Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes:
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1. Verfasser: | |
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Format: | Abschlussarbeit Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Cham [u.a.]
Springer
2014
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Schriftenreihe: | Springer Theses
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Schlagworte: | |
Online-Zugang: | UBT01 Volltext Inhaltsverzeichnis Abstract |
Beschreibung: | 1 Online-Ressource |
ISBN: | 9783319066295 |
DOI: | 10.1007/978-3-319-06629-5 |
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Datensatz im Suchindex
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adam_text | SPECTROSCOPIC AND MECHANISTIC STUDIES OF DINUCLEAR METALLOHYDROLASES AND
THEIR BIOMIMETIC COMPLEXES
/ DAUMANN, LENA JOSEFINE
: 2014
TABLE OF CONTENTS / INHALTSVERZEICHNIS
INTRODUCTION
EXPERIMENTAL
UNDERSTANDING THE OVERALL STRUCTURE OF GPDQ AND METAL BINDING
STRUCTURAL AND MECHANISTIC STUDIES OF ZN(II) COMPLEXES AS
PHOSPHOESTERASE MODELS
MECHANISTIC STUDIES OF CD(II) COMPLEXES AS PHOSPHOESTERASE AND
METALLO-Β-LACTAMASE MODELS
SPECTROSCOPIC AND MECHANISTIC STUDIES OF CO(II) PHOSPHOESTERASE AND
METALLO-Β-LACTAMASE BIOMIMETICS
ASYMMETRIC ZN(II) COMPLEXES AS STRUCTURAL AND FUNCTIONAL MODELS FOR GPDQ
IMMOBILIZATION OF GPDQ AND RELATED MODELS FOR BIOREMEDIAL APPLICATIONS
CONCLUSION AND OUTLOOK
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
SPECTROSCOPIC AND MECHANISTIC STUDIES OF DINUCLEAR METALLOHYDROLASES AND
THEIR BIOMIMETIC COMPLEXES
/ DAUMANN, LENA JOSEFINE
: 2014
ABSTRACT / INHALTSTEXT
LENA DAUMANNS S THESIS DESCRIBES STRUCTURAL AND FUNCTIONAL STUDIES OF
THE ENZYME GLYCEROPHOSPHODIESTERASE (GPDQ) FROM ENTEROBACTER AEROGENES.
IT ALSO EXAMINES THE PROPERTIES OF SMALL MIMICS OF THIS ENZYME AND
RELATED BINUCLEAR METALLOHYDROLASES SUCH AS THE METALLO-SS-LACTAMASES TO
ENHANCE OUR UNDERSTANDING OF HYDROLYTIC CLEAVAGE OF IMPORTANT SUBSTRATES
LIKE PHOSPHOESTERS AND Β-LACTAMS. OVERALL, THIS PROJECT HAS LED TO A
BETTER UNDERSTANDING OF THE METAL ION BINDING AND ACTIVE SITE STRUCTURAL
FEATURES OF THE ENZYME GPDQ. DAUMANN DESCRIBES HOW SHE SUCCESSFULLY
IMMOBILIZED PHOSPHOESTERASE AND RELATED BIOMIMETICS ON SOLID SUPPORTS
FOR POTENTIAL APPLICATIONS IN THE AREA OF BIOREMEDIATION OF
ORGANOPHOSPHATE PESTICIDES. ANALYSIS SHOWS THAT BOTH THE ENZYME AND
BIOMIMETICS CAN BE STORED ON THE SOLID SUPPORT WITHOUT LOSS OF ACTIVITY.
FURTHERMORE, THE AUTHOR SPECROSCOPICALLY AND MECHANISTICALLY
CHARACTERIZED A NUMBER OF ZN(II), CD(II) AND CO(II) COMPLEXES, SOME OF
WHICH ARE AMONG THE MOST ACTIVE BIOMIMETICS TOWARDS ORGANOPHOSPHATES
REPORTED TO DATE. THIS THESIS MAKES EXCELLENT READING FOR
NON-SPECIALISTS BECAUSE EACH CHAPTER INCLUDES A SHORT INTRODUCTION
SECTION
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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spelling | Daumann, Lena Josefine Verfasser aut Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes Lena Josefine Daumann Cham [u.a.] Springer 2014 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Springer Theses Zugl.: [Brisbane], University of Queensland, Diss. Chemie Spectroscopy Biochemical engineering Enzymes Chemistry (DE-588)4113937-9 Hochschulschrift gnd-content Erscheint auch als Druckausgabe 978-3-319-06628-8 https://doi.org/10.1007/978-3-319-06629-5 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027364074&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027364074&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
spellingShingle | Daumann, Lena Josefine Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes Chemie Spectroscopy Biochemical engineering Enzymes Chemistry |
subject_GND | (DE-588)4113937-9 |
title | Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes |
title_auth | Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes |
title_exact_search | Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes |
title_full | Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes Lena Josefine Daumann |
title_fullStr | Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes Lena Josefine Daumann |
title_full_unstemmed | Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes Lena Josefine Daumann |
title_short | Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes |
title_sort | spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes |
topic | Chemie Spectroscopy Biochemical engineering Enzymes Chemistry |
topic_facet | Chemie Spectroscopy Biochemical engineering Enzymes Chemistry Hochschulschrift |
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