Metabolic engineering: principles and methodologies
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
San Diego
Academic Press
1998
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes. Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems. Key Features * Demonstrates metabolic engineering in action with numerous examples of pathway modification * Includes methods for identifying key enzymes in metabolic networks * Contains a comprehensive review of metabolic biochemistry * Discusses metabolic regulation at the gene, enzyme, operon, and cell levels * Explains concepts of stoichiometry, kinetics, and thermodynamics of metabolic pathways * Minimizes mathematical complexity * Links to a Web page to communicate updates of the software code and homework problems Includes bibliographical references and index |
| Beschreibung: | 1 Online-Ressource (xxi, 725 pages) |
| ISBN: | 9780126662603 0126662606 9780080536286 008053628X |
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| 500 | |a Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes. Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems. Key Features * Demonstrates metabolic engineering in action with numerous examples of pathway modification * Includes methods for identifying key enzymes in metabolic networks * Contains a comprehensive review of metabolic biochemistry * Discusses metabolic regulation at the gene, enzyme, operon, and cell levels * Explains concepts of stoichiometry, kinetics, and thermodynamics of metabolic pathways * Minimizes mathematical complexity * Links to a Web page to communicate updates of the software code and homework problems | ||
| 500 | |a Includes bibliographical references and index | ||
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Datensatz im Suchindex
| _version_ | 1804152888330551296 |
|---|---|
| any_adam_object | |
| author | Stephanopoulos, G. |
| author_facet | Stephanopoulos, G. |
| author_role | aut |
| author_sort | Stephanopoulos, G. |
| author_variant | g s gs |
| building | Verbundindex |
| bvnumber | BV042305344 |
| collection | ZDB-33-ESD ZDB-33-EBS |
| ctrlnum | (OCoLC)162128826 (DE-599)BVBBV042305344 |
| dewey-full | 660.6/3 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 660 - Chemical engineering |
| dewey-raw | 660.6/3 |
| dewey-search | 660.6/3 |
| dewey-sort | 3660.6 13 |
| dewey-tens | 660 - Chemical engineering |
| discipline | Chemie / Pharmazie |
| format | Electronic eBook |
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| id | DE-604.BV042305344 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:17:52Z |
| institution | BVB |
| isbn | 9780126662603 0126662606 9780080536286 008053628X |
| language | English |
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| physical | 1 Online-Ressource (xxi, 725 pages) |
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| spelling | Stephanopoulos, G. Verfasser aut Metabolic engineering principles and methodologies Gregory N. Stephanopoulos, Aristos A. Aristidou, Jens Nielsen San Diego Academic Press 1998 1 Online-Ressource (xxi, 725 pages) txt rdacontent c rdamedia cr rdacarrier Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes. Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems. Key Features * Demonstrates metabolic engineering in action with numerous examples of pathway modification * Includes methods for identifying key enzymes in metabolic networks * Contains a comprehensive review of metabolic biochemistry * Discusses metabolic regulation at the gene, enzyme, operon, and cell levels * Explains concepts of stoichiometry, kinetics, and thermodynamics of metabolic pathways * Minimizes mathematical complexity * Links to a Web page to communicate updates of the software code and homework problems Includes bibliographical references and index Metabolism Biochemistry Metabolieten gtt Moleculaire genetica gtt Celbiologie gtt Biosynthese gtt Metabolismo larpcal Bioquimica larpcal Engenharia quimica larpcal SCIENCE / Biotechnology bisacsh Biochemical engineering fast Metabolism fast Biochemical engineering Stoffwechsel (DE-588)4057699-1 gnd rswk-swf Methode (DE-588)4038971-6 gnd rswk-swf Biotechnologie (DE-588)4069491-4 gnd rswk-swf Industrielle Mikrobiologie (DE-588)4026845-7 gnd rswk-swf Industrielle Mikrobiologie (DE-588)4026845-7 s Stoffwechsel (DE-588)4057699-1 s Biotechnologie (DE-588)4069491-4 s Methode (DE-588)4038971-6 s 1\p DE-604 Aristidou, Aristos A. Sonstige oth Nielsen, Jens Høiriis Sonstige oth http://www.sciencedirect.com/science/book/9780126662603 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Stephanopoulos, G. Metabolic engineering principles and methodologies Metabolism Biochemistry Metabolieten gtt Moleculaire genetica gtt Celbiologie gtt Biosynthese gtt Metabolismo larpcal Bioquimica larpcal Engenharia quimica larpcal SCIENCE / Biotechnology bisacsh Biochemical engineering fast Metabolism fast Biochemical engineering Stoffwechsel (DE-588)4057699-1 gnd Methode (DE-588)4038971-6 gnd Biotechnologie (DE-588)4069491-4 gnd Industrielle Mikrobiologie (DE-588)4026845-7 gnd |
| subject_GND | (DE-588)4057699-1 (DE-588)4038971-6 (DE-588)4069491-4 (DE-588)4026845-7 |
| title | Metabolic engineering principles and methodologies |
| title_auth | Metabolic engineering principles and methodologies |
| title_exact_search | Metabolic engineering principles and methodologies |
| title_full | Metabolic engineering principles and methodologies Gregory N. Stephanopoulos, Aristos A. Aristidou, Jens Nielsen |
| title_fullStr | Metabolic engineering principles and methodologies Gregory N. Stephanopoulos, Aristos A. Aristidou, Jens Nielsen |
| title_full_unstemmed | Metabolic engineering principles and methodologies Gregory N. Stephanopoulos, Aristos A. Aristidou, Jens Nielsen |
| title_short | Metabolic engineering |
| title_sort | metabolic engineering principles and methodologies |
| title_sub | principles and methodologies |
| topic | Metabolism Biochemistry Metabolieten gtt Moleculaire genetica gtt Celbiologie gtt Biosynthese gtt Metabolismo larpcal Bioquimica larpcal Engenharia quimica larpcal SCIENCE / Biotechnology bisacsh Biochemical engineering fast Metabolism fast Biochemical engineering Stoffwechsel (DE-588)4057699-1 gnd Methode (DE-588)4038971-6 gnd Biotechnologie (DE-588)4069491-4 gnd Industrielle Mikrobiologie (DE-588)4026845-7 gnd |
| topic_facet | Metabolism Biochemistry Metabolieten Moleculaire genetica Celbiologie Biosynthese Metabolismo Bioquimica Engenharia quimica SCIENCE / Biotechnology Biochemical engineering Stoffwechsel Methode Biotechnologie Industrielle Mikrobiologie |
| url | http://www.sciencedirect.com/science/book/9780126662603 |
| work_keys_str_mv | AT stephanopoulosg metabolicengineeringprinciplesandmethodologies AT aristidouaristosa metabolicengineeringprinciplesandmethodologies AT nielsenjenshøiriis metabolicengineeringprinciplesandmethodologies |