Ex vivo cell therapy:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
San Diego
Academic Press
c1999
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | Over the last two decades advances in the understanding of disease at a cellular and molecular level has led to innovative therapies that are based on the administration of cells which have been modified outside of the body. Ex vivo cell therapy is in essence gene therapy delivered by transfer of therapeutic genes to cells in culture, which are then given to the patient to treat fatal infections such as AIDS, or other conditions such as cancer or genetic diseases. These manipulations include the purification and culture of therapeutic cell subtypes, as well as elimination of cells which cause disease (cancer cells or immune cells reacting to the body itself). Gene therapy can be delivered by transfer of therapeutic genes to cells in culture, which are then given to the patient to treat fatal infections such as AIDS, cancer or genetic diseases. For small-scale laboratory methods to become clinically applicable processes, these new therapies require efficient technologies for cell separation, cell production in culture and gene transfer. This book integrates the recent advances in biological and clinical research with developments in cell-based technologies to provide a comprehensive review for clinicians, researchers, biotechnologists and biomedical engineers working in this rapidly developing area. The biotechnology and pharmaceutical industry requires a broad perspective for development of future technologies, and this text will provide then with an excellent overview of this rapidly evolving field. Key Features * Comprehensive review by leading researchers * Hematopoietic stem cell development: transcriptional control, signaling pathways, hematopoietic growth factors and adhesion molecules * Clinical developments: hematopoietic stem cell transplantation, cellular immunotherapy and gene therapy * Enabling technologies: cell separation, bioreactors, and gene transfer regulatory issues Includes bibliographical references and index |
| Beschreibung: | 1 Online-Ressource (xix, 356 p.) |
| ISBN: | 9780126249606 0126249601 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV042305374 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 150129s1999 |||| o||u| ||||||eng d | ||
| 020 | |a 9780126249606 |9 978-0-12-624960-6 | ||
| 020 | |a 0126249601 |9 0-12-624960-1 | ||
| 035 | |a (OCoLC)162129210 | ||
| 035 | |a (DE-599)BVBBV042305374 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-1046 | ||
| 082 | 0 | |a 615.5 |2 22 | |
| 245 | 1 | 0 | |a Ex vivo cell therapy |c edited Klaus Schindhelm, Robert Nordon |
| 264 | 1 | |a San Diego |b Academic Press |c c1999 | |
| 300 | |a 1 Online-Ressource (xix, 356 p.) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 500 | |a Over the last two decades advances in the understanding of disease at a cellular and molecular level has led to innovative therapies that are based on the administration of cells which have been modified outside of the body. Ex vivo cell therapy is in essence gene therapy delivered by transfer of therapeutic genes to cells in culture, which are then given to the patient to treat fatal infections such as AIDS, or other conditions such as cancer or genetic diseases. These manipulations include the purification and culture of therapeutic cell subtypes, as well as elimination of cells which cause disease (cancer cells or immune cells reacting to the body itself). Gene therapy can be delivered by transfer of therapeutic genes to cells in culture, which are then given to the patient to treat fatal infections such as AIDS, cancer or genetic diseases. For small-scale laboratory methods to become clinically applicable processes, these new therapies require efficient technologies for cell separation, cell production in culture and gene transfer. This book integrates the recent advances in biological and clinical research with developments in cell-based technologies to provide a comprehensive review for clinicians, researchers, biotechnologists and biomedical engineers working in this rapidly developing area. The biotechnology and pharmaceutical industry requires a broad perspective for development of future technologies, and this text will provide then with an excellent overview of this rapidly evolving field. Key Features * Comprehensive review by leading researchers * Hematopoietic stem cell development: transcriptional control, signaling pathways, hematopoietic growth factors and adhesion molecules * Clinical developments: hematopoietic stem cell transplantation, cellular immunotherapy and gene therapy * Enabling technologies: cell separation, bioreactors, and gene transfer regulatory issues | ||
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Gene therapy | |
| 650 | 4 | |a Immunotherapy | |
| 650 | 2 | |a Histothérapie | |
| 650 | 2 | |a Thérapie génique | |
| 650 | 2 | |a Greffe de cellules souches hématopoïétiques | |
