Macrophages: Biology and Role in the Pathology of Diseases:
Gespeichert in:
Format: | Elektronisch E-Book |
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Sprache: | English |
Veröffentlicht: |
New York, NY [u.a.]
Springer
2014
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Schlagworte: | |
Online-Zugang: | TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract |
Beschreibung: | 1 Online-Ressource |
ISBN: | 9781493913114 |
DOI: | 10.1007/978-1-4939-1311-4 |
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Datensatz im Suchindex
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adam_text | MACROPHAGES: BIOLOGY AND ROLE IN THE PATHOLOGY OF DISEASES
/
: 2014
TABLE OF CONTENTS / INHALTSVERZEICHNIS
PART I MACROPHAGE: ORIGIN, ACTIVATION AND POLARIZATION
BLOOD MONOCYTES AND THEIRSUBSETS IN HEALTH AND DISEASE
POLARIZED ACTIVATION OF MACROPHAGES
ALTERNATIVE ACTIVATION OF MACROPHAGES: CONCEPTS AND PROSPECTS
REGULATORY MACROPHAGES AND THE MAINTENANCE OF HOMEOSTASIS
PART II MACROPHAGES AND THEIR DIVERSE FUNCTIONS
PHAGOCYTOSIS
THE ANTIMICROBIAL FUNCTIONS OF MACROPHAGES
VASCULAR MODULATORY FUNCTIONS OF MACROPHAGES
PART III MACROPHAGES IN DIFFERENT TISSUES
AIRWAY MACROPHAGES: SENTINELS OF HEALTH
MICROGLIAL ONTOGENY AND FUNCTIONS IN SHAPING BRAIN CIRCUITS
KUPFFER CELLS IN HEALTH AND DISEASE
INTESTINAL MACROPHAGES: SPECIALIZED ANTIGEN-PRESENTING CELLS AT THE
FRONT LINE
PART IV MACROPHAGES IN PATHOLOGY
THE WOUND MACROPHAGE - MACROPHAGES AND THE ENTRANCE OF RESOLUTION PHASE
LIPID MEDIATORS
MACROPHAGES IN SEPSIS PROGRESSION
ADAPTIVE CHARACTERISTICS OF INNATE IMMUNE RESPONSES IN MACROPHAGES
AFRICAN TRYPANOSOMIASIS AS PARADIGM FOR INVOLVEMENT OF THE MONONUCLEAR
PHAGOCYTE SYSTEM IN PATHOGENICITY DURING PARASITE INFECTION
MACROPHAGES IN OBESITY AND INSULIN RESISTANCE
MACROPHAGES GOVERN THE PROGRESSION AND TERMINATION OF INFLAMMATION IN
ATHEROSCLEROSIS AND METABOLIC DISEASES
MYELOMONOCYTIC SUBSETS IN TUMOR MICROENVIRONMENT
TUMOR ASSOCIATED MACROPHAGES
PART V TRANSCRIPTIONAL AND EPIGENETIC MECHANISMS
ROLE OF NF-KB ACTIVATION IN MACROPHAGES
INTERFERON REGULATORY FACTORS: ROLE IN TRANSCRIPTIONAL REGULATION OF
MACROPHAGE PLASTICITY AND ACTIVATION
KRUPPEL-LIKE FACTORS IN MONOCYTE-MACROPHAGE BIOLOGY
REGULATION OF MACROPHAGE POLARIZATION BY THE STAT-SOCS SIGNALING AXIS
FUNCTIONS OF THE LARGE MAF TRANSCRIPTION FACTORS AND MACROPHAGES
THE CONTROL OF GENE EXPRESSION IN MACROPHAGES
ROLE OF MICRORNA IN MACROPHAGE ACTIVATION AND POLARIZATION
PART VI SYSTEMS BIOLOGY OF MACROPHAGES
THE MACROPHAGE TRANSCRIPTOME
OMICS APPROACHES IN MACROPHAGE BIOLOGY
APPENDIX
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
MACROPHAGES: BIOLOGY AND ROLE IN THE PATHOLOGY OF DISEASES
/
: 2014
ABSTRACT / INHALTSTEXT
MACROPHAGES ARE A KEY COMPONENT OF THE INNATE IMMUNE SYSTEM AND PLAY AN
INTEGRAL ROLE IN HOST DEFENSE AND HOMEOSTASIS. ON ONE HAND, THESE CELLS
CONTRIBUTE TO HOST DEFENCE BY TRIGGERING INFLAMMATION, DISPLAYING
MICROBICIDAL/TUMORICIDAL PROPERTIES, REGULATING THE ACTIVATION OF
ADAPTIVE IMMUNITY AND PROMOTING RESOLUTION OF INFLAMMATION.ON THE
OTHER HAND, THEY CONTRIBUTE TO ESSENTIAL TROPHIC FUNCTIONS SUCH AS
NEURAL PATTERNING, BONE MORPHOGENESIS AND DUCTAL BRANCHING IN MAMMARY
GLANDS.THUS, MACROPHAGES ARE EXTREMELY VERSATILE CELLS THAT CAN
RESPOND EFFICIENTLY TO TISSUE MICROENVIRONMENTAL CUES BY POLARIZING TO
DISTINCT PHENOTYPES, DEPENDING ON THE FUNCTIONS THEY NEED TO PERFORM.
