Transmembrane receptors and channels:
Gespeichert in:
Format: | Elektronisch E-Book |
---|---|
Sprache: | English |
Veröffentlicht: |
Greenwich, Conn.
JAI Press
c1996
|
Schriftenreihe: | Biomembranes (Greenwich, Conn.)
v. 6 |
Schlagworte: | |
Online-Zugang: | Volltext |
Beschreibung: | Volume 6 of Biomembranes covers transmembrane receptors and channels. A particularly important role for the membrane is that of passing messages between a cell and its environment. Part I of this volume covers receptors for hormones and growth factors. Here, as in so many other areas of cell biology, the application of the methods of molecular biology have led to the recognition of a number of families of receptors. Typically, such receptors contain an extracellular ligand binding domain, a transmembrane domain, and an intracellular catalytic domain whose activation, as a result of ligand binding, leads to generation of second messengers within the cell and stimulation of a range of cytosolic enzymes. An alternative signaling strategy, exploited in particular in the nervous system, is to use ion channels to allow controlled movement of monovalent (Na<SUP>+</SUP>, K<SUP>+</SUP>) or divalent (Ca<SUP>2+</SUP>) cations in or out of the cell, resulting in changes in membrane potential or alterations in the intracellular concentration of Ca<SUP>2+</SUP>. Part II of this volume is concerned with these ion channels and with other, often simpler, ion channel systems whose study can throw light on channel mechanism Includes bibliographical references and index |
Beschreibung: | 1 Online-Ressource (xii, 420 p.) |
ISBN: | 9781559386630 1559386630 9780080543154 0080543154 |
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500 | |a Volume 6 of Biomembranes covers transmembrane receptors and channels. A particularly important role for the membrane is that of passing messages between a cell and its environment. Part I of this volume covers receptors for hormones and growth factors. Here, as in so many other areas of cell biology, the application of the methods of molecular biology have led to the recognition of a number of families of receptors. Typically, such receptors contain an extracellular ligand binding domain, a transmembrane domain, and an intracellular catalytic domain whose activation, as a result of ligand binding, leads to generation of second messengers within the cell and stimulation of a range of cytosolic enzymes. An alternative signaling strategy, exploited in particular in the nervous system, is to use ion channels to allow controlled movement of monovalent (Na<SUP>+</SUP>, K<SUP>+</SUP>) or divalent (Ca<SUP>2+</SUP>) cations in or out of the cell, resulting in changes in membrane potential or alterations in the intracellular concentration of Ca<SUP>2+</SUP>. Part II of this volume is concerned with these ion channels and with other, often simpler, ion channel systems whose study can throw light on channel mechanism | ||
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dewey-hundreds | 500 - Natural sciences and mathematics |
dewey-ones | 572 - Biochemistry |
dewey-raw | 572/.69 |
dewey-search | 572/.69 |
dewey-sort | 3572 269 |
dewey-tens | 570 - Biology |
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id | DE-604.BV042305541 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T01:17:52Z |
institution | BVB |
isbn | 9781559386630 1559386630 9780080543154 0080543154 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027742533 |
oclc_num | 162596952 |
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owner | DE-1046 |
owner_facet | DE-1046 |
physical | 1 Online-Ressource (xii, 420 p.) |
psigel | ZDB-33-ESD ZDB-33-EBS FAW_PDA_ESD FLA_PDA_ESD |
publishDate | 1996 |
publishDateSearch | 1996 |
publishDateSort | 1996 |
publisher | JAI Press |
record_format | marc |
series2 | Biomembranes (Greenwich, Conn.) |
spelling | Transmembrane receptors and channels editor, A.G. Lee Greenwich, Conn. JAI Press c1996 1 Online-Ressource (xii, 420 p.) txt rdacontent c rdamedia cr rdacarrier Biomembranes (Greenwich, Conn.) v. 6 Volume 6 of Biomembranes covers transmembrane receptors and channels. A particularly important role for the membrane is that of passing messages between a cell and its environment. Part I of this volume covers receptors for hormones and growth factors. Here, as in so many other areas of cell biology, the application of the methods of molecular biology have led to the recognition of a number of families of receptors. Typically, such receptors contain an extracellular ligand binding domain, a transmembrane domain, and an intracellular catalytic domain whose activation, as a result of ligand binding, leads to generation of second messengers within the cell and stimulation of a range of cytosolic enzymes. An alternative signaling strategy, exploited in particular in the nervous system, is to use ion channels to allow controlled movement of monovalent (Na<SUP>+</SUP>, K<SUP>+</SUP>) or divalent (Ca<SUP>2+</SUP>) cations in or out of the cell, resulting in changes in membrane potential or alterations in the intracellular concentration of Ca<SUP>2+</SUP>. Part II of this volume is concerned with these ion channels and with other, often simpler, ion channel systems whose study can throw light on channel mechanism Includes bibliographical references and index SCIENCE / Life Sciences / Biochemistry bisacsh Cell receptors fast Ion channels fast Cell receptors Ion channels Lee, A. G. Sonstige oth http://www.sciencedirect.com/science/book/9781559386630 Verlag Volltext |
spellingShingle | Transmembrane receptors and channels SCIENCE / Life Sciences / Biochemistry bisacsh Cell receptors fast Ion channels fast Cell receptors Ion channels |
title | Transmembrane receptors and channels |
title_auth | Transmembrane receptors and channels |
title_exact_search | Transmembrane receptors and channels |
title_full | Transmembrane receptors and channels editor, A.G. Lee |
title_fullStr | Transmembrane receptors and channels editor, A.G. Lee |
title_full_unstemmed | Transmembrane receptors and channels editor, A.G. Lee |
title_short | Transmembrane receptors and channels |
title_sort | transmembrane receptors and channels |
topic | SCIENCE / Life Sciences / Biochemistry bisacsh Cell receptors fast Ion channels fast Cell receptors Ion channels |
topic_facet | SCIENCE / Life Sciences / Biochemistry Cell receptors Ion channels |
url | http://www.sciencedirect.com/science/book/9781559386630 |
work_keys_str_mv | AT leeag transmembranereceptorsandchannels |