Models of seizures and epilepsy:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Elsevier Academic
©2006
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | An understanding of mechanisms underlying seizure disorders depends critically on the insights provided by model systems. In particular with the development of cellular, molecular, and genetic investigative tools, there has been an explosion of basic epilepsy research. Models of Seizures and Epilepsy brings together, for the first time in 30 years, an overview of the most widely-used models of seizures and epilepsy. Chapters cover a broad range of experimental approaches (from in vitro to whole animal preparations), a variety of epileptiform phenomenology (including burst discharges and seizures), and suggestions for model characterization and validation, such as electrographic, morphologic, pharmacologic, and behavioral features. Experts in the field provide not only technical reviews of these models but also conceptual critiques - commenting on the strengths and limitations of these models, their relationship to clinical phenomenology, and their value in developing a better understanding and treatments. Models of Seizures and Epilepsy is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models for addressing key questions in the field. It also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research. The first comprehensive description of animal models of epilepsy since the early 1970's. Comprehensive analysis of "What the models model" to guide the selection of each model, and what specific questions it will answer. Elegant examples of the use of novel technologies that can be applied in experimental epilepsy research. World expert opinions on the clinical relevance of each model Includes bibliographical references and index |
| Beschreibung: | 1 Online-Ressource (xvii, 687) |
| ISBN: | 9780120885541 0120885549 0080457029 9780080457024 |
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| 500 | |a An understanding of mechanisms underlying seizure disorders depends critically on the insights provided by model systems. In particular with the development of cellular, molecular, and genetic investigative tools, there has been an explosion of basic epilepsy research. Models of Seizures and Epilepsy brings together, for the first time in 30 years, an overview of the most widely-used models of seizures and epilepsy. Chapters cover a broad range of experimental approaches (from in vitro to whole animal preparations), a variety of epileptiform phenomenology (including burst discharges and seizures), and suggestions for model characterization and validation, such as electrographic, morphologic, pharmacologic, and behavioral features. Experts in the field provide not only technical reviews of these models but also conceptual critiques - commenting on the strengths and limitations of these models, their relationship to clinical phenomenology, and their value in developing a better understanding and treatments. Models of Seizures and Epilepsy is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models for addressing key questions in the field. It also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research. The first comprehensive description of animal models of epilepsy since the early 1970's. Comprehensive analysis of "What the models model" to guide the selection of each model, and what specific questions it will answer. Elegant examples of the use of novel technologies that can be applied in experimental epilepsy research. World expert opinions on the clinical relevance of each model | ||
| 500 | |a Includes bibliographical references and index | ||
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| spelling | Models of seizures and epilepsy editors, Asla Pitkänen, Philip A. Schwartzkroin, Solomon L. Moshé Amsterdam Elsevier Academic ©2006 1 Online-Ressource (xvii, 687) txt rdacontent c rdamedia cr rdacarrier An understanding of mechanisms underlying seizure disorders depends critically on the insights provided by model systems. In particular with the development of cellular, molecular, and genetic investigative tools, there has been an explosion of basic epilepsy research. Models of Seizures and Epilepsy brings together, for the first time in 30 years, an overview of the most widely-used models of seizures and epilepsy. Chapters cover a broad range of experimental approaches (from in vitro to whole animal preparations), a variety of epileptiform phenomenology (including burst discharges and seizures), and suggestions for model characterization and validation, such as electrographic, morphologic, pharmacologic, and behavioral features. Experts in the field provide not only technical reviews of these models but also conceptual critiques - commenting on the strengths and limitations of these models, their relationship to clinical phenomenology, and their value in developing a better understanding and treatments. Models of Seizures and Epilepsy is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models for addressing key questions in the field. It also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research. The first comprehensive description of animal models of epilepsy since the early 1970's. Comprehensive analysis of "What the models model" to guide the selection of each model, and what specific questions it will answer. Elegant examples of the use of novel technologies that can be applied in experimental epilepsy research. World expert opinions on the clinical relevance of each model Includes bibliographical references and index PSYCHOLOGY / Neuropsychology bisacsh Epilepsy fast Epilepsy / Animal models fast Spasms fast Epilepsy Spasms Epilepsy Animal models Tiermodell (DE-588)4140660-6 gnd rswk-swf Epilepsie (DE-588)4015035-5 gnd rswk-swf Epileptischer Anfall (DE-588)4296181-6 gnd rswk-swf Epilepsie (DE-588)4015035-5 s Epileptischer Anfall (DE-588)4296181-6 s Tiermodell (DE-588)4140660-6 s 1\p DE-604 Pitkänen, Asla Sonstige oth Schwartzkroin, P. A. Sonstige oth Moshé, Solomon L. Sonstige oth http://www.sciencedirect.com/science/book/9780120885541 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Models of seizures and epilepsy PSYCHOLOGY / Neuropsychology bisacsh Epilepsy fast Epilepsy / Animal models fast Spasms fast Epilepsy Spasms Epilepsy Animal models Tiermodell (DE-588)4140660-6 gnd Epilepsie (DE-588)4015035-5 gnd Epileptischer Anfall (DE-588)4296181-6 gnd |
| subject_GND | (DE-588)4140660-6 (DE-588)4015035-5 (DE-588)4296181-6 |
| title | Models of seizures and epilepsy |
| title_auth | Models of seizures and epilepsy |
| title_exact_search | Models of seizures and epilepsy |
| title_full | Models of seizures and epilepsy editors, Asla Pitkänen, Philip A. Schwartzkroin, Solomon L. Moshé |
| title_fullStr | Models of seizures and epilepsy editors, Asla Pitkänen, Philip A. Schwartzkroin, Solomon L. Moshé |
| title_full_unstemmed | Models of seizures and epilepsy editors, Asla Pitkänen, Philip A. Schwartzkroin, Solomon L. Moshé |
| title_short | Models of seizures and epilepsy |
| title_sort | models of seizures and epilepsy |
| topic | PSYCHOLOGY / Neuropsychology bisacsh Epilepsy fast Epilepsy / Animal models fast Spasms fast Epilepsy Spasms Epilepsy Animal models Tiermodell (DE-588)4140660-6 gnd Epilepsie (DE-588)4015035-5 gnd Epileptischer Anfall (DE-588)4296181-6 gnd |
| topic_facet | PSYCHOLOGY / Neuropsychology Epilepsy Epilepsy / Animal models Spasms Epilepsy Animal models Tiermodell Epilepsie Epileptischer Anfall |
| url | http://www.sciencedirect.com/science/book/9780120885541 |
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