Pharmacology in drug discovery: understanding drug response
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Academic Press
2012
|
| Schlagworte: | |
| Online-Zugang: | FUBA1 Volltext |
| Beschreibung: | Pharmacology in Drug Discovery: Understanding Drug Response is designed for all students, recent graduates, and new researchers in the pharmaceutical and biotechnology industries who need to interpret change in physiology induced by a chemical substance. Physiological systems customize chemical signal input to their own needs; therefore, the same drug can have different effects in different physiological systems. The field of pharmacology is unique in that it furnishes the tools to analyze these different behaviors and traces them to their root cause. This enables predictions of drug behavior to be made in all systems, an invaluable tool for drug discovery because almost all drugs are developed in test systems far removed from the therapeutic one. This valuable resource provides simple explanations of the ways in which biological systems use basic biochemical mechanisms to produce fine chemical control of physiology, allowing for more informed predictions of drug effects in all systems and forming the basis of the drug-discovery process. Chapters follow a logical progression on how to characterize the pharmacology of any given molecule and include important terminology, chapter summaries, references, and review questions to aid the reader in understanding and retention of the material. Bridges the gap between biochemistry and therapeutic medicine Chapters include key topics such as drug affinity and efficacy, enzymes as drug targets, in vivo pharmacology, safety pharmacology, and more Enables the reader to interpret drug dose-response data and make mechanistic inferences at the molecular level |
| Beschreibung: | 1 Online-Ressource (XI, 247 S.) Ill., graph. Darst. |
| ISBN: | 9780123848567 0123848563 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV042307276 | ||
| 003 | DE-604 | ||
| 005 | 20210527 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 150129s2012 |||| o||u| ||||||eng d | ||
| 020 | |a 9780123848567 |c electronic bk. |9 978-0-12-384856-7 | ||
| 020 | |a 0123848563 |c electronic bk. |9 0-12-384856-3 | ||
| 024 | 7 | |a 10.1016/C2009-0-63928-3 |2 doi | |
| 035 | |a (OCoLC)756489918 | ||
| 035 | |a (DE-599)BVBBV042307276 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-1046 |a DE-188 | ||
| 082 | 0 | |a 615.1 |2 23 | |
| 100 | 1 | |a Kenakin, Terrence P. |d 1949- |e Verfasser |0 (DE-588)121921239 |4 aut | |
| 245 | 1 | 0 | |a Pharmacology in drug discovery |b understanding drug response |c Terry Kenakin |
| 264 | 1 | |a Amsterdam [u.a.] |b Academic Press |c 2012 | |
| 300 | |a 1 Online-Ressource (XI, 247 S.) |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 500 | |a Pharmacology in Drug Discovery: Understanding Drug Response is designed for all students, recent graduates, and new researchers in the pharmaceutical and biotechnology industries who need to interpret change in physiology induced by a chemical substance. Physiological systems customize chemical signal input to their own needs; therefore, the same drug can have different effects in different physiological systems. The field of pharmacology is unique in that it furnishes the tools to analyze these different behaviors and traces them to their root cause. This enables predictions of drug behavior to be made in all systems, an invaluable tool for drug discovery because almost all drugs are developed in test systems far removed from the therapeutic one. This valuable resource provides simple explanations of the ways in which biological systems use basic biochemical mechanisms to produce fine chemical control of physiology, allowing for more informed predictions of drug effects in all systems and forming the basis of the drug-discovery process. Chapters follow a logical progression on how to characterize the pharmacology of any given molecule and include important terminology, chapter summaries, references, and review questions to aid the reader in understanding and retention of the material. Bridges the gap between biochemistry and therapeutic medicine Chapters include key topics such as drug affinity and efficacy, enzymes as drug targets, in vivo pharmacology, safety pharmacology, and more Enables the reader to interpret drug dose-response data and make mechanistic inferences at the molecular level | ||
| 650 | 7 | |a Drug development |2 fast | |
| 650 | 7 | |a Pharmacology |2 fast | |
| 650 | 4 | |a Pharmacology | |
| 650 | 4 | |a Drug development | |
| 650 | 0 | 7 | |a Pharmakologie |0 (DE-588)4045687-0 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Arzneimittelentwicklung |0 (DE-588)4143176-5 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Arzneimittelentwicklung |0 (DE-588)4143176-5 |D s |
| 689 | 0 | 1 | |a Pharmakologie |0 (DE-588)4045687-0 |D s |
