Resistance to Targeted ABC Transporters in Cancer:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Cham [u.a.]
Springer
2015
|
| Schriftenreihe: | Resistance to Targeted Anti-Cancer Therapeutics
4 |
| Schlagworte: | |
| Online-Zugang: | TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9783319098012 |
| DOI: | 10.1007/978-3-319-09801-2 |
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Datensatz im Suchindex
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| adam_text | RESISTANCE TO TARGETED ABC TRANSPORTERS IN CANCER
/
: 2015
TABLE OF CONTENTS / INHALTSVERZEICHNIS
ROLE OF P-GLYCOPROTEIN FOR RESISTANCE OF TUMORS TO ANTICANCER DRUGS:
FROM BENCH TO BEDSIDE
CLINICAL RELEVANCE OF MULTIDRUG-RESISTANCE-RELATED PROTEINS (MRPS) FOR
ANTICANCER DRUG RESISTANCE AND PROGNOSIS
ROLE OF BREAST CANCER RESISTANCE PROTEIN (BCRP, ABCG2) IN CANCER
OUTCOMES AND DRUG RESISTANCE
A NEW STRATEGY OF ALA-PHOTODYNAMIC CANCER THERAPY: INHIBITION OF ABC
TRANSPORTER ABCG2
ABC TRANSPORTERS IN CANCER STEM-LIKE CELLS
RADIOPHARMACEUTICALS FOR THE IMAGING OF ABC-TRANSPORTER-MEDIATED
MULTIDRUG RESISTANCE IN CANCER
MODULATION OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE BY SYNTHETIC
AND PHYTOCHEMICAL SMALL MOLECULES, MONOCLONAL ANTIBODIES AND THERAPEUTIC
NUCLEIC ACIDS
ABC TRANSPORTER MODULATORY DRUGS FROM MARINE SOURCES: A NEW APPROACH TO
OVERCOME DRUG RESISTANCE IN CANCER
THE ROLE OF ABC MULTIDRUG TRANSPORTERS IN RESISTANCE TO TARGETED
ANTI-CANCER KINASE INHIBITORS
NANOTECHNOLOGY TO COMBAT MULTIDRUG RESISTANCE IN CANCER
DRUGS AFFECTING EPIGENETIC MODIFICATIONS OF ABC TRANSPORTERS
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
RESISTANCE TO TARGETED ABC TRANSPORTERS IN CANCER
/
: 2015
ABSTRACT / INHALTSTEXT
THIS VOLUME COVERS THE MOST CURRENT TOPICS RELEVANT TO ABC TRANSPORTERS
AND RESISTANCE TO NOVEL AND ESTABLISHED ANTICANCER DRUGS, PROGNOSIS OF
PATIENTS TO COMPOUNDS TO MODULATE MULTIDRUG RESISTANCE, COMPOUNDS USED
IN PHOTODYNAMIC THERAPY, TYROSINE KINASE INHIBITORS AND OTHERS.
FURTHERMORE, THE POTENTIAL OF RADIOPHARMACEUTICALS FOR DIAGNOSIS OF
MULTIDRUG-RESISTANT TUMORS IS ALSO DISCUSSED. THE DEVELOPMENT OF
RESISTANCE IS A MAJOR OBSTACLE IN CANCER CHEMOTHERAPY SINCE DECADES.
DRUG RESISTANCE MAY DEVELOP DURING REPEATED TREATMENT CYCLES AFTER
INITIALLY SUCCESSFUL THERAPY (ACQUIRED OR SECONDARY RESISTANCE).
ALTERNATIVELY, TUMORS MAY BE RESISTANT FROM THE BEGINNING (INHERENT OR
PRIMARY RESISTANCE). THE FAILURE OF CHEMOTHERAPY IS A MAJOR REASON FOR
THE FATAL OUTCOME OF TUMOR DISEASES IN MANY PATIENTS. EVEN WORSE, TUMORS
FREQUENTLY DEVELOP NOT ONLY RESISTANCE TO SINGLE DRUGS, BUT ALSO TO MANY
OTHERS AT THE SAME TIME. THIS PHENOMENON WAS TERMED MULTIDRUG RESISTANCE
AND DECREASES THE SUCCESS RATES OF THERAPY REGIMENS WITH COMBINATIONS OF
STRUCTURALLY AND FUNCTIONALLY DIFFERENT DRUGS. THE UNCOMMONLY BROAD
SPECTRUM OF ANTICANCER AGENTS THAT ARE TRANSPORTED BY ABC TRANSPORTERS
MAKES THESE PROTEINS EXQUISITE TARGETS TO SEARCH FOR COMPOUNDS THAT
INHIBIT THEIR TRANSPORT FUNCTION. A HUGE AMOUNT OF COMPOUNDS FROM MANY
PHARMACOLOGICALLY ESTABLISHED DRUG WERE OBSERVED TO INHIBIT ABC
TRANSPORTERS AND TO REVERSE MULTIDRUG RESISTANCE—ALL OF THESE TOPICS
AND MORE IS EXPLORED IN THIS VOLUME
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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| series | Resistance to Targeted Anti-Cancer Therapeutics |
| series2 | Resistance to Targeted Anti-Cancer Therapeutics |
| spelling | Resistance to Targeted ABC Transporters in Cancer Thomas Efferth, ed. Cham [u.a.] Springer 2015 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Resistance to Targeted Anti-Cancer Therapeutics 4 Medizin Medicine Oncology Drug interactions Biomedicine Efferth, Thomas 1960- Sonstige (DE-588)112533116 oth Erscheint auch als Druckausgabe 978-3-319-09800-5 Resistance to Targeted Anti-Cancer Therapeutics 4 (DE-604)BV041037744 4 https://doi.org/10.1007/978-3-319-09801-2 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027669125&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027669125&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Resistance to Targeted ABC Transporters in Cancer Resistance to Targeted Anti-Cancer Therapeutics Medizin Medicine Oncology Drug interactions Biomedicine |
| title | Resistance to Targeted ABC Transporters in Cancer |
| title_auth | Resistance to Targeted ABC Transporters in Cancer |
| title_exact_search | Resistance to Targeted ABC Transporters in Cancer |
| title_full | Resistance to Targeted ABC Transporters in Cancer Thomas Efferth, ed. |
| title_fullStr | Resistance to Targeted ABC Transporters in Cancer Thomas Efferth, ed. |
| title_full_unstemmed | Resistance to Targeted ABC Transporters in Cancer Thomas Efferth, ed. |
| title_short | Resistance to Targeted ABC Transporters in Cancer |
| title_sort | resistance to targeted abc transporters in cancer |
| topic | Medizin Medicine Oncology Drug interactions Biomedicine |
| topic_facet | Medizin Medicine Oncology Drug interactions Biomedicine |
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