Bioseparation of proteins: unfolding/folding and validations
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
San Diego
Academic Press
c1998
|
| Schriftenreihe: | Separation science and technology (San Diego, Calif.)
v. 1 |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | This book covers the fundamentals of protein inactivation during bioseparation and the effect on protein processing. Bioseparation of Proteins is unique because it provides a background of the bioseparation processes, and it is the first book available to emphasize the influence of the different bioseparation processes on protein inactivation. Bioseparation of Proteins covers the extent, mechanisms of, and control of protein inactivation during these processes along with the subsequent and essential validation of these processes. The book focuses on the avoidance of protein (biologicalproduct) inactivation at each step in a bioprocess. It compares protein inactivation exhibited during the different bioseparation processes by different workers and provides a valuable framework for workers in different areas interested in bioseparations. Topics include separation and detection methods; estimates of protein inactivation and an analysis of this problem for different separation processes; strategies for avoiding inactivation; the molecular basis of surface activity and protein adsorption, process monitoring, and product validation techniques; and the economics of various bioseparation processes and quality control procedures. Key Features * Protein inactivation and other aspects of biological stability are critical to an effective bioseparation process; This book is a detailed and critical review of the available literature in an area that is essential to the effectiveness, validation, and economics of bioseparation processes for drugs and other biological products; Conveniently assembled under one cover, the survey of the literature and resulting perspective will greatly assist engineers and chemists in designingand improving their own processes; Key features of the text include: * detailed data on biological stability under various bioseparation conditions * extensive case studies from the literature on separation processes, validation, and economics * simplified analysis of protein refolding and inactivation mechanisms * consideration of adsorption theories and the effect of heterogeneity * coverage of both classical and novel bioseparation techniques, including chromatographic procedures Includes bibliographical references and index |
| Beschreibung: | 1 Online-Ressource (xx, 346 p.) |
| ISBN: | 9780126140408 0126140405 9780080528144 0080528147 |
Internformat
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| 490 | 0 | |a Separation science and technology (San Diego, Calif.) |v v. 1 | |
| 500 | |a This book covers the fundamentals of protein inactivation during bioseparation and the effect on protein processing. Bioseparation of Proteins is unique because it provides a background of the bioseparation processes, and it is the first book available to emphasize the influence of the different bioseparation processes on protein inactivation. Bioseparation of Proteins covers the extent, mechanisms of, and control of protein inactivation during these processes along with the subsequent and essential validation of these processes. The book focuses on the avoidance of protein (biologicalproduct) inactivation at each step in a bioprocess. It compares protein inactivation exhibited during the different bioseparation processes by different workers and provides a valuable framework for workers in different areas interested in bioseparations. | ||
| 500 | |a Topics include separation and detection methods; estimates of protein inactivation and an analysis of this problem for different separation processes; strategies for avoiding inactivation; the molecular basis of surface activity and protein adsorption, process monitoring, and product validation techniques; and the economics of various bioseparation processes and quality control procedures. | ||
| 500 | |a Key Features * Protein inactivation and other aspects of biological stability are critical to an effective bioseparation process; This book is a detailed and critical review of the available literature in an area that is essential to the effectiveness, validation, and economics of bioseparation processes for drugs and other biological products; Conveniently assembled under one cover, the survey of the literature and resulting perspective will greatly assist engineers and chemists in designingand improving their own processes; Key features of the text include: * detailed data on biological stability under various bioseparation conditions * extensive case studies from the literature on separation processes, validation, and economics * simplified analysis of protein refolding and inactivation mechanisms * consideration of adsorption theories and the effect of heterogeneity * coverage of both classical and novel bioseparation techniques, including chromatographic procedures | ||
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Proteins / isolation & purification | |
| 650 | 4 | |a Biotechnology / methods | |
| 650 | 4 | |a Protein Folding | |
| 650 | 7 | |a SCIENCE / Biotechnology |2 bisacsh | |
| 650 | 7 | |a Protein folding |2 fast | |
| 650 | 7 | |a Proteins / Biotechnology |2 fast | |
| 650 | 7 | |a Proteins / Separation |2 fast | |
| 650 | 4 | |a Proteins |x Biotechnology | |
| 650 | 4 | |a Proteins |x Separation | |
| 650 | 4 | |a Protein folding | |
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Datensatz im Suchindex
| _version_ | 1804152894625153024 |
|---|---|
| any_adam_object | |
| author | Sadana, Ajit |
| author_facet | Sadana, Ajit |
| author_role | aut |
| author_sort | Sadana, Ajit |
| author_variant | a s as |
| building | Verbundindex |
| bvnumber | BV042308330 |
| collection | ZDB-33-ESD ZDB-33-EBS |
| ctrlnum | (OCoLC)162576678 (DE-599)BVBBV042308330 |