INDEED, FUNCTIONAL DIVERSITY AND PLASTICITY ARE HALLMARKS OF THESE
CELLS. MACROPHAGES MAY ALSO PLAY A DETRIMENTAL ROLE. AN OVERWHELMING
BODY OF LITERATURE HAS INDICATED THEIR CRUCIAL ROLE IN PATHOGENESIS. THE
LIST INCLUDES SEPSIS, CANCER, METABOLIC SYNDROME, IMMUNODEFICIENCY,
AUTO-IMMUNE DISEASE- VIRTUALLY IMPACTING EVERY MAJOR PATHOLOGY THAT WE
KNOW. THESE OBSERVATIONS HAVE SUGGESTED MACROPHAGES AND THEIR RELATED
MOLECULES AS POTENTIAL TARGETS IN THERAPEUTIC APPLICATIONS. AVAILABLE
EVIDENCE PROCLAIMS MACROPHAGES AS A KEY PLAYER IN HOMEOSTASIS, HOST
DEFENSE AND DISEASE. CRUCIAL DEVELOPMENTS IN THE PAST FEW YEARS CALL FOR
A RE-EVALUATION AND UPDATE OF OUR UNDERSTANDING OF MACROPHAGES.THE
PRESENT BOOK IS AN ENDEAVOUR THAT ATTEMPTS TOPROVIDE STATE-OF-THE ART
KNOWLEDGE OF THESE CELLS IN HEALTH AND DISEASE
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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discipline | Biologie Medizin |
doi_str_mv | 10.1007/978-1-4939-1311-4 |
format | Electronic eBook |
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isbn | 9781493913114 |
language | English |
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spelling | Macrophages: Biology and Role in the Pathology of Diseases Subhra K. Biswas ; Alberto Mantovani, ed. New York, NY [u.a.] Springer 2014 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Medizin Medicine Immunology Monoclonal antibodies Microbiology Biomedicine Biswas, Subhra K. Sonstige oth Mantovani, Alberto Sonstige oth Erscheint auch als Druckausgabe 978-1-4939-1310-7 https://doi.org/10.1007/978-1-4939-1311-4 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027663779&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027663779&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
spellingShingle | Macrophages: Biology and Role in the Pathology of Diseases Medizin Medicine Immunology Monoclonal antibodies Microbiology Biomedicine |
title | Macrophages: Biology and Role in the Pathology of Diseases |
title_auth | Macrophages: Biology and Role in the Pathology of Diseases |
title_exact_search | Macrophages: Biology and Role in the Pathology of Diseases |
title_full | Macrophages: Biology and Role in the Pathology of Diseases Subhra K. Biswas ; Alberto Mantovani, ed. |
title_fullStr | Macrophages: Biology and Role in the Pathology of Diseases Subhra K. Biswas ; Alberto Mantovani, ed. |
title_full_unstemmed | Macrophages: Biology and Role in the Pathology of Diseases Subhra K. Biswas ; Alberto Mantovani, ed. |
title_short | Macrophages: Biology and Role in the Pathology of Diseases |
title_sort | macrophages biology and role in the pathology of diseases |
topic | Medizin Medicine Immunology Monoclonal antibodies Microbiology Biomedicine |
topic_facet | Medizin Medicine Immunology Monoclonal antibodies Microbiology Biomedicine |
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