Handbook of neuroemergency clinical trials:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Elsevier Academic Press
©2006
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | Includes bibliographical references and index During the 1990s, scientific advances in understanding the mechanisms and pathophysiology of acute central nervous system injury were offset by a history of disappointing results from Phase III clinical trials of novel neuroprotective drugs. Numerous novel compounds were tested, and seemingly fell by the wayside. This book is intended to focus on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. The authors explore the issues facing research in this area and the strategies that might lead to future success in this critical area of unmet medical need. It represents a compendium of information gained from over 20 years of clinical trial experience in areas of acute neurology and neurosurgery. From the knowledge of clinical assessment using standardized tools, to the intricate design of difficult hyper-acute neuroemergencies trials, the reader will benefit from the authors' perspectives |
| Beschreibung: | 1 Online-Ressource (xviii, 336 pages) |
| ISBN: | 9780126480825 0126480826 9780120885237 0120885239 0080454356 9780080454351 |
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| 500 | |a During the 1990s, scientific advances in understanding the mechanisms and pathophysiology of acute central nervous system injury were offset by a history of disappointing results from Phase III clinical trials of novel neuroprotective drugs. Numerous novel compounds were tested, and seemingly fell by the wayside. This book is intended to focus on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. The authors explore the issues facing research in this area and the strategies that might lead to future success in this critical area of unmet medical need. It represents a compendium of information gained from over 20 years of clinical trial experience in areas of acute neurology and neurosurgery. From the knowledge of clinical assessment using standardized tools, to the intricate design of difficult hyper-acute neuroemergencies trials, the reader will benefit from the authors' perspectives | ||
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| indexdate | 2024-08-14T00:53:40Z |
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| isbn | 9780126480825 0126480826 9780120885237 0120885239 0080454356 9780080454351 |
| language | English |
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| spelling | Handbook of neuroemergency clinical trials edited by Wayne M. Alves, Brett E. Skolnick Amsterdam Elsevier Academic Press ©2006 1 Online-Ressource (xviii, 336 pages) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index During the 1990s, scientific advances in understanding the mechanisms and pathophysiology of acute central nervous system injury were offset by a history of disappointing results from Phase III clinical trials of novel neuroprotective drugs. Numerous novel compounds were tested, and seemingly fell by the wayside. This book is intended to focus on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. The authors explore the issues facing research in this area and the strategies that might lead to future success in this critical area of unmet medical need. It represents a compendium of information gained from over 20 years of clinical trial experience in areas of acute neurology and neurosurgery. From the knowledge of clinical assessment using standardized tools, to the intricate design of difficult hyper-acute neuroemergencies trials, the reader will benefit from the authors' perspectives Handbooks, manuals, etc fast Central Nervous System Diseases / drug therapy Neuroprotective Agents / therapeutic use Clinical Trials / methods Emergency Medicine / methods Neuropharmacology / methods Système nerveux / Maladies / Guides, manuels, etc Neuropharmacologie / Guides, manuels, etc Études cliniques / Guides, manuels, etc Clinical trials fast Nervous system / Diseases fast Neuropharmacology fast HEALTH & FITNESS / Diseases / Nervous System (incl. Brain) bisacsh MEDICAL / Neurology