Cancers in people with HIV and AIDS: progress and challenges ; this book is an expansion of the section Opportunistic malignancies, in the Encyclopedia of AIDS ...
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
New York, NY [u.a.]
Springer
2014
|
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis Klappentext |
Beschreibung: | XVI, 389 S. Ill., graph. Darst., Kt. |
ISBN: | 9781493908585 |
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Datensatz im Suchindex
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adam_text | Contents
Part I Overview and Epidemiology
1
HIV-Associated Cancers
......................................................................... 3
Robert Yarchoan, Thomas S. Uldrick, and Mark
N.
Polizzotto
2
Epidemiology of AIDS-Definmg Malignancies
..................................... 17
William A.
Blattner
and Rebecca G.
Nowak
3
The Epidemiology of Non-AIDS-Defining Malignancies
..................... 31
Andrew E. Grulich
4 HIV
Cancers in Resource-Limited Regions
.......................................... 43
Sam M. Mbulaiteye
Part II Oncogenic Viruses Causing HIV-Associated Cancers
5
Kaposi Sarcoma-Associated Herpesvirus (KSHV)
or Human Herpesvirus
8
(HHV-8)
........................................................ 61
Blossom Damania and Dirk P- Ditttner
6
Epstein-Barr Virus
................................................................................. 75
Lindsey Hutt- Fletcher
7
Human
Papillomavíruses
....................................................................... 87
Zhi-Ming Zheng
8 Merkel
Cell Polyomavirus
...................................................................... 113
Nicole Fischer and Adam
Grundhoff
IX
x
Contents
Part
III Kaposi
Sarcoma
9
Presentation and Pathogenesis of Kaposi Sarcoma
............................. 125
Corey Casper
10
Management of AIDS-Related Kaposi Sarcoma
.................................. 139
Susan E. Krown
Part IV HIV-Associated Lymphomas and Lymphoproliferative
Diseases
11
Presentation and Pathogenesis of B-Cell Lymphoid
Cancers Associated with
HIV
Infection
................................................ 155
Richard F. Little,
Stefania Pittaluga,
and Kieron Dunleavy
12
Diffuse Large B-Cell Lymphoma
........................................................... 175
Neel K. Gupta and Lawrence D. Kaplan
13
Burkitt and Burkitt-Like Lymphoma
................................................... 183
Kishor Bhatia and Sam M. Mbulaiteye
14
Primary Effusion Lymphoma
................................................................ 195
Giovanna Tosato
15
AIDS-Related Primary Central Nervous System Lymphoma
............ 207
Jan Davidson-
Mone
ada
and Thomas S. Uldrick
16
Plasmablastic Lymphoma
...................................................................... 223
Huan-You Wang, Ida Wong-Seridan, and Erin Reid
17
Hodgkin
Lymphoma in Patients with
HIV
Infection
........................... 235
Michele Spina,
Rosanna
Ciancia, Accursio Augello,
Massimiliano Berretta, and Umberto Tirelli
18
Multicentric Castleman
Disease
............................................................ 245
Mark
N.
Poîizzotto, Thomas S. Uldrick, and Robert Yarchoan
Part
V Human Papillomavirus-
Associated Cancers
19
Cervical Cancer and
HIV....................................................................... 263
Elizabeth
A.
Stier
20
Anal Cancer
............................................................................................. 273
Joel
M. Palefsky
21
Other
HPV-Associated Cancers (Oropharyngeal and
Penile)
............ 289
Kristina
R.
Dahlström and
Erich
M. Sturgis
Contents xi
Part VI Other
HIV-
Associated
Cancers
22
Lung Cancer in
HIV
Infection
............................................................... 301
Deepthi
Mani
and David M. Aboulafia
23
Hepatocellular Carcinoma in HIV-Positive Patients
........................... 313
Massimiliano
Berretta,
Paolo
De Paoli, Umberto
ТігеШ,
and Bruno Cacopardo
24 Merkel
Celi Carcinoma
and Other
HIV-
Associated
Skin Cancers
............................................................................................ 327
Nathalie C. Zeitouni and Bethany
Lema
25
Conjunctival Carcinoma
........................................................................ 339
Kenneth O. Simbiri and
Erle S.
Robertson
26
Malignancies in Children with
HIV
Infection
...................................... 349
D.
Cristina
Stefan
Part
VII
Supportive and Therapeutic Strategies
27
cART and Supportive Care for HIV-Associated Malignancies
.......... 361
Ronald T.
