DNA Replication Control in Microbial Cell Factories:
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cham [u.a.]
Springer
2015
|
| Schriftenreihe: | SpringerBriefs in Microbiology
|
| Schlagworte: | |
| Online-Zugang: | TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9783319105338 |
| DOI: | 10.1007/978-3-319-10533-8 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804152763988312064 |
|---|---|
| adam_text | DNA REPLICATION CONTROL IN MICROBIAL CELL FACTORIES
/ GLINKOWSKA, MONIKA
: 2015
TABLE OF CONTENTS / INHALTSVERZEICHNIS
INTRODUCTION.-COORDINATING DUPLICATION OF GENETIC MATERIAL WITH CELL
GROWTH – CURRENT VIEWS AND OLD QUESTIONS.-STRUCTURAL ORGANIZATION OF
CELLULAR PROCESSES AND THE REGULATION OF CELL CYCLE
THE LINK BETWEEN METABOLISM AND DNA REPLICATION
TRANSCRIPTIONAL ACTIVATION – THE UNSOLVED PROBLEM
ACTIVITY OF DNAA IS INHIBITED BY COMPONENTS OF TRANSLATION MACHINERY
NUCLEOID-ASSOCIATED PROTEINS MODULATE ACTIVITY OF THE DNAA INITIATOR
INTERACTION OF DNAA WITH ACIDIC COMPONENTS OF FLUID CELLULAR MEMBRANE
REGULATES ITS NUCLEOTIDE-BOUND STATUS AND BINDING TO ORIC
INFLUENCE OF DNA REPLICATION ON CELL STRUCTURE AND FUNCTION
CONCLUSIONS
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
DNA REPLICATION CONTROL IN MICROBIAL CELL FACTORIES
/ GLINKOWSKA, MONIKA
: 2015
ABSTRACT / INHALTSTEXT
THIS WORK DESCRIBES THE CURRENT KNOWLEDGE OF BIOCHEMICAL MECHANISMS
REGULATING INITIATION OF DNA REPLICATION IN ESCHERICHIA COLI, WHICH
FOCUSES ON THE CONTROL OF ACTIVITY OF THE DNAA PROTEIN. EXAMPLES OF
DIRECT LINKAGES BETWEEN DNA REPLICATION AND OTHER CELLULAR PROCESSES ARE
PROVIDED. IN ADDITION,SIMILARITIES OF THE MECHANISMS OF REGULATION OF
DNA REPLICATION OPERATING IN PROKARYOTIC AND EUKARYOTIC CELLS ARE
IDENTIFIED, ANDIMPLICATIONS FOR UNDERSTANDING MORE COMPLEX PROCESSES,
LIKE CARCINOGENESIS ARE SUGGESTED. STUDIES OF RECENT YEARS PROVIDED
EVIDENCE THAT REGULATION OF DNA REPLICATION IN BACTERIA IS MORE COMPLEX
THAN PREVIOUSLY ANTICIPATED. MULTIPLE LAYERS OF CONTROL SEEM TO ENSURE
COORDINATION OF THIS PROCESS WITH THE INCREASE OF CELLULAR MASS AND THE
DIVISION CYCLE. METABOLIC PROCESSES AND MEMBRANE COMPOSITION MAY SERVE
AS POINTS WHERE INTEGRATION OF GENOME REPLICATION WITH GROWTH CONDITIONS
OCCURS. IT IS ALSO LIKELY THAT COUPLING OF DNA SYNTHESIS WITH CELLULAR
METABOLISM MAY INVOLVE INTERACTIONS OF REPLICATION PROTEINS WITH OTHER
MACROMOLECULAR COMPLEXES, RESPONSIBLE FOR VARIOUS CELLULAR PROCESSES.
THUS, THE EXACT SET OF FACTORS PARTICIPATING IN TRIGGERING THE
REPLICATION INITIATION MAY DIFFER DEPENDING ON GROWTH CONDITIONS.
THEREFORE, UNDERSTANDING THE REGULATION OF DNA DUPLICATION REQUIRES
PLACING THIS PROCESS IN THE CONTEXT OFTHE CURRENT KNOWLEDGE ON
BACTERIAL METABOLISM, AS WELL AS CELLULAR AND CHROMOSOMAL STRUCTURE.
MOREOVER, IN BOTH ESCHERICHIA COLI AND EUKARYOTIC CELLS, REPLICATION
INITIATOR PROTEINS WERE SHOWN TO PLAY OTHER ROLES IN ADDITION TO DRIVING
THE ASSEMBLY OF REPLICATION COMPLEXES, WHICH CONSTITUTES ANOTHER, YET
NOT SUFFICIENTLY UNDERSTOOD, LAYER OF COORDINATING DNA REPLICATION WITH
THE CELL CYCLE
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| author | Glinkowska, Monika Boss, Lidia Węgrzyn, Grzegorz |
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| spelling | Glinkowska, Monika Verfasser (DE-588)1060735326 aut DNA Replication Control in Microbial Cell Factories Monika Glinkowska ; Lidia Boss ; Grzegorz Wegrzyn Cham [u.a.] Springer 2015 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier SpringerBriefs in Microbiology Biowissenschaften Life sciences Microbiology Cytology Life Sciences Boss, Lidia Verfasser (DE-588)1060735377 aut Węgrzyn, Grzegorz Verfasser aut Erscheint auch als Druckausgabe 978-3-319-10532-1 https://doi.org/10.1007/978-3-319-10533-8 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027668696&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027668696&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Glinkowska, Monika Boss, Lidia Węgrzyn, Grzegorz DNA Replication Control in Microbial Cell Factories Biowissenschaften Life sciences Microbiology Cytology Life Sciences |
| title | DNA Replication Control in Microbial Cell Factories |
| title_auth | DNA Replication Control in Microbial Cell Factories |
| title_exact_search | DNA Replication Control in Microbial Cell Factories |
| title_full | DNA Replication Control in Microbial Cell Factories Monika Glinkowska ; Lidia Boss ; Grzegorz Wegrzyn |
| title_fullStr | DNA Replication Control in Microbial Cell Factories Monika Glinkowska ; Lidia Boss ; Grzegorz Wegrzyn |
| title_full_unstemmed | DNA Replication Control in Microbial Cell Factories Monika Glinkowska ; Lidia Boss ; Grzegorz Wegrzyn |
| title_short | DNA Replication Control in Microbial Cell Factories |
| title_sort | dna replication control in microbial cell factories |
| topic | Biowissenschaften Life sciences Microbiology Cytology Life Sciences |
| topic_facet | Biowissenschaften Life sciences Microbiology Cytology Life Sciences |
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