bisacsh Medizin Nervous system Diseases Handbooks, manuals, etc Neuropharmacology Handbooks, manuals, etc Clinical trials Handbooks, manuals, etc Nervensystem (DE-588)4041643-4 gnd rswk-swf Notfallmedizin (DE-588)4042676-2 gnd rswk-swf Neuropharmakologie (DE-588)4041896-0 gnd rswk-swf Krankheit (DE-588)4032844-2 gnd rswk-swf Klinisches Experiment (DE-588)4164223-5 gnd rswk-swf Nervensystem (DE-588)4041643-4 s Krankheit (DE-588)4032844-2 s 1\p DE-604 Neuropharmakologie (DE-588)4041896-0 s 2\p DE-604 Klinisches Experiment (DE-588)4164223-5 s 3\p DE-604 Notfallmedizin (DE-588)4042676-2 s 4\p DE-604 Alves, Wayne M. Sonstige oth Skolnick, Brett Evan Sonstige oth http://www.sciencedirect.com/science/book/9780126480825 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 4\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Handbook of neuroemergency clinical trials Handbooks, manuals, etc fast Central Nervous System Diseases / drug therapy Neuroprotective Agents / therapeutic use Clinical Trials / methods Emergency Medicine / methods Neuropharmacology / methods Système nerveux / Maladies / Guides, manuels, etc Neuropharmacologie / Guides, manuels, etc Études cliniques / Guides, manuels, etc Clinical trials fast Nervous system / Diseases fast Neuropharmacology fast HEALTH & FITNESS / Diseases / Nervous System (incl. Brain) bisacsh MEDICAL / Neurology bisacsh Medizin Nervous system Diseases Handbooks, manuals, etc Neuropharmacology Handbooks, manuals, etc Clinical trials Handbooks, manuals, etc Nervensystem (DE-588)4041643-4 gnd Notfallmedizin (DE-588)4042676-2 gnd Neuropharmakologie (DE-588)4041896-0 gnd Krankheit (DE-588)4032844-2 gnd Klinisches Experiment (DE-588)4164223-5 gnd |
| subject_GND | (DE-588)4041643-4 (DE-588)4042676-2 (DE-588)4041896-0 (DE-588)4032844-2 (DE-588)4164223-5 |
| title | Handbook of neuroemergency clinical trials |
| title_auth | Handbook of neuroemergency clinical trials |
| title_exact_search | Handbook of neuroemergency clinical trials |
| title_full | Handbook of neuroemergency clinical trials edited by Wayne M. Alves, Brett E. Skolnick |
| title_fullStr | Handbook of neuroemergency clinical trials edited by Wayne M. Alves, Brett E. Skolnick |
| title_full_unstemmed | Handbook of neuroemergency clinical trials edited by Wayne M. Alves, Brett E. Skolnick |
| title_short | Handbook of neuroemergency clinical trials |
| title_sort | handbook of neuroemergency clinical trials |
| topic | Handbooks, manuals, etc fast Central Nervous System Diseases / drug therapy Neuroprotective Agents / therapeutic use Clinical Trials / methods Emergency Medicine / methods Neuropharmacology / methods Système nerveux / Maladies / Guides, manuels, etc Neuropharmacologie / Guides, manuels, etc Études cliniques / Guides, manuels, etc Clinical trials fast Nervous system / Diseases fast Neuropharmacology fast HEALTH & FITNESS / Diseases / Nervous System (incl. Brain) bisacsh MEDICAL / Neurology bisacsh Medizin Nervous system Diseases Handbooks, manuals, etc Neuropharmacology Handbooks, manuals, etc Clinical trials Handbooks, manuals, etc Nervensystem (DE-588)4041643-4 gnd Notfallmedizin (DE-588)4042676-2 gnd Neuropharmakologie (DE-588)4041896-0 gnd Krankheit (DE-588)4032844-2 gnd Klinisches Experiment (DE-588)4164223-5 gnd |
| topic_facet | Handbooks, manuals, etc Central Nervous System Diseases / drug therapy Neuroprotective Agents / therapeutic use Clinical Trials / methods Emergency Medicine / methods Neuropharmacology / methods Système nerveux / Maladies / Guides, manuels, etc Neuropharmacologie / Guides, manuels, etc Études cliniques / Guides, manuels, etc Clinical trials Nervous system / Diseases Neuropharmacology HEALTH & FITNESS / Diseases / Nervous System (incl. Brain) MEDICAL / Neurology Medizin Nervous system Diseases Handbooks, manuals, etc Neuropharmacology Handbooks, manuals, etc Clinical trials Handbooks, manuals, etc Nervensystem Notfallmedizin Neuropharmakologie Krankheit Klinisches Experiment |
| url | http://www.sciencedirect.com/science/book/9780126480825 |
| work_keys_str_mv | AT alveswaynem handbookofneuroemergencyclinicaltrials AT skolnickbrettevan handbookofneuroemergencyclinicaltrials |