Influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
Berlin
Mensch und Buch Verl.
2014
|
| Schlagworte: | |
| Online-Zugang: | Volltext Inhaltsverzeichnis |
| Beschreibung: | Nebentitel: Einfluss von Zinkoxid auf morphologische und immunologische Charakteristika im Jejunum und Kolon von abgesetzten Ferkeln |
| Beschreibung: | V, 107 S. Ill., graph. Darst. |
| ISBN: | 9783863875220 |
Internformat
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| 245 | 1 | 0 | |a Influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets |c vorgelegt von Ping Liu |
| 246 | 1 | 3 | |a Einfluss von Zinkoxid auf morphologische und immunologische Charakteristika im Jejunum und Kolon von abgesetzten Ferkeln |
| 264 | 1 | |a Berlin |b Mensch und Buch Verl. |c 2014 | |
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| 500 | |a Nebentitel: Einfluss von Zinkoxid auf morphologische und immunologische Charakteristika im Jejunum und Kolon von abgesetzten Ferkeln | ||
| 502 | |a Berlin, Freie Univ., Diss., 2014 | ||
| 650 | 7 | |a colon |2 cabt | |
| 650 | 7 | |a jejunum |2 cabt | |
| 650 | 7 | |a immune response |2 cabt | |
| 650 | 7 | |a morphology |2 cabt | |
| 650 | 7 | |a mucins |2 cabt | |
| 650 | 7 | |a piglets |2 cabt | |
| 650 | 7 | |a diarrhea |2 cabt | |
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Datensatz im Suchindex
| _version_ | 1804152625166286848 |
|---|---|
| adam_text | CONTENT
CONTENT
LIST OF TABLES III
LIST OF FIGURES IV
LIST OF ABBREVIATIONS V
CHAPTER 1: INTRODUCTION 1
CHAPTER 2: LITERATURE REVIEW 3
2.1 INNATE BARRIER AT GASTROINTESTINAL TRACT 3
2.1.1 MUCINS 4
2.1.2 TREFOIL FACTORS 7
2.1.3 ANTIMICROBIAL PEPTIDES 8
2.1.4 TOLL-LIKE RECEPTORS 9
2.2 CHARACTERISTICS ASSOCIATED WITH WEANING IN PIGLETS 10
2.2.1 CHANGES IN GUT MORPHOLOGY OF WEANED PIGLETS 10
2.2.2 INTESTINAL IMMUNE RESPONSE OF WEANED PIGLETS 10
2.3 ROLE OF THE TRACE ELEMENT ZINC IN THE GASTROINTESTINAL TRACT 10
CHAPTER 3: OBJECTIVES 14
CHAPTER 4: EFFECT OF DIETARY ZINC OXIDE ON JEJUNAL MORPHOLOGICAL AND
IMMUNOLOGICAL CHARACTERISTICS IN WEANED PIGLETS IS
4.1 INTRODUCTION 17
4.2 MATERIAL AND METHODS 17
4.2.1 ANIMALS, DIETS AND SAMPLING 18
4.2.2 HISTOCHEMISTRY 19
4.2.3 FLOW CYTOMETRIC ANALYSIS 20
4.2.4 RNA EXTRACTION AND GENE EXPRESSION ANALYSIS 21
4.2.5 STATISTICAL ANALYSIS 21
4.3 RESULTS 22
4.3.1 MORPHOMETRIC DATA OF VILLUS HEIGHT AND CRYPT DEPTH IN THE JEJUNUM
22
4.3.2 MUCIN CHEMOTYPES IN JEJUNAL GOBLET CELLS 22
4.3.3 PHENOTYPING OF INTRAEPITHELIAL LYMPHOCYTES 23
4.3.4 GENE EXPRESSION IN THE JEJUNUM 23
4.4 DISCUSSION 24
CHAPTER 5: EFFECT OF DIETARY ZINC OXIDE ON MORPHOLOGICAL
CHARACTERISTICS, MUCIN
COMPOSITION AND GENE EXPRESSION IN THE COLON OF WEANED PIGLETS 42
5.1 INTRODUCTION 43
5.2 MATERIALS AND METHODS 45
5.2.1 ANIMALS, HOUSING AND DIETS 45
5.2.2 SAMPLING 45
5.2.3 HISTOCHEMISTRY OF THE COLON 46
5.2.4 RNA EXTRACTION AND GENE EXPRESSION IN COLON BY REAL-TIME PCR 47
HTTP://D-NB.INFO/1058089102
CONTENT
5.2.5 STATISTICAL ANALYSIS 48
5.3 RESULTS 48
5.3.1 MORPHOMETRIC MEASUREMENTS 48
5.3.2 MUCIN CHEMOTYPES IN GOBLET CELLS 48
5.3.3 MRNA EXPRESSION IN THE COLONIC TISSUE 49
5.4 DISCUSSION 49
5.5 CONCLUSIONS 54
5.6 ACKNOWLEDGEMENTS 55
CHAPTER 6: DISCUSSION 69
6.1 EFFECT OF DIETARY ZINC OXIDE ON MORPHOLOGICAL CHARACTERISTICS IN THE
INTESTINE 69
6.2 EFFECT OF DIETARY ZINC OXIDE ON MUCIN DISTRIBUTION 71
6.3 EFFECT OF DIETARY ZINC OXIDE ON MUCIN CHEMOTYPES IN GOBLET CELLS 72
6.4 EFFECT OF DIETARY ZINC OXIDE ON INTRAEPITHELIAL LYMPHOCYTES IN THE
JEJUNUM 75
6.5 EFFECT OF DIETARY ZINC OXIDE ON GENE EXPRESSION RELATED TO IMMUNE
RESPONSE.... 76
CHAPTER 7: SUMMARY/ZUSAMMENFASSUNG 80
REFERENCES 86
PUBLICATION LIST 104
ACKNOWLEDGEMENTS 105
SELBSTSTSNDIGKEITSERKURUNG 107
