Metronomic chemotherapy: pharmacology and clinical applications
This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its a...
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Berlin [u.a.]
Springer
2014
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Zusammenfassung: | This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoenconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic |
| Beschreibung: | XVI, 295 S. Ill., graph. Darst. |
| ISBN: | 3662436035 9783662436035 |
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| 245 | 1 | 0 | |a Metronomic chemotherapy |b pharmacology and clinical applications |c Guido Bocci ; Giulio Francia, ed. |
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| 520 | 1 | |a This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoenconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic | |
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Datensatz im Suchindex
| _version_ | 1804152776452734976 |
|---|---|
| adam_text | Contents
Part I Pharmacological Bases of Metronomic Chemotherapy
1
Development and Evolution of the Concept of Metronomic
Chemotherapy: A Personal Perspective
........................ 3
Robert S.
Kerbel
2
Mechanisms of Action of Low-Dose Metronomic
Chemotherapy
............................................ 23
Ella Fremder
and Yuval
S
hak
ed
3
Effects of Metronomic Chemotherapy on Immunity
............. 39
Marnom Harada
4
Preclinical Activity of Metronomic Regimens with Alkylating
Agents and Antimetabolites
................................. 53
Marta Vavgs, Berta
Laquente, and
Francese
Vmals
5
Metronomic Chemotherapy Regimens Using
Microtubule-Targeting Agents: Mechanisms of Action,
Preclinical Activity and Future Developments
.................. 69
Eddy Pasquier,
Mana Ka vallans,
and Nicolas Andre
Part II Clinical Activity of Metronomic Chemotherapy
6
Metronomic Chemotherapy in Breast Cancers
.................. 93
Elisabetta Munzone,
Francesco Bettolini,
and Marco Colleoni
7
Overview of Metronomic Chemotherapy in SWOG
Breast Cancer Cooperative Group Clinical Trials
...............
Ill
Zeina A. Nahleh
8
Clinical Trials of Low-Dose Metronomic Chemotherapy
in Castration-Resistant Prostate Cancer
....................... 119
Keerno
Delos
Santos, Lavarnan Sivanathan, Kelly Lien,
ала
Urban Ernmenegger
IX
x
Contents
9
The Role of Metronomic Chemotherapy in the Treatment
of Metastatic Colorectal Cancer Patients
....................... 135
Lisa
Salvatore,
Federica
Zoratto, Fotios Loupakis,
and Alfredo Falcone
10
Clinical Activity of Metronomic Chemotherapy
in Central Nervous System Cancers
........................... 143
Doo-Sik Kong and Do-Hyun Nam
11
Metronomic Chemotherapy in
Pediatrie
Malignancies
........... 157
N arges
Balu ch,
Susini
Kumar,
Reza
Mokhtari,
and
Sylvám
В
aru
chel
12
Metronomic Chemotherapy in
Hematologica!
Malignancies
.............................................. 173
Pannee Praditsuktavorn and Jia Ruan
13
Clinical Activity of Metronomic Chemotherapy
in Liver Cancers
........................................... 189
Yu-Yun Shao, Ann
-Lii
Cheng, and Chrh-Hung Hsu
14
Metronomic Chemotherapy in Gynecological Cancers
........... 203
Victoria A. Forte and
Agustín
A. Garcia
15
Metronomic Chemotherapy in Non-Small-Cell
Lung Cancer
.............................................. 217
Athanasios Kotsakis, Nikolaos Kentepozidis,
and Vassilis Geoigoulias
Part
ΠΙ
Clinical Pharmacology of Metronomic Chemotherapy
16
Pharmacokinetics and Pharmacogenetics of Metronomic
Chemotherapy
............................................ 229
Guido Bocci
and
Giulio Francia
17
Metronomics: Potential Social Impact and New Business
Models to Improve Availability of Cancer Treatments
............ 247
Yuliya Snihur, Eddy Pasquier,
Graciela
Scharovsky,
and Nicolas Andre
18
Adverse Side Effects Associated with the Use of Low-Dose
Metronomic Chemotherapy
................................. 263
Keemo
Delos
Santos, Kelly Lien, Soley Georgsdottir,
Lavarnan Sivanathan, and Urban Emmenegger
Contents xi
Part IV Metronomic Chemotherapy in Veterinarian Clinic
19
Clinical Studies of Metronomic Chemotherapy in Dogs
.......... 283
Veronica Marchetta
ала
Mario Giorgi
This book analyzes all aspects of metronom¬
ic chemotherapy, a new approach involving
low-dose, long-term, and frequently admin¬
istered therapy that has
preclinical
and clini¬
cal activity in various tumors. After an open¬
ing section on the pharmacological bases
of metronomic chemotherapy, including its
antiangiogenic effects and impact on immu¬
nity, preclinical studies on various classes of
drug are discussed. Clinical applications of
metronomic chemotherapy in a wide variety
of tumors are then addressed in detail with
description of the results of all published
studies. The
clinicai
pharmacology of metro-
nomic chemotherapy is also considered in
depth, encompassing pharmacokinetics,
pharmacogenctics, pharmacoeconomics,
and adverse drug reactions. The book closes
by describing the role of this therapy in the
veterinarian clinic.
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| ctrlnum | (OCoLC)894766665 (DE-599)BVBBV042238037 |
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| indexdate | 2024-07-10T01:16:05Z |
| institution | BVB |
| isbn | 3662436035 9783662436035 |
| language | English |
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| spelling | Metronomic chemotherapy pharmacology and clinical applications Guido Bocci ; Giulio Francia, ed. Berlin [u.a.] Springer 2014 XVI, 295 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoenconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic Medizin Medicine Oncology Toxicology Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Chemotherapie (DE-588)4127083-6 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Krebs Medizin (DE-588)4073781-0 s Chemotherapie (DE-588)4127083-6 s DE-604 Bocci, Guido Sonstige oth Francia, Giulio Sonstige oth Erscheint auch als Online-Ausgabe 978-3-662-43604-2 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027676223&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027676223&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Metronomic chemotherapy pharmacology and clinical applications Medizin Medicine Oncology Toxicology Krebs Medizin (DE-588)4073781-0 gnd Chemotherapie (DE-588)4127083-6 gnd |
| subject_GND | (DE-588)4073781-0 (DE-588)4127083-6 (DE-588)4143413-4 |
| title | Metronomic chemotherapy pharmacology and clinical applications |
| title_auth | Metronomic chemotherapy pharmacology and clinical applications |
| title_exact_search | Metronomic chemotherapy pharmacology and clinical applications |
| title_full | Metronomic chemotherapy pharmacology and clinical applications Guido Bocci ; Giulio Francia, ed. |
| title_fullStr | Metronomic chemotherapy pharmacology and clinical applications Guido Bocci ; Giulio Francia, ed. |
| title_full_unstemmed | Metronomic chemotherapy pharmacology and clinical applications Guido Bocci ; Giulio Francia, ed. |
| title_short | Metronomic chemotherapy |
| title_sort | metronomic chemotherapy pharmacology and clinical applications |
| title_sub | pharmacology and clinical applications |
| topic | Medizin Medicine Oncology Toxicology Krebs Medizin (DE-588)4073781-0 gnd Chemotherapie (DE-588)4127083-6 gnd |
| topic_facet | Medizin Medicine Oncology Toxicology Krebs Medizin Chemotherapie Aufsatzsammlung |
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