Epigenetics:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier
2014
|
| Ausgabe: | 1. ed. |
| Schriftenreihe: | International review of neurobiology
115 |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XIII, 332 S. Ill., graph. Darst. |
| ISBN: | 9780128013113 |
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Datensatz im Suchindex
| _version_ | 1804152512654082048 |
|---|---|
| adam_text | Titel: Epigenetics
Autor: Pandey, Subhash C
Jahr: 2014
CONTENTS
Contributors ix
Preface xi
1. Environmental Alterations of Epigenetics Prior to the Birth 1
Chiao-Ling Lo and Feng C. Zhou
1. Introduction 2
2. Manifestation of Environmental Factors 4
B. Mechanisms of Environmentally Induced Eplgenetlc Changes 19
4. Effect of Epigenetlc Alterations on Neurodevelopment 25
Acknowledgments 34
References 34
2. Transgenerational Epigenetics and Brain Disorders 51
Nadia Rachdaoui and Dipak K. Sarkar
1. Introduction to Transgenerational Epigenetlc Inheritance 51
2. Epigenetics and Epigenetlc Processes 53
3. Evidence for Transgenerational Epigenetlc Inheritance 55
4. Germline-lndependent Eplgenetic Inheritance 57
5. Germline-Dependent Epigenetic Transmission 57
6. Transgenerational Epigenetlc Effects on Brain Disorders 60
7. Concluding Remarks 66
Acknowledgment 66
References 67
3. The Epigenetic Landscape of Alcoholism 75
Harish R. Krishnan, Amul J. Sakharkar, Tara L. Teppen, Tiffani D. M. Berkel,
and Subhash C. Pandey
1. Introduction 76
2. Epigenetic Regulation due to Hlstone Covalent Modifications 78
3. Epigenetic Regulation due to DNA Methylatlon 89
4. Genome-Wide Approaches to Understand the Basis of Alcoholism 98
5. Using Invertebrate Models to Study the Basis of Ethanol Phenotypes 99
6. Inheritance of a Drug Phenotype 100
7. Conclusions 101
Acknowledgments 103
References 104
vi
Contents
4. Epigenetic Regulatory Mechanisms in Stress-Induced Behavior 117
Sumana Chakravarty, Salil Saurav Pathak, Swati Maitra, Nitin Khandelwal,
Karisetty Bhanu Chandra, and Arvind Kumar
1. Introduction 118
2. Stress-Induced Neural and Behavioral changes in Adulthood and the
Epigenetic Mechanisms Involved 119
3. DNA Methylation and Demethylation in Stress-Induced Neural and Behavioral
Responses 138
4. Role of Noncodlng RNAs in Epigenetic Regulation of Stress-Mediated Effects 139
5. Early-Life Stress-Induced Adult Onset Behavioral Disorders and the Epigenetic
Mechanisms Involved 144
6. Conclusion 146
Acknowledgments 147
References 147
5. Epigenetics of Schizophrenia: An Open and Shut Case 155
David P. Gavin and Christina Floreani
1. Introduction 156
2. An Epigenetics Primer 157
3. Heterochromatization 157
4. Euchromatization 161
5. Schizophrenia and Epigenetics 167
6. Fulfilling the Promise of Epigenetics in Schizophrenia 178
7. Conclusion 184
Acknowledgments 184
References 184
Further Reading 201
6. Epigenetic Mechanisms in Autism Spectrum Disorder 203
Adrian Zhubi, Edwin H. Cook, Alessandro Guidotti, and Dennis R. Grayson
1. Introduction 204
2. Molecular Aspects of Epigenetic Mechanisms 206
3. Genetic Defects with Epigenetic Implications 213
4. Epigenetic Dysregulation of ASD Candidate Genes 218
5. Environmental Model of Autism 227
6. Conclusions 229
Acknowledgments 231
References 231
Further Reading 244
Contents
vii
7. MicroRNAs and Ethanol Toxicity 245
Rajesh C. Miranda
1. Introduction 246
2. miRNAs and Their Biogenesis 247
3. Mechanisms of miRNA Function 252
4. miRNAs as Mediators of Ethanol Effects in Developing and Adult Tissues 258
5. miRNA-Mediated Transgenerational Inheritance of Information: A Novel
Mechanism for Transgenerational Transfer of Epimutations? 271
6. Conclusions 273
Acknowledgments 275
References 275
Index 285
Contents of Previous Volumes 291
|
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| id | DE-604.BV042069212 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T01:11:54Z |
| institution | BVB |
| isbn | 9780128013113 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027509926 |
| oclc_num | 891365699 |
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| physical | XIII, 332 S. Ill., graph. Darst. |
| publishDate | 2014 |
| publishDateSearch | 2014 |
| publishDateSort | 2014 |
| publisher | Elsevier |
| record_format | marc |
| series | International review of neurobiology |
| series2 | International review of neurobiology |
| spelling | Epigenetics ed. by Subhash C. Pandey 1. ed. Amsterdam [u.a.] Elsevier 2014 XIII, 332 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier International review of neurobiology 115 Literaturangaben Pandey, Subhash C. Sonstige oth International review of neurobiology 115 (DE-604)BV002534817 115 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027509926&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Epigenetics International review of neurobiology |
| title | Epigenetics |
| title_auth | Epigenetics |
| title_exact_search | Epigenetics |
| title_full | Epigenetics ed. by Subhash C. Pandey |
| title_fullStr | Epigenetics ed. by Subhash C. Pandey |
| title_full_unstemmed | Epigenetics ed. by Subhash C. Pandey |
| title_short | Epigenetics |
| title_sort | epigenetics |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027509926&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV002534817 |
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