| 689 | 0 | |5 DE-604 | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 978-0-12-384856-7 |w (DE-604)BV040424170 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 0-12-384856-3 |w (DE-604)BV040424170 |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/book/9780123848567 |x Verlag |3 Volltext |
| 912 | |a ZDB-33-ESD |a ZDB-33-EBS | ||
| 940 | 1 | |q FAW_PDA_ESD | |
| 940 | 1 | |q FLA_PDA_ESD | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-027744268 | ||
| 966 | e | |u http://www.sciencedirect.com/science/book/9780123848567 |l FUBA1 |p ZDB-33-ESD |q ZDB-33-ESD 2013 |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804152892371763200 |
|---|---|
| any_adam_object | |
| author | Kenakin, Terrence P. 1949- |
| author_GND | (DE-588)121921239 |
| author_facet | Kenakin, Terrence P. 1949- |
| author_role | aut |
| author_sort | Kenakin, Terrence P. 1949- |
| author_variant | t p k tp tpk |
| building | Verbundindex |
| bvnumber | BV042307276 |
| collection | ZDB-33-ESD ZDB-33-EBS |
| ctrlnum | (OCoLC)756489918 (DE-599)BVBBV042307276 |
| dewey-full | 615.1 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.1 |
| dewey-search | 615.1 |
| dewey-sort | 3615.1 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03503nmm a2200493zc 4500</leader><controlfield tag="001">BV042307276</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20210527 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">150129s2012 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780123848567</subfield><subfield code="c">electronic bk.</subfield><subfield code="9">978-0-12-384856-7</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0123848563</subfield><subfield code="c">electronic bk.</subfield><subfield code="9">0-12-384856-3</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/C2009-0-63928-3</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)756489918</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV042307276</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-1046</subfield><subfield code="a">DE-188</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615.1</subfield><subfield code="2">23</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Kenakin, Terrence P.</subfield><subfield code="d">1949-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)121921239</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Pharmacology in drug discovery</subfield><subfield code="b">understanding drug response</subfield><subfield code="c">Terry Kenakin</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Amsterdam [u.a.]</subfield><subfield code="b">Academic Press</subfield><subfield code="c">2012</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XI, 247 S.)</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Pharmacology in Drug Discovery: Understanding Drug Response is designed for all students, recent graduates, and new researchers in the pharmaceutical and biotechnology industries who need to interpret change in physiology induced by a chemical substance. Physiological systems customize chemical signal input to their own needs; therefore, the same drug can have different effects in different physiological systems. The field of pharmacology is unique in that it furnishes the tools to analyze these different behaviors and traces them to their root cause. This enables predictions of drug behavior to be made in all systems, an invaluable tool for drug discovery because almost all drugs are developed in test systems far removed from the therapeutic one. This valuable resource provides simple explanations of the ways in which biological systems use basic biochemical mechanisms to produce fine chemical control of physiology, allowing for more informed predictions of drug effects in all systems and forming the basis of the drug-discovery process. Chapters follow a logical progression on how to characterize the pharmacology of any given molecule and include important terminology, chapter summaries, references, and review questions to aid the reader in understanding and retention of the material. Bridges the gap between biochemistry and therapeutic medicine Chapters include key topics such as drug affinity and efficacy, enzymes as drug targets, in vivo pharmacology, safety pharmacology, and more Enables the reader to interpret drug dose-response data and make mechanistic inferences at the molecular level</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Drug development</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Pharmacology</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Drug development</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Pharmakologie</subfield><subfield code="0">(DE-588)4045687-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Arzneimittelentwicklung</subfield><subfield code="0">(DE-588)4143176-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Arzneimittelentwicklung</subfield><subfield code="0">(DE-588)4143176-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Pharmakologie</subfield><subfield code="0">(DE-588)4045687-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">978-0-12-384856-7</subfield><subfield code="w">(DE-604)BV040424170</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">0-12-384856-3</subfield><subfield