Medicinal chemistry of anticancer drugs:
Gespeichert in:
1. Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Amsterdam
Elsevier
2008
|
Ausgabe: | 1st ed |
Schlagworte: | |
Online-Zugang: | Volltext |
Beschreibung: | Antitumour chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells. These therapies are in their infancy, but they hold promise of more effective therapies with fewer side effects. Resistance to antitumour drugs is another important but normally neglected field. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumour drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumour agents, aiming at the rationalization of the action of this type of drugs, which would allow the design of new active structures. * Presents information in a clear and concise way using a large number of figures * Historical background provides insights on how the process of drug discovery in the anticancer field has evolved * Extensive references to primary literature Includes bibliographical references and index |
Beschreibung: | 1 Online-Ressource (xv, 442 p.) |
ISBN: | 9780444528247 0444528245 9780080570327 0080570321 |
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500 | |a Antitumour chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells. These therapies are in their infancy, but they hold promise of more effective therapies with fewer side effects. Resistance to antitumour drugs is another important but normally neglected field. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumour drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumour agents, aiming at the rationalization of the action of this type of drugs, which would allow the design of new active structures. * Presents information in a clear and concise way using a large number of figures * Historical background provides insights on how the process of drug discovery in the anticancer field has evolved * Extensive references to primary literature | ||
500 | |a Includes bibliographical references and index | ||
650 | 7 | |a Cancer / Chemotherapy |2 fast | |
650 | 7 | |a Drugs / Design |2 fast | |
650 | 7 | |a Pharmaceutical chemistry |2 fast | |
650 | 7 | |a MEDICAL / Oncology |2 bisacsh | |
650 | 7 | |a HEALTH & FITNESS / Diseases / Cancer |2 bisacsh | |
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Datensatz im Suchindex
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any_adam_object | |
author | Avendaño, Carmen |
author_facet | Avendaño, Carmen |
author_role | aut |
author_sort | Avendaño, Carmen |
author_variant | c a ca |
building | Verbundindex |
bvnumber | BV042307298 |
collection | ZDB-33-ESD ZDB-33-EBS |
ctrlnum | (OCoLC)272382250 (DE-599)BVBBV042307298 |
dewey-full | 616.994061 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 616 - Diseases |
dewey-raw | 616.994061 |
dewey-search | 616.994061 |
dewey-sort | 3616.994061 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
edition | 1st ed |
format | Electronic eBook |
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id | DE-604.BV042307298 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T01:17:56Z |
institution | BVB |
isbn | 9780444528247 0444528245 9780080570327 0080570321 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027744290 |
oclc_num | 272382250 |
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owner_facet | DE-1046 |
physical | 1 Online-Ressource (xv, 442 p.) |
psigel | ZDB-33-ESD ZDB-33-EBS FAW_PDA_ESD FLA_PDA_ESD |
publishDate | 2008 |
publishDateSearch | 2008 |
publishDateSort | 2008 |
publisher | Elsevier |
record_format | marc |
spelling | Avendaño, Carmen Verfasser aut Medicinal chemistry of anticancer drugs Carmen Avendaño and J. Carlos Menéndez 1st ed Amsterdam Elsevier 2008 1 Online-Ressource (xv, 442 p.) txt rdacontent c rdamedia cr rdacarrier Antitumour chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells. These therapies are in their infancy, but they hold promise of more effective therapies with fewer side effects. Resistance to antitumour drugs is another important but normally neglected field. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumour drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumour agents, aiming at the rationalization of the action of this type of drugs, which would allow the design of new active structures. * Presents information in a clear and concise way using a large number of figures * Historical background provides insights on how the process of drug discovery in the anticancer field has evolved * Extensive references to primary literature Includes bibliographical references and index Cancer / Chemotherapy fast Drugs / Design fast Pharmaceutical chemistry fast MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Medizin Cancer Chemotherapy Drugs Design Pharmaceutical chemistry Menéndez, J. Carlos Sonstige oth http://www.sciencedirect.com/science/book/9780444528247 Verlag Volltext |
spellingShingle | Avendaño, Carmen Medicinal chemistry of anticancer drugs Cancer / Chemotherapy fast Drugs / Design fast Pharmaceutical chemistry fast MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Medizin Cancer Chemotherapy Drugs Design Pharmaceutical chemistry |
title | Medicinal chemistry of anticancer drugs |
title_auth | Medicinal chemistry of anticancer drugs |
title_exact_search | Medicinal chemistry of anticancer drugs |
title_full | Medicinal chemistry of anticancer drugs Carmen Avendaño and J. Carlos Menéndez |
title_fullStr | Medicinal chemistry of anticancer drugs Carmen Avendaño and J. Carlos Menéndez |
title_full_unstemmed | Medicinal chemistry of anticancer drugs Carmen Avendaño and J. Carlos Menéndez |
title_short | Medicinal chemistry of anticancer drugs |
title_sort | medicinal chemistry of anticancer drugs |
topic | Cancer / Chemotherapy fast Drugs / Design fast Pharmaceutical chemistry fast MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Medizin Cancer Chemotherapy Drugs Design Pharmaceutical chemistry |
topic_facet | Cancer / Chemotherapy Drugs / Design Pharmaceutical chemistry MEDICAL / Oncology HEALTH & FITNESS / Diseases / Cancer Medizin Cancer Chemotherapy Drugs Design |
url | http://www.sciencedirect.com/science/book/9780444528247 |
work_keys_str_mv | AT avendanocarmen medicinalchemistryofanticancerdrugs AT menendezjcarlos medicinalchemistryofanticancerdrugs |