Gene regulation of PLK4 and KIF23 by DREAM and MMB complexes:
Gespeichert in:
1. Verfasser: | |
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Format: | Abschlussarbeit Elektronisch Software E-Book |
Sprache: | English |
Veröffentlicht: |
2013
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Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | Enth. 3 Sonderabdr. aus verschiedenen Zeitschr. |
Beschreibung: | [ca. 100] Bl. in getr. Zählung Ill., graph. Darst. 12 cm |
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Datensatz im Suchindex
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adam_text | INDEX OF CONTENTS
1 INTRODUCTION 1
1.1 THE CELL CYCLE 1
1.2 TRANSCRIPTIONAL REGULATION OF CELL CYCLE GENES 2
1.3 THE DREAM AND MMB COMPLEXES 3
1.4 P53 - THE GUARDIAN OF THE GENOME 4
1.5 THE VIRAL ONCOPROTEINS HPV E7 6
1.6 CDE/CHR AS CENTRAL ELEMENTS IN CELL CYCLE CONTROL 7
2 PUBLICATIONS 10
2.1 THE FORKHEAD TRANSCRIPTION FACTOR FOXM1 CONTROLS CELL
CYCLE-DEPENDENT GENE
EXPRESSION THROUGH AN ATYPICAL CHROMATIN BINDING MECHANISM.
CHEN X, MIILLER GA, QUAAS M, FISCHER M. HAN N, STUTCHBURY B, SHARROCKS
AD,
ENGELAND K. MOL CELL BIOL (2013) 33 (2): 227-36
2.2 DREAM AND MMB COMPLEXES CONTROL P53- AND CELL CYCLE-DEPENDENT
TRANSCRIPTION OF
KINESIN FAMILY MEMBER 23 (KIF23) VIA A CHR PROMOTER ELEMENT.
FISCHER* M, GRUNDKE* I, SOHR* S, QUAAS M, HOFFMANN S, KNORCK A, GUMHOLD
C,
ROTHER K. PLOS ONE (2013) 8 (5): E63187
2.3 POLO-LIKE KINASE 4 TRANSCRIPTION IS ACTIVATED VIA CRE AND NRF1
ELEMENTS, REPRESSED
BY DREAM THROUGH CDE/CHR SITES AND DEREGULATED BY HPV E7 PROTEIN.
FISCHER M, QUAAS M, WINTSCHE A, MIILLER GA UND ENGELAND K. NUCLEIC ACIDS
RESEARCH (2013) DOI: 10.1093/NAR/GKT849
3 DISCUSSION 11
3.1 FOXML INTERACTS WITH MMB AND REQUIRES A CHR FOR PROMOTER BINDING 11
3.2 PLK4 REQUIRES A CDE IN ADDITION TO THE CHR FOR DREAM BINDING AND
REGULATION . 11
3.3 KIF23 AND PLK4 ARE TARGETED BY THE P53-P21 -DREAM/MMB-CDE/CHR
PATHWAY 12
3.4 HPV E7 DISRUPTS DREAM BINDING TO CDE/CHR ELEMENTS INDUCING THE
EXPRESSION OF ITS TARGET GENES 13
3.5 CDE/CHR CONTROLLED PROMOTERS CAN BE ACTIVATED BY CRE AND NRF1 SITES
ALTERNATIVELY TO NF-Y-BOUND CCAAT-BOXES ...14
4 SUMMARY 15
5 ZUSAMMENFASSUNG 16
6 REFERENCES 17
ABBREVIATIONS 29
PUBLICATIONS 31
LEBENSLAUF 32
SELBSTSTANDIGKEITSERKLARUNG 33
DANKSAGUNG 34
NACHWEIS IIBER DIE ANTEILE ALLER CO-AUTOREN
HTTP://D-NB.INFO/1047271877
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spelling | Fischer, Martin 1987- Verfasser (DE-588)1047271346 aut Gene regulation of PLK4 and KIF23 by DREAM and MMB complexes vorgelegt von Martin Fischer 2013 [ca. 100] Bl. in getr. Zählung Ill., graph. Darst. 12 cm txt rdacontent c rdamedia cd rdacarrier Enth. 3 Sonderabdr. aus verschiedenen Zeitschr. Leipzig, Univ., Diss., 2013 (DE-588)4113937-9 Hochschulschrift gnd-content DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027455184&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Fischer, Martin 1987- Gene regulation of PLK4 and KIF23 by DREAM and MMB complexes |
subject_GND | (DE-588)4113937-9 |
title | Gene regulation of PLK4 and KIF23 by DREAM and MMB complexes |
title_auth | Gene regulation of PLK4 and KIF23 by DREAM and MMB complexes |
title_exact_search | Gene regulation of PLK4 and KIF23 by DREAM and MMB complexes |
title_full | Gene regulation of PLK4 and KIF23 by DREAM and MMB complexes vorgelegt von Martin Fischer |
title_fullStr | Gene regulation of PLK4 and KIF23 by DREAM and MMB complexes vorgelegt von Martin Fischer |
title_full_unstemmed | Gene regulation of PLK4 and KIF23 by DREAM and MMB complexes vorgelegt von Martin Fischer |
title_short | Gene regulation of PLK4 and KIF23 by DREAM and MMB complexes |
title_sort | gene regulation of plk4 and kif23 by dream and mmb complexes |
topic_facet | Hochschulschrift |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027455184&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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