| 650 | 7 | |a Cellular therapy |2 fast | |
| 650 | 7 | |a Hematopoietic stem cells / Transplantation |2 fast | |
| 650 | 4 | |a Hematopoietic Stem Cell Transplantation | |
| 650 | 4 | |a Cellular therapy | |
| 650 | 4 | |a Hematopoietic stem cells |x Transplantation | |
| 700 | 1 | |a Schindhelm, Klaus |e Sonstige |4 oth | |
| 700 | 1 | |a Nordon, Robert |e Sonstige |4 oth | |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/book/9780126249606 |x Verlag |3 Volltext |
| 912 | |a ZDB-33-ESD |a ZDB-33-EBS | ||
| 940 | 1 | |q FAW_PDA_ESD | |
| 940 | 1 | |q FLA_PDA_ESD | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-027742366 | ||
Datensatz im Suchindex
| _version_ | 1804152888390320128 |
|---|---|
| any_adam_object | |
| building | Verbundindex |
| bvnumber | BV042305374 |
| collection | ZDB-33-ESD ZDB-33-EBS |
| ctrlnum | (OCoLC)162129210 (DE-599)BVBBV042305374 |
| dewey-full | 615.5 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.5 |
| dewey-search | 615.5 |
| dewey-sort | 3615.5 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03479nmm a2200481zc 4500</leader><controlfield tag="001">BV042305374</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">150129s1999 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780126249606</subfield><subfield code="9">978-0-12-624960-6</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0126249601</subfield><subfield code="9">0-12-624960-1</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)162129210</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV042305374</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-1046</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615.5</subfield><subfield code="2">22</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Ex vivo cell therapy</subfield><subfield code="c">edited Klaus Schindhelm, Robert Nordon</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">San Diego</subfield><subfield code="b">Academic Press</subfield><subfield code="c">c1999</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (xix, 356 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Over the last two decades advances in the understanding of disease at a cellular and molecular level has led to innovative therapies that are based on the administration of cells which have been modified outside of the body. Ex vivo cell therapy is in essence gene therapy delivered by transfer of therapeutic genes to cells in culture, which are then given to the patient to treat fatal infections such as AIDS, or other conditions such as cancer or genetic diseases. These manipulations include the purification and culture of therapeutic cell subtypes, as well as elimination of cells which cause disease (cancer cells or immune cells reacting to the body itself). Gene therapy can be delivered by transfer of therapeutic genes to cells in culture, which are then given to the patient to treat fatal infections such as AIDS, cancer or genetic diseases. For small-scale laboratory methods to become clinically applicable processes, these new therapies require efficient technologies for cell separation, cell production in culture and gene transfer. This book integrates the recent advances in biological and clinical research with developments in cell-based technologies to provide a comprehensive review for clinicians, researchers, biotechnologists and biomedical engineers working in this rapidly developing area. The biotechnology and pharmaceutical industry requires a broad perspective for development of future technologies, and this text will provide then with an excellent overview of this rapidly evolving field. Key Features * Comprehensive review by leading researchers * Hematopoietic stem cell development: transcriptional control, signaling pathways, hematopoietic growth factors and adhesion molecules * Clinical developments: hematopoietic stem cell transplantation, cellular immunotherapy and gene therapy * Enabling technologies: cell separation, bioreactors, and gene transfer regulatory issues</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Gene therapy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Immunotherapy</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">Histothérapie</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">Thérapie génique</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">Greffe de cellules souches hématopoïétiques</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Cellular therapy</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Hematopoietic stem cells / Transplantation</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hematopoietic Stem Cell Transplantation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cellular therapy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hematopoietic stem cells</subfield><subfield code="x">Transplantation</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schindhelm, Klaus</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nordon, Robert</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.sciencedirect.com/science/book/9780126249606</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-33-ESD</subfield><subfield code="a">ZDB-33-EBS</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">FAW_PDA_ESD</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">FLA_PDA_ESD</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-027742366</subfield></datafield></record></collection> |