|
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| spelling | Liu, Ping Verfasser (DE-588)1058451456 aut Influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets vorgelegt von Ping Liu Einfluss von Zinkoxid auf morphologische und immunologische Charakteristika im Jejunum und Kolon von abgesetzten Ferkeln Berlin Mensch und Buch Verl. 2014 V, 107 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Nebentitel: Einfluss von Zinkoxid auf morphologische und immunologische Charakteristika im Jejunum und Kolon von abgesetzten Ferkeln Berlin, Freie Univ., Diss., 2014 colon cabt jejunum cabt immune response cabt morphology cabt mucins cabt piglets cabt diarrhea cabt zinc oxide cabt Morphologie Biologie (DE-588)4407742-7 gnd rswk-swf Zinkoxid (DE-588)4190864-8 gnd rswk-swf Immunsystem (DE-588)4026643-6 gnd rswk-swf Absatzferkel (DE-588)4251192-6 gnd rswk-swf Darm (DE-588)4011061-8 gnd rswk-swf Futterzusatz (DE-588)4155774-8 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Absatzferkel (DE-588)4251192-6 s Futterzusatz (DE-588)4155774-8 s Zinkoxid (DE-588)4190864-8 s Darm (DE-588)4011061-8 s Morphologie Biologie (DE-588)4407742-7 s Immunsystem (DE-588)4026643-6 s DE-604 Erscheint auch als Online-Ausgabe urn:nbn:de:kobv:188-fudissthesis000000097461-4 http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000097461 kostenfrei Volltext DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027580351&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Liu, Ping Influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets colon cabt jejunum cabt immune response cabt morphology cabt mucins cabt piglets cabt diarrhea cabt zinc oxide cabt Morphologie Biologie (DE-588)4407742-7 gnd Zinkoxid (DE-588)4190864-8 gnd Immunsystem (DE-588)4026643-6 gnd Absatzferkel (DE-588)4251192-6 gnd Darm (DE-588)4011061-8 gnd Futterzusatz (DE-588)4155774-8 gnd |
| subject_GND | (DE-588)4407742-7 (DE-588)4190864-8 (DE-588)4026643-6 (DE-588)4251192-6 (DE-588)4011061-8 (DE-588)4155774-8 (DE-588)4113937-9 |
| title | Influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets |
| title_alt | Einfluss von Zinkoxid auf morphologische und immunologische Charakteristika im Jejunum und Kolon von abgesetzten Ferkeln |
| title_auth | Influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets |
| title_exact_search | Influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets |
| title_full | Influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets vorgelegt von Ping Liu |
| title_fullStr | Influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets vorgelegt von Ping Liu |
| title_full_unstemmed | Influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets vorgelegt von Ping Liu |
| title_short | Influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets |
| title_sort | influence of dietary zinc oxide on morphological and immunological characteristics in the jejunum and colon of weaned piglets |
| topic | colon cabt jejunum cabt immune response cabt morphology cabt mucins cabt piglets cabt diarrhea cabt zinc oxide cabt Morphologie Biologie (DE-588)4407742-7 gnd Zinkoxid (DE-588)4190864-8 gnd Immunsystem (DE-588)4026643-6 gnd Absatzferkel (DE-588)4251192-6 gnd Darm (DE-588)4011061-8 gnd Futterzusatz (DE-588)4155774-8 gnd |
| topic_facet | colon jejunum immune response morphology mucins piglets diarrhea zinc oxide Morphologie Biologie Zinkoxid Immunsystem Absatzferkel Darm Futterzusatz Hochschulschrift |
| url | http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000097461 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027580351&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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