain / metabolism Interleukin-1 / metabolism Cerveau Interleukine 1 Interleukin 1 swd Zentralnervensystem swd Aufsatzsammlung swd Hirnstoffwechsel swd Brain fast Interleukin-1 fast Brain Interleukin-1 Interleukin 1 (DE-588)4212777-4 gnd Hirnstoffwechsel (DE-588)4195457-9 gnd Zentralnervensystem (DE-588)4067637-7 gnd |
| subject_GND | (DE-588)4212777-4 (DE-588)4195457-9 (DE-588)4067637-7 (DE-588)4143413-4 |
| title | Interleukin-1 in the brain |
| title_auth | Interleukin-1 in the brain |
| title_exact_search | Interleukin-1 in the brain |
| title_full | Interleukin-1 in the brain edited by Nancy Rothwell and Robert Dantzer |
| title_fullStr | Interleukin-1 in the brain edited by Nancy Rothwell and Robert Dantzer |
| title_full_unstemmed | Interleukin-1 in the brain edited by Nancy Rothwell and Robert Dantzer |
| title_short | Interleukin-1 in the brain |
| title_sort | interleukin 1 in the brain |
| topic | Humans / Brain Brain / metabolism Interleukin-1 / metabolism Cerveau Interleukine 1 Interleukin 1 swd Zentralnervensystem swd Aufsatzsammlung swd Hirnstoffwechsel swd Brain fast Interleukin-1 fast Brain Interleukin-1 Interleukin 1 (DE-588)4212777-4 gnd Hirnstoffwechsel (DE-588)4195457-9 gnd Zentralnervensystem (DE-588)4067637-7 gnd |
| topic_facet | Humans / Brain Brain / metabolism Interleukin-1 / metabolism Cerveau Interleukine 1 Interleukin 1 Zentralnervensystem Aufsatzsammlung Hirnstoffwechsel Brain Interleukin-1 |
| url | http://www.sciencedirect.com/science/book/9780080419961 |
| work_keys_str_mv | AT rothwellnancy interleukin1inthebrain AT dantzerrobert interleukin1inthebrain |