| id | DE-604.BV042305374 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:17:52Z |
| institution | BVB |
| isbn | 9780126249606 0126249601 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027742366 |
| oclc_num | 162129210 |
| open_access_boolean | |
| owner | DE-1046 |
| owner_facet | DE-1046 |
| physical | 1 Online-Ressource (xix, 356 p.) |
| psigel | ZDB-33-ESD ZDB-33-EBS FAW_PDA_ESD FLA_PDA_ESD |
| publishDate | 1999 |
| publishDateSearch | 1999 |
| publishDateSort | 1999 |
| publisher | Academic Press |
| record_format | marc |
| spelling | Ex vivo cell therapy edited Klaus Schindhelm, Robert Nordon San Diego Academic Press c1999 1 Online-Ressource (xix, 356 p.) txt rdacontent c rdamedia cr rdacarrier Over the last two decades advances in the understanding of disease at a cellular and molecular level has led to innovative therapies that are based on the administration of cells which have been modified outside of the body. Ex vivo cell therapy is in essence gene therapy delivered by transfer of therapeutic genes to cells in culture, which are then given to the patient to treat fatal infections such as AIDS, or other conditions such as cancer or genetic diseases. These manipulations include the purification and culture of therapeutic cell subtypes, as well as elimination of cells which cause disease (cancer cells or immune cells reacting to the body itself). Gene therapy can be delivered by transfer of therapeutic genes to cells in culture, which are then given to the patient to treat fatal infections such as AIDS, cancer or genetic diseases. For small-scale laboratory methods to become clinically applicable processes, these new therapies require efficient technologies for cell separation, cell production in culture and gene transfer. This book integrates the recent advances in biological and clinical research with developments in cell-based technologies to provide a comprehensive review for clinicians, researchers, biotechnologists and biomedical engineers working in this rapidly developing area. The biotechnology and pharmaceutical industry requires a broad perspective for development of future technologies, and this text will provide then with an excellent overview of this rapidly evolving field. Key Features * Comprehensive review by leading researchers * Hematopoietic stem cell development: transcriptional control, signaling pathways, hematopoietic growth factors and adhesion molecules * Clinical developments: hematopoietic stem cell transplantation, cellular immunotherapy and gene therapy * Enabling technologies: cell separation, bioreactors, and gene transfer regulatory issues Includes bibliographical references and index Gene therapy Immunotherapy Histothérapie Thérapie génique Greffe de cellules souches hématopoïétiques Cellular therapy fast Hematopoietic stem cells / Transplantation fast Hematopoietic Stem Cell Transplantation Cellular therapy Hematopoietic stem cells Transplantation Schindhelm, Klaus Sonstige oth Nordon, Robert Sonstige oth http://www.sciencedirect.com/science/book/9780126249606 Verlag Volltext |
| spellingShingle | Ex vivo cell therapy Gene therapy Immunotherapy Histothérapie Thérapie génique Greffe de cellules souches hématopoïétiques Cellular therapy fast Hematopoietic stem cells / Transplantation fast Hematopoietic Stem Cell Transplantation Cellular therapy Hematopoietic stem cells Transplantation |
| title | Ex vivo cell therapy |
| title_auth | Ex vivo cell therapy |
| title_exact_search | Ex vivo cell therapy |
| title_full | Ex vivo cell therapy edited Klaus Schindhelm, Robert Nordon |
| title_fullStr | Ex vivo cell therapy edited Klaus Schindhelm, Robert Nordon |
| title_full_unstemmed | Ex vivo cell therapy edited Klaus Schindhelm, Robert Nordon |
| title_short | Ex vivo cell therapy |
| title_sort | ex vivo cell therapy |
| topic | Gene therapy Immunotherapy Histothérapie Thérapie génique Greffe de cellules souches hématopoïétiques Cellular therapy fast Hematopoietic stem cells / Transplantation fast Hematopoietic Stem Cell Transplantation Cellular therapy Hematopoietic stem cells Transplantation |
| topic_facet | Gene therapy Immunotherapy Histothérapie Thérapie génique Greffe de cellules souches hématopoïétiques Cellular therapy Hematopoietic stem cells / Transplantation Hematopoietic Stem Cell Transplantation Hematopoietic stem cells Transplantation |
| url | http://www.sciencedirect.com/science/book/9780126249606 |
| work_keys_str_mv | AT schindhelmklaus exvivocelltherapy AT nordonrobert exvivocelltherapy |