Trichloroethylene: Toxicity and health risks:
A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used...
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
London [u.a.]
Humana Press
2014
|
| Schriftenreihe: | Molecular and integrative toxicology
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Zusammenfassung: | A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used to predict functional consequences and to dissect the contribution of different mechanistic pathways, including potential mechanisms of action for trichloroethylene toxicity in different organ systems. It will explore the role of epigenetic alterations in trichloroethylene toxicity, this provides important mechanistic information and may also provide the basis for intervention therapy. Chapters will also explain how the risks from trichloroethylene exposure may be greater in certain populations based on genetic predisposition, age of exposure and co-exposure to other chemicals With contributions from international experts in the field, Trichloroethylene: Toxicity and Health Risks is an essential resource for researchers and clinicians in toxicology, immunology, medicine and public health as well as industry and government regulatory scientists involved in safety and health protection and epidemiologists, highlighting the need for interdisciplinary cooperation in solving issues of environmental toxicity |
| Beschreibung: | X, 245 S. Ill., graph. Darst. |
| ISBN: | 1447163109 9781447163107 |
Internformat
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| 490 | 0 | |a Molecular and integrative toxicology | |
| 520 | 1 | |a A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used to predict functional consequences and to dissect the contribution of different mechanistic pathways, including potential mechanisms of action for trichloroethylene toxicity in different organ systems. It will explore the role of epigenetic alterations in trichloroethylene toxicity, this provides important mechanistic information and may also provide the basis for intervention therapy. Chapters will also explain how the risks from trichloroethylene exposure may be greater in certain populations based on genetic predisposition, age of exposure and co-exposure to other chemicals With contributions from international experts in the field, Trichloroethylene: Toxicity and Health Risks is an essential resource for researchers and clinicians in toxicology, immunology, medicine and public health as well as industry and government regulatory scientists involved in safety and health protection and epidemiologists, highlighting the need for interdisciplinary cooperation in solving issues of environmental toxicity | |
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Datensatz im Suchindex
| _version_ | 1804152651807457280 |
|---|---|
| adam_text | Contents
1
History of TCE
............................................
I
Richard E. Doherty
2
THchloroethylene and Autoimmunity in Human
and Animal Models
........................................ 15
Kathleen M. Gilbert
3
Hypersensitivity
Dermatitis
and Hepatitis
..................... 37
Michihiro Kamijima, Hailan Wang,
Osamu
Yamanoshita,
Yuki
Ito,
and
Tamie
Nakajima
4
Trichloroethvlenc-Induced Oxidative
Stress and Autoimmunity
................................... 53
M. Firoze Khan and Gangduo Wang
5
Brain and Behavioral Changes in Rodent Models
............... 73
Ambuja S. Bale
6
Role of Trichloroethylene in Parkinson s Disease
................ 91
Samuel M. Goldman and Stephanie Whisnant Cash
7
Neuroimmune
Effects of Developmental
TCE Exposure
............................................ 131
Sarah J. Blossom
8
Environmental Sensitivity to Trichloroethylene
(TCE) in the Developing Heart
............................... 153
Omelia
I. Selmin. Om Makwana. and Raymond B. Runyan
9
Trichloroethylene and Cancer
............................... 171
Daniel
Wartenberg
and Kathleen M. Gilbert
χ
Contents
10 Epigenetic
Alterations due to TricMoroethylene
................. 185
Craig A. Cooney
11
Mathematical Modeling and Trichloroethylene
................. 209
Brad
Reisfeld
and Jaime H. Ivy
About the Editors
.............................................. 239
Index
........................................................ 241
Molecular and
integrative
Toxicology
Series Editor: Rodney R. Dietert
Kathleen M. Gilbert
■
Sarah J. Blossom Editors
Trichloroethylene:
Toxicity
and Health Risks
A comprehensive overview of the effects of trichloroethylene
toxicity
caused by real-
Hfe exposure levels highlighting how exposure to trichloroethylene may contribute to
the etiology of several idiopathic human diseases. Discussion will focus on different
kinds of modeling and how they may be used to predict functional consequences and
to dissect the contribution of different mechanistic pathways, including potential
mechanisms of action for trichloroethylene
toxicity
in different organ systems. It will
explore the role of epigenetic alterations in trichloroethylene
toxicity,
this provides
important mechanistic information and may also provide the basis for intervention
therapy. Chapters will also explain how the risks from trichloroethylene exposure may
be greater in certain populations based on genetic predisposition, age of exposure, and
co-exposure to other chemicals.
