Adenosine receptors and Parkinson's disease:
Gespeichert in:
Bibliographische Detailangaben
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: San Diego, CA Academic Press c2000
Schriftenreihe:Pure and applied mathematics (Academic Press) 60
Schlagworte:
Online-Zugang:Volltext
Beschreibung:This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease. Key Features * Discusses the discovery and development of a novel non-dopaminomimetic agent for Parkinson's disease * Provides the first definitive overview of adenosine antagonists and their role in the treatment of Parkinson's disease * Presents a new mechanism of action of adenosine A2A receptor antagonists in motor function Proposes a hypothesis of adenosine A2A receptor function in the striatum * Comprehensive overview of adenosine, its receptor subtypes, their antagonists/agonists from biochemistry, molecular biology, medicinal chemistry, physiology, pharmacology, and neurochemistry viewpoints
Includes bibliographical references and index
Beschreibung:1 Online-Ressource (xviii, 275 p. [1] col. plate)
ISBN:9780124004054
0124004059
9781435605138
1435605136
0080525954
9780080525952

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