Pathobiology of Alzheimer's disease:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
London
Academic Press
c1995
|
| Schriftenreihe: | Neuroscience perspectives
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | Includes bibliographical references and index Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas. The last decade has seen tremendous advances in our understanding of the pathobiology of Alzheimer's disease. These will lead to the first generation of drugs aimed at prevention rather than cure. This book covers some of the most important and exciting of these advances, with chapters written by many of the leading researchers in the field. With genetic studies as a backbone to this volume many chapters are devoted to the function and regulation of amyloid b-protein precursor (APP) and apolipoprotein E (ApoE). Other chapters describe cell biological approaches helping to piece together the link between the genetic alterations and the phenotype we call Alzheimer's disease. Although APP and its proteolytic cleavage product, amyloid b-protein, do not answer all the questions, detailed research into this system has undoubtedly increased our knowledge of the pathobiology of AD and has lead to the identification of other risk factors. Understanding the role of ApoE in the pathology of Alzheimer's disease promises to open a whole new field in AD research. * * Reviews the current knowledge of the pathogenesis of Alzheimer's Disease from a clinical perspective to a genetic and cell biological perspective * A comprehensive description of the role of amyloid B-protein precursor in Alzheimer's disease. * Up-to-date research data * Clear illustrations complement the text |
| Beschreibung: | 1 Online-Ressource (xiv, 256 p.) |
| ISBN: | 9780122869655 0122869656 9780080538495 0080538495 |
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| series2 | Neuroscience perspectives |
| spelling | Pathobiology of Alzheimer's disease edited by Alison M. Goate and Frank Ashall London Academic Press c1995 1 Online-Ressource (xiv, 256 p.) txt rdacontent c rdamedia cr rdacarrier Neuroscience perspectives Includes bibliographical references and index Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas. The last decade has seen tremendous advances in our understanding of the pathobiology of Alzheimer's disease. These will lead to the first generation of drugs aimed at prevention rather than cure. This book covers some of the most important and exciting of these advances, with chapters written by many of the leading researchers in the field. With genetic studies as a backbone to this volume many chapters are devoted to the function and regulation of amyloid b-protein precursor (APP) and apolipoprotein E (ApoE). Other chapters describe cell biological approaches helping to piece together the link between the genetic alterations and the phenotype we call Alzheimer's disease. Although APP and its proteolytic cleavage product, amyloid b-protein, do not answer all the questions, detailed research into this system has undoubtedly increased our knowledge of the pathobiology of AD and has lead to the identification of other risk factors. Understanding the role of ApoE in the pathology of Alzheimer's disease promises to open a whole new field in AD research. * * Reviews the current knowledge of the pathogenesis of Alzheimer's Disease from a clinical perspective to a genetic and cell biological perspective * A comprehensive description of the role of amyloid B-protein precursor in Alzheimer's disease. * Up-to-date research data * Clear illustrations complement the text Alzheimer's disease HEALTH & FITNESS / Diseases / Alzheimer's & Dementia bisacsh MEDICAL / Neurology bisacsh Ziekte van Alzheimer gtt Pathologische fysiologie gtt Alzheimer's disease fast Alzheimer Disease / pathology Medizin Pathophysiologie (DE-588)4044898-8 gnd rswk-swf Alzheimerkrankheit (DE-588)4112510-1 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Alzheimerkrankheit (DE-588)4112510-1 s Pathophysiologie (DE-588)4044898-8 s 2\p DE-604 Goate, Alison M. Sonstige oth Ashall, Frank Sonstige oth http://www.sciencedirect.com/science/book/9780122869655 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Pathobiology of Alzheimer's disease Alzheimer's disease HEALTH & FITNESS / Diseases / Alzheimer's & Dementia bisacsh MEDICAL / Neurology bisacsh Ziekte van Alzheimer gtt Pathologische fysiologie gtt Alzheimer's disease fast Alzheimer Disease / pathology Medizin Pathophysiologie (DE-588)4044898-8 gnd Alzheimerkrankheit (DE-588)4112510-1 gnd |
| subject_GND | (DE-588)4044898-8 (DE-588)4112510-1 (DE-588)4143413-4 |
| title | Pathobiology of Alzheimer's disease |
| title_auth | Pathobiology of Alzheimer's disease |
| title_exact_search | Pathobiology of Alzheimer's disease |
| title_full | Pathobiology of Alzheimer's disease edited by Alison M. Goate and Frank Ashall |
| title_fullStr | Pathobiology of Alzheimer's disease edited by Alison M. Goate and Frank Ashall |
| title_full_unstemmed | Pathobiology of Alzheimer's disease edited by Alison M. Goate and Frank Ashall |
| title_short | Pathobiology of Alzheimer's disease |
| title_sort | pathobiology of alzheimer s disease |
| topic | Alzheimer's disease HEALTH & FITNESS / Diseases / Alzheimer's & Dementia bisacsh MEDICAL / Neurology bisacsh Ziekte van Alzheimer gtt Pathologische fysiologie gtt Alzheimer's disease fast Alzheimer Disease / pathology Medizin Pathophysiologie (DE-588)4044898-8 gnd Alzheimerkrankheit (DE-588)4112510-1 gnd |
| topic_facet | Alzheimer's disease HEALTH & FITNESS / Diseases / Alzheimer's & Dementia MEDICAL / Neurology Ziekte van Alzheimer Pathologische fysiologie Alzheimer Disease / pathology Medizin Pathophysiologie Alzheimerkrankheit Aufsatzsammlung |
| url | http://www.sciencedirect.com/science/book/9780122869655 |
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