Recent advances in prolactin research:
Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors. The chapters are written by experts in these fields and focus on identifying and r...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cham [u.a.]
Springer
2015
|
| Schriftenreihe: | Advances in experimental medicine and biology
846 |
| Zusammenfassung: | Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors. The chapters are written by experts in these fields and focus on identifying and reviewing timely experimental findings that provide new insights into the expanding role of PRL in the pathophysiology associated with a variety of human conditions. Prolactin is a peptide hormone that is best known for its role in lactation. Prolactin also has an influence on hematopoiesis and angiogenesis, and is involved in the regulation of blood clotting through several pathways. Although PRL was discovered more than 80 years ago, the understanding of PRL signaling and its relationship to various pathologies is still very incomplete. PRL is not only a pituitary hormone with an important role in reproduction, but PRL also acts as a cytokine, modulating a wide variety of physiological processes. For example, data gathered during the last decade have demonstrated that locally produced PRL acts as the autocrine/paracrine factor and plays a contributory role during breast oncogenesis. In fact, the scientific and clinical communities have suggested that the manipulation of the PRL axis may lead to the successful treatment of breast cancer. However, recent work has demonstrated that the role of the PRL axis is much more complex than first envisaged |
| Beschreibung: | VIII, 282 S. Ill., graph. Darst. |
| ISBN: | 9783319121130 |
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| 490 | 1 | |a Advances in experimental medicine and biology |v 846 | |
| 520 | 1 | |a Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors. The chapters are written by experts in these fields and focus on identifying and reviewing timely experimental findings that provide new insights into the expanding role of PRL in the pathophysiology associated with a variety of human conditions. Prolactin is a peptide hormone that is best known for its role in lactation. Prolactin also has an influence on hematopoiesis and angiogenesis, and is involved in the regulation of blood clotting through several pathways. Although PRL was discovered more than 80 years ago, the understanding of PRL signaling and its relationship to various pathologies is still very incomplete. PRL is not only a pituitary hormone with an important role in reproduction, but PRL also acts as a cytokine, modulating a wide variety of physiological processes. For example, data gathered during the last decade have demonstrated that locally produced PRL acts as the autocrine/paracrine factor and plays a contributory role during breast oncogenesis. In fact, the scientific and clinical communities have suggested that the manipulation of the PRL axis may lead to the successful treatment of breast cancer. However, recent work has demonstrated that the role of the PRL axis is much more complex than first envisaged | |
| 830 | 0 | |a Advances in experimental medicine and biology |v 846 |w (DE-604)BV000003102 |9 846 | |
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Datensatz im Suchindex
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| any_adam_object | |
| author | Diakonova, Maria |
| author_GND | (DE-588)1064863868 |
| author_facet | Diakonova, Maria |
| author_role | aut |
| author_sort | Diakonova, Maria |
| author_variant | m d md |
| building | Verbundindex |
| bvnumber | BV042265143 |
| ctrlnum | (OCoLC)900407111 (DE-599)GBV813668352 |
| dewey-full | 612 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612 |
| dewey-search | 612 |
| dewey-sort | 3612 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
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| id | DE-604.BV042265143 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T01:16:47Z |
| institution | BVB |
| isbn | 9783319121130 |
| language | English |
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| physical | VIII, 282 S. Ill., graph. Darst. |
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| publisher | Springer |
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| series | Advances in experimental medicine and biology |
| series2 | Advances in experimental medicine and biology |
| spelling | Diakonova, Maria Verfasser (DE-588)1064863868 aut Recent advances in prolactin research Maria Diakonova, ed. Cham [u.a.] Springer 2015 VIII, 282 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Advances in experimental medicine and biology 846 Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors. The chapters are written by experts in these fields and focus on identifying and reviewing timely experimental findings that provide new insights into the expanding role of PRL in the pathophysiology associated with a variety of human conditions. Prolactin is a peptide hormone that is best known for its role in lactation. Prolactin also has an influence on hematopoiesis and angiogenesis, and is involved in the regulation of blood clotting through several pathways. Although PRL was discovered more than 80 years ago, the understanding of PRL signaling and its relationship to various pathologies is still very incomplete. PRL is not only a pituitary hormone with an important role in reproduction, but PRL also acts as a cytokine, modulating a wide variety of physiological processes. For example, data gathered during the last decade have demonstrated that locally produced PRL acts as the autocrine/paracrine factor and plays a contributory role during breast oncogenesis. In fact, the scientific and clinical communities have suggested that the manipulation of the PRL axis may lead to the successful treatment of breast cancer. However, recent work has demonstrated that the role of the PRL axis is much more complex than first envisaged Advances in experimental medicine and biology 846 (DE-604)BV000003102 846 |
| spellingShingle | Diakonova, Maria Recent advances in prolactin research Advances in experimental medicine and biology |
| title | Recent advances in prolactin research |
| title_auth | Recent advances in prolactin research |
| title_exact_search | Recent advances in prolactin research |
| title_full | Recent advances in prolactin research Maria Diakonova, ed. |
| title_fullStr | Recent advances in prolactin research Maria Diakonova, ed. |
| title_full_unstemmed | Recent advances in prolactin research Maria Diakonova, ed. |
| title_short | Recent advances in prolactin research |
| title_sort | recent advances in prolactin research |
| volume_link | (DE-604)BV000003102 |
| work_keys_str_mv | AT diakonovamaria recentadvancesinprolactinresearch |