code="w">(DE-604)BV040424170</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.sciencedirect.com/science/book/9780123848567</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-33-ESD</subfield><subfield code="a">ZDB-33-EBS</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">FAW_PDA_ESD</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">FLA_PDA_ESD</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-027744268</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">http://www.sciencedirect.com/science/book/9780123848567</subfield><subfield code="l">FUBA1</subfield><subfield code="p">ZDB-33-ESD</subfield><subfield code="q">ZDB-33-ESD 2013</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV042307276 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T01:17:56Z |
| institution | BVB |
| isbn | 9780123848567 0123848563 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027744268 |
| oclc_num | 756489918 |
| open_access_boolean | |
| owner | DE-1046 DE-188 |
| owner_facet | DE-1046 DE-188 |
| physical | 1 Online-Ressource (XI, 247 S.) Ill., graph. Darst. |
| psigel | ZDB-33-ESD ZDB-33-EBS FAW_PDA_ESD FLA_PDA_ESD ZDB-33-ESD ZDB-33-ESD 2013 |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | Academic Press |
| record_format | marc |
| spelling | Kenakin, Terrence P. 1949- Verfasser (DE-588)121921239 aut Pharmacology in drug discovery understanding drug response Terry Kenakin Amsterdam [u.a.] Academic Press 2012 1 Online-Ressource (XI, 247 S.) Ill., graph. Darst. txt rdacontent c rdamedia cr rdacarrier Pharmacology in Drug Discovery: Understanding Drug Response is designed for all students, recent graduates, and new researchers in the pharmaceutical and biotechnology industries who need to interpret change in physiology induced by a chemical substance. Physiological systems customize chemical signal input to their own needs; therefore, the same drug can have different effects in different physiological systems. The field of pharmacology is unique in that it furnishes the tools to analyze these different behaviors and traces them to their root cause. This enables predictions of drug behavior to be made in all systems, an invaluable tool for drug discovery because almost all drugs are developed in test systems far removed from the therapeutic one. This valuable resource provides simple explanations of the ways in which biological systems use basic biochemical mechanisms to produce fine chemical control of physiology, allowing for more informed predictions of drug effects in all systems and forming the basis of the drug-discovery process. Chapters follow a logical progression on how to characterize the pharmacology of any given molecule and include important terminology, chapter summaries, references, and review questions to aid the reader in understanding and retention of the material. Bridges the gap between biochemistry and therapeutic medicine Chapters include key topics such as drug affinity and efficacy, enzymes as drug targets, in vivo pharmacology, safety pharmacology, and more Enables the reader to interpret drug dose-response data and make mechanistic inferences at the molecular level Drug development fast Pharmacology fast Pharmacology Drug development Pharmakologie (DE-588)4045687-0 gnd rswk-swf Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf Arzneimittelentwicklung (DE-588)4143176-5 s Pharmakologie (DE-588)4045687-0 s DE-604 Erscheint auch als Druck-Ausgabe 978-0-12-384856-7 (DE-604)BV040424170 Erscheint auch als Druck-Ausgabe 0-12-384856-3 (DE-604)BV040424170 http://www.sciencedirect.com/science/book/9780123848567 Verlag Volltext |
| spellingShingle | Kenakin, Terrence P. 1949- Pharmacology in drug discovery understanding drug response Drug development fast Pharmacology fast Pharmacology Drug development Pharmakologie (DE-588)4045687-0 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| subject_GND | (DE-588)4045687-0 (DE-588)4143176-5 |
| title | Pharmacology in drug discovery understanding drug response |
| title_auth | Pharmacology in drug discovery understanding drug response |
| title_exact_search | Pharmacology in drug discovery understanding drug response |
| title_full | Pharmacology in drug discovery understanding drug response Terry Kenakin |
| title_fullStr | Pharmacology in drug discovery understanding drug response Terry Kenakin |
| title_full_unstemmed | Pharmacology in drug discovery understanding drug response Terry Kenakin |
| title_short | Pharmacology in drug discovery |
| title_sort | pharmacology in drug discovery understanding drug response |
| title_sub | understanding drug response |
| topic | Drug development fast Pharmacology fast Pharmacology Drug development Pharmakologie (DE-588)4045687-0 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| topic_facet | Drug development Pharmacology Pharmakologie Arzneimittelentwicklung |
| url | http://www.sciencedirect.com/science/book/9780123848567 |
| work_keys_str_mv | AT kenakinterrencep pharmacologyindrugdiscoveryunderstandingdrugresponse |