With contributions from international experts in the field Trichloroethylene;
Toxicity
anã
Health Risks is an essential resource for researchers and clinicians in toxicology,
immunology, medicine and public health as well as industry and government regulatory
scientists involved in safety and health protection and epidemiologists, highlighting
the need for interdisciplinary cooperation in solving issues of environmental
toxicity.
|
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| spelling | Trichloroethylene: Toxicity and health risks Kathleen M. Gilbert ; Sarah J. Blossom, ed. London [u.a.] Humana Press 2014 X, 245 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular and integrative toxicology A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used to predict functional consequences and to dissect the contribution of different mechanistic pathways, including potential mechanisms of action for trichloroethylene toxicity in different organ systems. It will explore the role of epigenetic alterations in trichloroethylene toxicity, this provides important mechanistic information and may also provide the basis for intervention therapy. Chapters will also explain how the risks from trichloroethylene exposure may be greater in certain populations based on genetic predisposition, age of exposure and co-exposure to other chemicals With contributions from international experts in the field, Trichloroethylene: Toxicity and Health Risks is an essential resource for researchers and clinicians in toxicology, immunology, medicine and public health as well as industry and government regulatory scientists involved in safety and health protection and epidemiologists, highlighting the need for interdisciplinary cooperation in solving issues of environmental toxicity Medizin Medicine Immunology Toxicology Biochemistry Epidemiology Environmental Medicine Toxikologie (DE-588)4060538-3 gnd rswk-swf Trichlorethylen (DE-588)4186064-0 gnd rswk-swf Trichlorethylen (DE-588)4186064-0 s Toxikologie (DE-588)4060538-3 s b DE-604 Gilbert, Kathleen M. Sonstige oth Blossom, Sarah J. Sonstige oth Erscheint auch als Online-Ausgabe 978-1-4471-6311-4 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027596489&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027596489&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Trichloroethylene: Toxicity and health risks Medizin Medicine Immunology Toxicology Biochemistry Epidemiology Environmental Medicine Toxikologie (DE-588)4060538-3 gnd Trichlorethylen (DE-588)4186064-0 gnd |
| subject_GND | (DE-588)4060538-3 (DE-588)4186064-0 |
| title | Trichloroethylene: Toxicity and health risks |
| title_auth | Trichloroethylene: Toxicity and health risks |
| title_exact_search | Trichloroethylene: Toxicity and health risks |
| title_full | Trichloroethylene: Toxicity and health risks Kathleen M. Gilbert ; Sarah J. Blossom, ed. |
| title_fullStr | Trichloroethylene: Toxicity and health risks Kathleen M. Gilbert ; Sarah J. Blossom, ed. |
| title_full_unstemmed | Trichloroethylene: Toxicity and health risks Kathleen M. Gilbert ; Sarah J. Blossom, ed. |
| title_short | Trichloroethylene: Toxicity and health risks |
| title_sort | trichloroethylene toxicity and health risks |
| topic | Medizin Medicine Immunology Toxicology Biochemistry Epidemiology Environmental Medicine Toxikologie (DE-588)4060538-3 gnd Trichlorethylen (DE-588)4186064-0 gnd |
| topic_facet | Medizin Medicine Immunology Toxicology Biochemistry Epidemiology Environmental Medicine Toxikologie Trichlorethylen |
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