Mits
uy
asu
28
Stem Cell Transplantation
...................................................................... 367
Christine
Durand
and Richard
Ambinder
Index
................................................................................................................. 379
Robert Yarchoan
Editor
Cancers in People with
HIV
and AIDS
Progress and Challenges
The association between AIDS and cancer was recognized from the beginning of
the AIDS epidemic, when the appearance of Kaposi sarcoma in a cluster of young
men was one of the first signs of this new disease. It was soon recognized that AIDS
patients are prone to develop a number of AIDS-defining cancers: Kaposi sarcoma,
lymphoma, and cervical cancer. The development of effective combination anti-HIV
therapy starting around
1996
converted AIDS from a death sentence to a manageable
disease and led to dramatic shifts in the epidemic. As this therapy was able to improve
immune function in patients, the incidence of most AIDS-defining cancers decreased.
There is a misconception, however, that AIDS has gone away. In fact, as AIDS patients
are living longer, the number of AIDS patients has more than doubled in the United
States since
1996,
and the AIDS population overall has increased in age. Also, as AIDS
patients are less likely to die of other complications, cancer is coming to the forefront
as one of the most common causes of death in regions where AIDS drugs are widely
available. Moreover, the three AIDS-defining cancers are now taking a back seat to
a number of other HIV-associated cancers, such as
Hodgkin
lymphoma, lung cancer,
and anal cancer. In the developing world, AIDS-associated cancers are a major public
health problem, and in some regions of sub-Saharan Africa, Kaposi sarcoma is the
most common tumor in men.
In recent years, there has been a vast increase in our understanding of HI V-associated
cancers. We now know, for example, that most are caused by other viruses and that
the main role of
HIV
and immunodeficiency is to provide a supportive environment
for the viruses to multiply and for the cancers to develop. But there remain a number
of unanswered questions and a need for improved prevention and therapy. In the
28
chapters of this book, written by some of the most renowned experts in this field, we
present up-to-date information on the cancers associated with
HIV
infection. The
chapters cover the epidemiology of these cancers, as well as their pathogenesis, clinical
presentation, and treatment.
Dr,
Robert Yarchoan is the Director of the Office of
HIV
and AIDS Malignancy and
Chief of the
HIV
and AIDS Malignancy Branch in the National Cancer Institute. He
played a major role in developing the first AIDS drugs. His research is now focused on
AIDS-related cancers, especially Kaposi sarcoma and other cancers caused by Kaposi
sarcoma-associated herpesvirus.
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spellingShingle | Cancers in people with HIV and AIDS progress and challenges ; this book is an expansion of the section Opportunistic malignancies, in the Encyclopedia of AIDS ... Medizin Medicine Immunology Medical virology Emerging infectious diseases Oncology Biomedicine HIV-Infektion (DE-588)4203852-2 gnd Krebs Medizin (DE-588)4073781-0 gnd |
subject_GND | (DE-588)4203852-2 (DE-588)4073781-0 (DE-588)4143413-4 |
title | Cancers in people with HIV and AIDS progress and challenges ; this book is an expansion of the section Opportunistic malignancies, in the Encyclopedia of AIDS ... |
title_auth | Cancers in people with HIV and AIDS progress and challenges ; this book is an expansion of the section Opportunistic malignancies, in the Encyclopedia of AIDS ... |
title_exact_search | Cancers in people with HIV and AIDS progress and challenges ; this book is an expansion of the section Opportunistic malignancies, in the Encyclopedia of AIDS ... |
title_full | Cancers in people with HIV and AIDS progress and challenges ; this book is an expansion of the section Opportunistic malignancies, in the Encyclopedia of AIDS ... Robert Yarchoan, ed. |
title_fullStr | Cancers in people with HIV and AIDS progress and challenges ; this book is an expansion of the section Opportunistic malignancies, in the Encyclopedia of AIDS ... Robert Yarchoan, ed. |
title_full_unstemmed | Cancers in people with HIV and AIDS progress and challenges ; this book is an expansion of the section Opportunistic malignancies, in the Encyclopedia of AIDS ... Robert Yarchoan, ed. |
title_short | Cancers in people with HIV and AIDS |
title_sort | cancers in people with hiv and aids progress and challenges this book is an expansion of the section opportunistic malignancies in the encyclopedia of aids |
title_sub | progress and challenges ; this book is an expansion of the section Opportunistic malignancies, in the Encyclopedia of AIDS ... |
topic | Medizin Medicine Immunology Medical virology Emerging infectious diseases Oncology Biomedicine HIV-Infektion (DE-588)4203852-2 gnd Krebs Medizin (DE-588)4073781-0 gnd |
topic_facet | Medizin Medicine Immunology Medical virology Emerging infectious diseases Oncology Biomedicine HIV-Infektion Krebs Medizin Aufsatzsammlung |
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