| dewey-full | 660.6/3 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 660 - Chemical engineering |
| dewey-raw | 660.6/3 |
| dewey-search | 660.6/3 |
| dewey-sort | 3660.6 13 |
| dewey-tens | 660 - Chemical engineering |
| discipline | Chemie / Pharmazie |
| format | Electronic eBook |
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| id | DE-604.BV042308330 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:17:58Z |
| institution | BVB |
| isbn | 9780126140408 0126140405 9780080528144 0080528147 |
| language | English |
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| physical | 1 Online-Ressource (xx, 346 p.) |
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| publishDate | 1998 |
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| publisher | Academic Press |
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| series2 | Separation science and technology (San Diego, Calif.) |
| spelling | Sadana, Ajit Verfasser aut Bioseparation of proteins unfolding/folding and validations Ajit Sadana San Diego Academic Press c1998 1 Online-Ressource (xx, 346 p.) txt rdacontent c rdamedia cr rdacarrier Separation science and technology (San Diego, Calif.) v. 1 This book covers the fundamentals of protein inactivation during bioseparation and the effect on protein processing. Bioseparation of Proteins is unique because it provides a background of the bioseparation processes, and it is the first book available to emphasize the influence of the different bioseparation processes on protein inactivation. Bioseparation of Proteins covers the extent, mechanisms of, and control of protein inactivation during these processes along with the subsequent and essential validation of these processes. The book focuses on the avoidance of protein (biologicalproduct) inactivation at each step in a bioprocess. It compares protein inactivation exhibited during the different bioseparation processes by different workers and provides a valuable framework for workers in different areas interested in bioseparations. Topics include separation and detection methods; estimates of protein inactivation and an analysis of this problem for different separation processes; strategies for avoiding inactivation; the molecular basis of surface activity and protein adsorption, process monitoring, and product validation techniques; and the economics of various bioseparation processes and quality control procedures. Key Features * Protein inactivation and other aspects of biological stability are critical to an effective bioseparation process; This book is a detailed and critical review of the available literature in an area that is essential to the effectiveness, validation, and economics of bioseparation processes for drugs and other biological products; Conveniently assembled under one cover, the survey of the literature and resulting perspective will greatly assist engineers and chemists in designingand improving their own processes; Key features of the text include: * detailed data on biological stability under various bioseparation conditions * extensive case studies from the literature on separation processes, validation, and economics * simplified analysis of protein refolding and inactivation mechanisms * consideration of adsorption theories and the effect of heterogeneity * coverage of both classical and novel bioseparation techniques, including chromatographic procedures Includes bibliographical references and index Proteins / isolation & purification Biotechnology / methods Protein Folding SCIENCE / Biotechnology bisacsh Protein folding fast Proteins / Biotechnology fast Proteins / Separation fast Proteins Biotechnology Proteins Separation Protein folding Proteine (DE-588)4076388-2 gnd rswk-swf Biotechnologie (DE-588)4069491-4 gnd rswk-swf Trennverfahren (DE-588)4078395-9 gnd rswk-swf Proteine (DE-588)4076388-2 s Trennverfahren (DE-588)4078395-9 s Biotechnologie (DE-588)4069491-4 s 1\p DE-604 http://www.sciencedirect.com/science/book/9780126140408 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Sadana, Ajit Bioseparation of proteins unfolding/folding and validations Proteins / isolation & purification Biotechnology / methods Protein Folding SCIENCE / Biotechnology bisacsh Protein folding fast Proteins / Biotechnology fast Proteins / Separation fast Proteins Biotechnology Proteins Separation Protein folding Proteine (DE-588)4076388-2 gnd Biotechnologie (DE-588)4069491-4 gnd Trennverfahren (DE-588)4078395-9 gnd |
| subject_GND | (DE-588)4076388-2 (DE-588)4069491-4 (DE-588)4078395-9 |
| title | Bioseparation of proteins unfolding/folding and validations |
| title_auth | Bioseparation of proteins unfolding/folding and validations |
| title_exact_search | Bioseparation of proteins unfolding/folding and validations |
| title_full | Bioseparation of proteins unfolding/folding and validations Ajit Sadana |
| title_fullStr | Bioseparation of proteins unfolding/folding and validations Ajit Sadana |
| title_full_unstemmed | Bioseparation of proteins unfolding/folding and validations Ajit Sadana |
| title_short | Bioseparation of proteins |
| title_sort | bioseparation of proteins unfolding folding and validations |
| title_sub | unfolding/folding and validations |
| topic | Proteins / isolation & purification Biotechnology / methods Protein Folding SCIENCE / Biotechnology bisacsh Protein folding fast Proteins / Biotechnology fast Proteins / Separation fast Proteins Biotechnology Proteins Separation Protein folding Proteine (DE-588)4076388-2 gnd Biotechnologie (DE-588)4069491-4 gnd Trennverfahren (DE-588)4078395-9 gnd |
| topic_facet | Proteins / isolation & purification Biotechnology / methods Protein Folding SCIENCE / Biotechnology Protein folding Proteins / Biotechnology Proteins / Separation Proteins Biotechnology Proteins Separation Proteine Biotechnologie Trennverfahren |
| url | http://www.sciencedirect.com/science/book/9780126140408 |
| work_keys_str_mv | AT sadanaajit bioseparationofproteinsunfoldingfoldingandvalidations |